General Information of the Compound
Compound ID
CP0496652
Compound Name
(S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentylamide 1-diphenylamide 2-({2-[(2-methoxy-benzyl)-methyl-amino]-ethyl}-amide)
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Structure
Formula
C40H56N6O4
Molecular Weight
684.926
Canonical SMILES
CCCCCN(CCCCC)C(=O)N1CCN([C@@H](C1)C(=O)NCCN(C)Cc1ccccc1OC)C(=O)N(c1ccccc1)c1ccccc1
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InChI
InChI=1S/C40H56N6O4/c1-5-7-17-26-43(27-18-8-6-2)39(48)44-29-30-45(40(49)46(34-20-11-9-12-21-34)35-22-13-10-14-23-35)36(32-44)38(47)41-25-28-42(3)31-33-19-15-16-24-37(33)50-4/h9-16,19-24,36H,5-8,17-18,25-32H2,1-4H3,(H,41,47)/t36-/m0/s1
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InChIKey
XCZYDSYUGXBLRG-BHVANESWSA-N
Physicochemical Property
logP
6.9901
Rotatable Bonds
17
Heavy Atom Count
50
Polar Areas
88.67
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
50

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44324775
ChEMBL ID
CHEMBL93401
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01410, Substance-P receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 9 nM
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