Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[1-[(4-acetamido-4-phenylpiperidin-1-yl)-[2-[4-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(3,4-dichlorophenyl)piperazin-1-yl]-2-oxoethyl]amino]-4-phenylpiperidin-4-yl]acetamide
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 PubChem ID
CID: 44337080
Canonical SMILES
CC(=O)NC1(CCN(CC1)N(CC(=O)N1CCN(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC1c1ccc(Cl)c(Cl)c1)N1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccccc1
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Compound Formula C47H51Cl2F6N7O3
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 148 nM
   TI
   LI
   LO
   TS