Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-benzylamino-3-(3,4-dichlorobenzyloxy)-1-spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-yl-(2S)-propan-1-one
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 PubChem ID
CID: 21308490
Canonical SMILES
Clc1ccc(COC[C@H](NCc2ccccc2)C(=O)N2CCC3(CCc4ccccc34)CC2)cc1Cl
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Compound Formula C30H32Cl2N2O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 602 nM
   TI
   LI
   LO
   TS