Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[[3,5-bis(trifluoromethyl)phenyl]methyl]-8-(2-naphthalen-1-ylethylsulfonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
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 PubChem ID
CID: 44318486
Canonical SMILES
FC(F)(F)c1cc(CN2C(=O)NC3(CCN(CC3)S(=O)(=O)CCc3cccc4ccccc34)C2=O)cc(c1)C(F)(F)F
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Compound Formula C28H25F6N3O4S
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 74.13 nM
   TI
   LI
   LO
   TS