Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S,4R)-N-((2H-1,2,3-triazol-4-yl)methyl)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidine-1-carboxamide
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 PubChem ID
CID: 44444677
Canonical SMILES
C[C@@H](O[C@@H]1CN(C[C@H]1c1ccc(F)cc1)C(=O)NCc1cnn[nH]1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
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Compound Formula C24H22F7N5O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.58 nM
   TI
   LI
   LO
   TS