Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-benzyloxy-2-(3-methoxybenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
    Show/Hide
 PubChem ID
CID: 44297359
Canonical SMILES
COc1cccc(CNC(COCc2ccccc2)C(=O)N2CCC3(CN(c4ccccc34)S(C)(=O)=O)CC2)c1
    Show/Hide
Compound Formula C31H37N3O5S
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 71 nM
   TI
   LI
   LO
   TS