Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethylamino]-methyl}-2,4-dihydro-[1,2,4]triazol-3-one
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 PubChem ID
CID: 136180337
Canonical SMILES
FC(F)(F)c1cc(COC[C@@H](NCc2n[nH]c(=O)[nH]2)c2ccccc2)cc(c1)C(F)(F)F
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Compound Formula C20H18F6N4O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2.4 nM
   TI
   LI
   LO
   TS