Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-trans-5-(((2-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)ethyl)(methyl)amino)methyl)-2H-1,2,4-triazol-3(4H)-one
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 PubChem ID
CID: 136043849
Canonical SMILES
CN(CC[C@@H]1CC[C@H](OCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@H]1c1ccccc1)Cc1n[nH]c(=O)[nH]1
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Compound Formula C26H28F6N4O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4.9 nM
   TI
   LI
   LO
   TS