| Compound ID |
Compound Name |
Compound Formula |
|
CP0540048
|
2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5-methylindol-1-yl]acetic acid
Show/Hide
|
C26H26N4O4
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0475952
|
(4S)-5-(4-butoxycarbonylpiperazin-1-yl)-4-[[6-[(3S)-3-methoxypyrrolidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C30H40N6O7
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0426660
|
2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5,6-dimethylindol-1-yl]acetic acid
Show/Hide
|
C27H28N4O4
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0100779
|
ethyl 5-cyano-2-methyl-6-[3-[(4-methylphenyl)methylsulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate
Show/Hide
|
C22H24N4O5S
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 19 nM
|
|
|
|
CP0054221
|
ethyl 5-cyano-2-methyl-6-[4-[(4-methylphenyl)methylsulfonylcarbamoyl]piperidin-1-yl]pyridine-3-carboxylate
Show/Hide
|
C24H28N4O5S
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 23 nM
|
|
|
|
CP0540047
|
3-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5-methylindol-1-yl]propanoic acid
Show/Hide
|
C27H28N4O4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0556592
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)piperidin-1-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C29H38ClN7O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0475927
|
(4S)-5-(4-butoxycarbonylpiperazin-1-yl)-4-[[6-[(1S,2R)-2-(methoxymethyl)cyclopropyl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C30H39N5O7
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0295715
|
ethyl 6-[3-[(4-chlorophenyl)methylsulfonylcarbamoyl]azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate
Show/Hide
|
C21H21ClN4O5S
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 23 nM
|
|
|
|
CP0116124
|
ethyl 6-[4-(benzylsulfonylcarbamoyl)piperidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate
Show/Hide
|
C23H26N4O5S
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 25 nM
|
|
|
|
CP0120516
|
ethyl 5-cyano-6-[4-[(2,4-difluorophenyl)methylsulfonylcarbamoyl]piperidin-1-yl]-2-methylpyridine-3-carboxylate
Show/Hide
|
C23H24F2N4O5S
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0424536
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(2-phenyl-6-thiophen-3-ylpyrimidine-4-carbonyl)amino]pentanoic acid
Show/Hide
|
C27H29N5O6S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0424283
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H35ClN6O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0426668
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-[4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C34H36ClN7O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0556591
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-[4-[2-(dimethylamino)-2-oxoethyl]piperazin-1-yl]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C33H38ClN7O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0072394
|
ethyl 5-cyano-6-[3-[(4-fluorophenyl)methylsulfonylcarbamoyl]azetidin-1-yl]-2-methylpyridine-3-carboxylate
Show/Hide
|
C21H21FN4O5S
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0540053
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C37H39FN6O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0042856
|
ethyl 5-cyano-6-[4-[(4-fluorophenyl)methylsulfonylcarbamoyl]piperidin-1-yl]-2-methylpyridine-3-carboxylate
Show/Hide
|
C23H25FN4O5S
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 38 nM
|
|
|
|
CP0540051
|
1-[2-[(3S,7R,8aS)-7-hydroxy-3-methyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide
Show/Hide
|
C34H40N6O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0555065
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-[4-(2-methoxyethyl)piperazin-1-yl]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C32H37ClN6O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0550793
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(3S)-3-methoxypyrrolidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C28H36N6O7
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0154221
|
ethyl 6-[3-(benzylsulfonylcarbamoyl)azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate
Show/Hide
|
C21H22N4O5S
|
2
|
| 1 |
IC50 = 17 nM
|
|
|
| 2 |
IC50 = 33 nM
|
|
|
|
CP0483743
|
4-[2-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoylamino]-4-methylphenoxy]butanoic acid
Show/Hide
|
C26H30N4O5
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0540055
|
N-[6-(4-butanoyl-5-methylpyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C28H31ClN8O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0400243
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2-fluoroethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H37FN6O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0568960
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2,2-difluoroethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H36F2N6O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0375260
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2-methoxyethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C33H40N6O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0490034
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(1-hydroxy-2-methylpropan-2-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C27H35N5O7
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0550792
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(3-hydroxypiperidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C28H36N6O7
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0375262
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methoxy-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H36N6O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0428173
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(1S,2S)-2-(hydroxymethyl)cyclopropyl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C27H33N5O7
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0553469
|
4-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5-methylindol-1-yl]butanoic acid
Show/Hide
|
C28H30N4O4
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0508101
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[6-[[(3R)-oxolan-3-yl]amino]-2-phenylpyrimidine-4-carbonyl]amino]pentanoic acid
Show/Hide
|
C27H34N6O7
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0509070
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-(2-oxo-2-piperazin-1-ylethyl)indole-3-carboxamide
Show/Hide
|
C30H34N6O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0398866
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(4-methylpyrazol-1-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C27H31N7O6
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0533178
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(3,4-dimethylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0555062
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C30H33ClN6O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0553473
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-(3,4,5-trimethylpiperazin-1-yl)ethyl]indole-3-carboxamide
Show/Hide
|
C33H40N6O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0568959
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(cyclopropylmethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C34H40N6O3
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0154222
|
ethyl 5-cyano-6-[4-[(4-methoxyphenyl)methylsulfonylcarbamoyl]piperidin-1-yl]-2-methylpyridine-3-carboxylate
Show/Hide
|
C24H28N4O6S
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 58 nM
|
|
|
|
CP0481999
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(4-methoxyphenyl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C30H33N5O7
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0509063
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(dimethylamino)-2-oxoethyl]-5,6-dimethylindole-3-carboxamide
Show/Hide
|
C29H33N5O3
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0556584
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide;hydrochloride
Show/Hide
|
C31H37ClN6O3
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0395740
|
ethyl 5-cyano-2-methyl-6-[3-[(3-methylphenyl)methylsulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate
Show/Hide
|
C22H24N4O5S
|
2
|
| 1 |
IC50 = 32 nM
|
|
|
| 2 |
IC50 = 65 nM
|
|
|
|
CP0568957
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C33H38N6O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0381449
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-6-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H35ClN6O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0480710
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(2-hydroxypropan-2-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C26H33N5O7
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0456328
|
(4S)-4-[(6-tert-butyl-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C27H35N5O6
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0433090
|
ethyl 6-[4-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]piperidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate
Show/Hide
|
C20H21ClN4O5S2
|
2
|
| 1 |
IC50 = 39 nM
|
|
|
| 2 |
IC50 = 80 nM
|
|
|
|
CP0555061
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5,6-dimethyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide;hydrochloride
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0448284
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(4-hydroxycyclohexyl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C29H37N5O7
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0509076
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)cyclohexyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C30H39ClN6O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0400242
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H38N6O4
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0448285
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(1R,2R)-2-(methoxymethyl)cyclopropyl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C28H35N5O7
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0410575
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(4-cyclopropylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C33H38N6O3
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0419622
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(3S)-3-hydroxypyrrolidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C27H34N6O7
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0524150
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(4-methylpiperazin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C28H37N7O6
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0375258
|
1-[2-(3-aminopiperidin-1-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide
Show/Hide
|
C31H36N6O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0509069
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(3-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H36N6O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0410574
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[methyl-(1-methylpyrrolidin-3-yl)amino]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0555060
|
4-[1-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-6-methylindol-3-yl]butanoic acid
Show/Hide
|
C28H30N4O4
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0375265
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)-2-cyanophenyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H32ClN7O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0424282
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-6-fluoro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C30H32ClFN6O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0555063
|
5-bromo-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-6-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H35BrN6O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0509074
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-5-(trifluoromethyl)indole-3-carboxamide
Show/Hide
|
C31H33F3N6O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0452827
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(3R)-3-hydroxypyrrolidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C27H34N6O7
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0481930
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(2-phenyl-6-propan-2-ylpyrimidine-4-carbonyl)amino]pentanoic acid
Show/Hide
|
C26H33N5O6
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0459748
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(2-phenyl-6-pyridin-4-ylpyrimidine-4-carbonyl)amino]pentanoic acid
Show/Hide
|
C28H30N6O6
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0459749
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(1-hydroxypropan-2-ylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C26H34N6O7
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0140475
|
ethyl 6-[3-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate
Show/Hide
|
C18H17ClN4O5S2
|
2
|
| 1 |
IC50 = 59 nM
|
|
|
| 2 |
IC50 = 99 nM
|
|
|
|
CP0456327
|
(4S)-4-[(6-cyclopropyl-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C26H31N5O6
|
1
|
| 1 |
IC50 = 59.5 nM
|
|
|
|
CP0893864
|
Sodium 1-Amino-4-(4-hydroxy-3-methylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
Show/Hide
|
C21H15N2NaO6S
|
1
|
| 1 |
IC50 = 60.4 nM
|
|
|
|
CP0509064
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-[[(3S)-pyrrolidin-3-yl]amino]ethyl]indole-3-carboxamide
Show/Hide
|
C30H34N6O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0556587
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(2-imidazol-1-ylethylamino)-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C31H33N7O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0383997
|
(S)Ethyl 4-{4-Carboxy-2-[(2-phenylpyrimidine-4-carbonyl)amino]butyryl}piperazine-1-carboxylate
Show/Hide
|
C29H31N5O6
|
2
|
| 1 |
IC50 = 64 nM
|
|
|
| 2 |
Ki = 356 nM
|
|
|
|
CP0483746
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[3-(methylamino)piperidin-1-yl]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0509072
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]indole-3-carboxamide
Show/Hide
|
C32H35F3N6O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0553472
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(4-ethylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0461893
|
ethyl 5-cyano-2-methyl-6-[3-[(2-methylphenyl)methylsulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate
Show/Hide
|
C22H24N4O5S
|
2
|
| 1 |
IC50 = 67 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
|
CP0533179
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C32H36N6O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0375256
|
1-[2-(4-aminopiperidin-1-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide
Show/Hide
|
C31H36N6O3
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0533175
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[(1-methylpiperidin-3-yl)amino]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0424542
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[2-phenyl-6-(1H-pyrazol-4-yl)pyrimidine-4-carbonyl]amino]pentanoic acid
Show/Hide
|
C26H29N7O6
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0375259
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[3-(dimethylamino)piperidin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C33H40N6O3
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0540056
|
5-(4-butanoyl-5-methylpyrazol-1-yl)-2-[[5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carbonyl]amino]benzoic acid
Show/Hide
|
C31H33ClN6O5
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0459750
|
(4S)-4-[[6-(3-aminopyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C27H35N7O6
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0410532
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-cyano-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H33N7O3
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0509067
|
1-[2-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide
Show/Hide
|
C33H38N6O3
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0555059
|
4-[2-[[4-(4-ethoxycarbonyl-3,5-dimethylpyrazol-1-yl)phenyl]carbamoylamino]phenoxy]butanoic acid
Show/Hide
|
C25H28N4O6
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0509068
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-(4-propan-2-ylpiperazin-1-yl)ethyl]indole-3-carboxamide
Show/Hide
|
C33H40N6O3
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0410514
|
2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-2,5-dimethylindol-1-yl]acetic acid
Show/Hide
|
C27H28N4O4
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0533176
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[methyl-[(1-methylpiperidin-3-yl)methyl]amino]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C34H42N6O3
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0540052
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[(1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C31H34N6O3
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0509066
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[3-(dimethylamino)pyrrolidin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0426661
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[1-(dimethylamino)propan-2-ylamino]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C31H38N6O3
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0510436
|
ethyl 5-cyano-6-[3-(cyclohexylmethylsulfonylcarbamoyl)azetidin-1-yl]-2-methylpyridine-3-carboxylate
Show/Hide
|
C21H28N4O5S
|
2
|
| 1 |
IC50 = 89 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
|
CP0556590
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C33H38N6O3
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0483745
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[2-(dimethylamino)ethylamino]-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C30H36N6O3
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0375254
|
methyl 2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5-methylindol-1-yl]acetate
Show/Hide
|
C27H28N4O4
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0483744
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[methyl-[2-(methylamino)ethyl]amino]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C30H36N6O3
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0509065
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[3-(methylamino)pyrrolidin-1-yl]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H36N6O3
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0556589
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(4-methyl-1,4-diazepan-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0396884
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[2-phenyl-6-(propan-2-ylamino)pyrimidine-4-carbonyl]amino]pentanoic acid
Show/Hide
|
C26H34N6O6
|
1
|
| 1 |
IC50 = 95.5 nM
|
|
|
|
CP0490035
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(1-methoxypropan-2-ylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C27H36N6O7
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0452823
|
(4S)-4-[(6-butyl-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C27H35N5O6
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0555064
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5,6-dichloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C30H32Cl2N6O3
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0424540
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[(6-morpholin-4-yl-2-phenylpyrimidine-4-carbonyl)amino]-5-oxopentanoic acid
Show/Hide
|
C27H34N6O7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0540050
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-[2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]indole-3-carboxamide
Show/Hide
|
C36H44N6O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0381445
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(3,5-dimethylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0533177
|
1-[2-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H36N6O3
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0375266
|
ethyl 5-cyano-2-methyl-6-[3-[[3-(trifluoromethyl)phenyl]methylsulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate
Show/Hide
|
C22H21F3N4O5S
|
2
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 290 nM
|
|
|
|
CP0553470
|
1-[2-[2-(aminomethyl)piperidin-1-yl]-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0375257
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[4-(methylamino)piperidin-1-yl]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0553471
|
1-[2-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[2,3-c]pyrrol-5-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide
Show/Hide
|
C32H36N6O3
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0568961
|
6-bromo-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H35BrN6O3
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0403953
|
ethyl 6-[4-(benzenesulfonylcarbamoyl)piperidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate
Show/Hide
|
C22H24N4O5S
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 710 nM
|
|
|
|
CP0568958
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(4-butylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide
Show/Hide
|
C34H42N6O3
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0456329
|
(4S)-4-[[6-(benzylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C30H34N6O6
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0556586
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[methyl(2-pyrrolidin-1-ylethyl)amino]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C33H40N6O3
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0452824
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(1-oxidopyridin-1-ium-3-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C28H30N6O7
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0510435
|
ethyl 5-chloro-6-[4-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]piperidin-1-yl]pyridine-3-carboxylate
Show/Hide
|
C18H19Cl2N3O5S2
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
|
CP0509075
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-6-chloro-5-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C31H35ClN6O3
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0556588
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[(1-methylpiperidin-4-yl)amino]-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0452826
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(ethylsulfonylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C25H32N6O8S
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0553474
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-fluoro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C30H33FN6O3
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0566986
|
N-[4-(4-acetyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
|
C28H29ClN6O3
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0072393
|
ethyl 5-cyano-2-methyl-6-[4-[(4-propan-2-ylphenyl)methylsulfonylcarbamoyl]piperidin-1-yl]pyridine-3-carboxylate
Show/Hide
|
C26H32N4O5S
|
2
|
| 1 |
IC50 = 160 nM
|
|
|
| 2 |
IC50 = 250 nM
|
|
|
|
CP0410390
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[2-phenyl-6-(propylamino)pyrimidine-4-carbonyl]amino]pentanoic acid
Show/Hide
|
C26H34N6O6
|
1
|
| 1 |
IC50 = 162 nM
|
|
|
|
CP0410391
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(2-hydroxyethylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C25H32N6O7
|
1
|
| 1 |
IC50 = 169 nM
|
|
|
|
CP0429090
|
(4S)-4-[(6-anilino-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C29H32N6O6
|
1
|
| 1 |
IC50 = 177 nM
|
|
|
|
CP0452825
|
(4S)-4-[(6-benzamido-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C30H32N6O7
|
1
|
| 1 |
IC50 = 178 nM
|
|
|
|
CP0375255
|
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-(2-pyrrolidin-1-ylethylamino)ethyl]indole-3-carboxamide
Show/Hide
|
C32H38N6O3
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0523037
|
(4S)-4-[[6-(2-carboxyethylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C26H32N6O8
|
1
|
| 1 |
IC50 = 198 nM
|
|
|
|
CP0432333
|
ethyl 6-[3-(benzenesulfonylcarbamoyl)azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate
Show/Hide
|
C20H20N4O5S
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 840 nM
|
|
|
|
CP0481928
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(2-phenyl-6-piperidin-1-ylpyrimidine-4-carbonyl)amino]pentanoic acid
Show/Hide
|
C28H36N6O6
|
1
|
| 1 |
IC50 = 201 nM
|
|
|
|
CP0537536
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(3-hydroxypropyl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C26H33N5O7
|
1
|
| 1 |
IC50 = 218 nM
|
|
|
|
CP0481850
|
(4S)-4-[[6-(cyclohexanecarbonylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
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C30H38N6O7
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1
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| 1 |
IC50 = 219 nM
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CP0465458
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ethyl 5-cyano-2-methyl-6-[3-(2-phenylethylsulfonylcarbamoyl)azetidin-1-yl]pyridine-3-carboxylate
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C22H24N4O5S
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1
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| 1 |
IC50 = 220 nM
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CP0396883
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CHEMBL3322636
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C29H38N6O7
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1
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| 1 |
IC50 = 223 nM
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CP0432332
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ethyl 5-cyano-6-[3-[[4-(hydroxymethyl)phenyl]methylsulfonylcarbamoyl]azetidin-1-yl]-2-methylpyridine-3-carboxylate
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C22H24N4O6S
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2
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| 1 |
IC50 = 230 nM
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| 2 |
IC50 = 730 nM
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CP0452822
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(2-morpholin-4-ylethylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
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C29H39N7O7
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1
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| 1 |
IC50 = 257 nM
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CP0428172
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(4S)-4-[[6-(benzenesulfonamido)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
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C29H32N6O8S
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1
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| 1 |
IC50 = 266 nM
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CP0568962
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N-[4-(4-butanoyl-5-methylpyrazol-1-yl)-2-carbamoylphenyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
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C31H34ClN7O4
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1
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| 1 |
IC50 = 266 nM
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CP0540049
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2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-4,5-dimethylindol-1-yl]acetic acid
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C27H28N4O4
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1
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| 1 |
IC50 = 272 nM
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CP0375264
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N-[5-(4-butanoyl-5-methylpyrazol-1-yl)pyrazin-2-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide
Show/Hide
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C28H31ClN8O3
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1
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| 1 |
IC50 = 275 nM
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CP0508198
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(3-hydroxypropylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
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C26H34N6O7
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1
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| 1 |
IC50 = 279 nM
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CP0475951
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(4S)-4-[[6-[2-[(dimethylamino)methyl]piperidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C31H43N7O6
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1
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| 1 |
IC50 = 291 nM
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CP0509062
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2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-methylcarbamoyl]-5-methylindol-1-yl]acetic acid
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C27H28N4O4
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1
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| 1 |
IC50 = 304 nM
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CP0432334
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ethyl 5-chloro-6-[3-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate
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C16H15Cl2N3O5S2
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2
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| 1 |
IC50 = 310 nM
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| 2 |
IC50 = 500 nM
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CP0540054
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5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-N-[4-(5-methyl-4-propanoylpyrazol-1-yl)phenyl]indole-3-carboxamide
Show/Hide
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C29H31ClN6O3
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1
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| 1 |
IC50 = 336 nM
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CP0424543
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(morpholin-4-ylmethyl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid
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C28H36N6O7
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1
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| 1 |
IC50 = 428 nM
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CP0553475
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[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl] 5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxylate
Show/Hide
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C30H32ClN5O4
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1
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| 1 |
IC50 = 480 nM
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CP0463439
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[2-phenyl-6-(piperidin-1-ylmethyl)pyrimidine-4-carbonyl]amino]pentanoic acid
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C29H38N6O6
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1
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| 1 |
IC50 = 533 nM
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CP0566987
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1-[1-[4-[5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carbonyl]-2,3-dihydro-1,4-benzoxazin-7-yl]-5-methylpyrazol-4-yl]butan-1-one
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C32H35ClN6O4
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1
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| 1 |
IC50 = 559 nM
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CP0375263
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5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-N-[4-[5-methyl-4-(4,4,4-trifluorobutanoyl)pyrazol-1-yl]phenyl]indole-3-carboxamide
Show/Hide
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C30H30ClF3N6O3
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1
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| 1 |
IC50 = 574 nM
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CP0509061
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ethyl 1-[4-[(4-chlorophenyl)carbamoylamino]phenyl]-3,5-dimethylpyrazole-4-carboxylate
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C21H21ClN4O3
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1
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| 1 |
IC50 = 1260 nM
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CP0509060
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ethyl 1-[4-[(2-methoxyphenyl)methylcarbamoyl]phenyl]-3,5-dimethylpyrazole-4-carboxylate
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C23H25N3O4
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1
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| 1 |
IC50 = 1540 nM
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CP0885816
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Sodium 1-Amino-4-[4-(3,4-dimethylphenylthio)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C28H21N2NaO5S2
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1
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| 1 |
IC50 = 2340 nM
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CP0894768
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Sodium 1-Amino-4-[4-(2,4-dimethylphenylthio)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C28H21N2NaO5S2
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1
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| 1 |
IC50 = 2410 nM
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CP0523057
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(4S)-4-[[6-[2-(dimethylamino)ethylamino]-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
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C27H37N7O6
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1
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| 1 |
IC50 = 2780 nM
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CP0854864
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Sodium 1-Amino-4-[4-(2,5-dimethylphenylthio)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C28H21N2NaO5S2
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1
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| 1 |
IC50 = 2960 nM
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CP0652102
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sodium 1-amino-9,10-dioxo-4-(phenylamino)-9,10-dihydroanthracene-2-sulfonate
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C20H13N2NaO5S
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1
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| 1 |
IC50 = 3120 nM
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CP0893862
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Sodium 1-Amino-4-[4-(3-pyridin-3-ylmethylthio)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C26H18N3NaO5S2
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1
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| 1 |
IC50 = 3590 nM
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CP0032210
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4-(4-piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
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C29H24F3NO2
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1
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| 1 |
IC50 > 10000 nM
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CP0851936
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sodium 1-amino-9,10-dioxo-4-(4-(phenylamino)-3-sulfonatophenylamino)-9,10-dihydroanthracene-2-sulfonate
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C26H17N3Na2O8S2
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1
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| 1 |
Kd = 0.1585 nM
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CP0087103
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-(ethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C34H46N6O7
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2
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| 1 |
Ki = 0.38 nM
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| 2 |
Ki = 0.68 nM
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CP0189076
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(4-(pyrrolidin-1-ylmethyl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
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C36H51N7O6
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1
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| 1 |
Ki = 0.4 nM
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CP0189074
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
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C36H49N7O7
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1
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| 1 |
Ki = 0.46 nM
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CP0498717
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(S)-4-(4-(4-(ethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H48N6O7
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1
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| 1 |
Ki = 0.58 nM
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CP0254408
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(S)-4-(6-(4-(ethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H47N7O7
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1
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| 1 |
Ki = 0.6 nM
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CP0506501
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(4S)-4-[(6-{4-[(diethylamino)methyl]piperidin-1-yl}-2-phenylpyrimidin-4-yl)formamido]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
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C36H53N7O6
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1
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| 1 |
Ki = 0.61 nM
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CP0532602
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(S)-4-(4-(3-carbamoylazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
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C31H40N6O7
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1
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| 1 |
Ki = 0.64 nM
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CP0535227
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(S)-4-(6-(4-(2-(ethylamino)-2-oxoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H49N7O7
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1
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| 1 |
Ki = 0.67 nM
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CP0506503
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(S)-4-(6-(4-aminopiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H43N7O6
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1
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| 1 |
Ki = 0.69 nM
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CP0494757
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
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C35H47N7O7
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1
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| 1 |
Ki = 0.7 nM
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CP0089673
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(S)-4-(6-(4-(2-hydroxyethoxy)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H46N6O8
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1
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| 1 |
Ki = 0.71 nM
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CP0439242
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-(diethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
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C35H49N7O7
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1
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| 1 |
Ki = 0.79 nM
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CP0372050
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(4-(4-((2-oxopyrrolidin-1-yl)methyl)piperidin-1-yl)-6-phenylpicolinamido)pentanoic acid
Show/Hide
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C36H48N6O7
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1
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| 1 |
Ki = 0.79 nM
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CP0525484
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(4S)-5-(4-butoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
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C35H47N7O9
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1
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| 1 |
Ki = 0.8 nM
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CP0439241
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(S)-4-(6-(4-(azetidine-1-carbonyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H47N7O7
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1
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| 1 |
Ki = 0.83 nM
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CP0541510
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(S)-4-(6-(4-(2-(methylamino)-2-oxoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H47N7O7
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1
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| 1 |
Ki = 0.9 nM
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CP0418164
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(S)-4-(6-(4-(2-(azetidin-1-yl)-2-oxoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C36H49N7O7
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1
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| 1 |
Ki = 0.92 nM
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CP0498715
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(S)-4-(4-(4-(dimethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H48N6O7
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1
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| 1 |
Ki = 0.98 nM
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CP0491253
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(S)-5-oxo-4-(6-(4-((2-oxopyrrolidin-1-yl)methyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C36H49N7O7
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1
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| 1 |
Ki = 0.99 nM
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CP0529859
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(S)-4-(6-morpholino-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C30H40N6O7
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1
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| 1 |
Ki = 1 nM
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CP0429734
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(4S)-4-[({4-[3-(Dimethylamino)propyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C32H45N5O6
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1
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| 1 |
Ki = 1 nM
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CP0415390
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(4S)-5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[4-(pyrrolidin-1-ylmethyl)piperidin-1-yl]pyridin-2-yl}-carbonyl)amino]pentanoic Acid
Show/Hide
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C37H52N6O6
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1
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| 1 |
Ki = 1.1 nM
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CP0463982
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C36H50N6O7
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1
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| 1 |
Ki = 1.1 nM
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CP0189073
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(S)-4-(6-(4-((methylamino)methyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H47N7O6
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1
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| 1 |
Ki = 1.2 nM
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CP0473784
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(S)-4-(6-(2-methoxyethoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C29H39N5O8
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1
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| 1 |
Ki = 1.2 nM
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CP0488877
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(S)-4-(6-(2-methoxyethylamino)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C29H40N6O7
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1
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| 1 |
Ki = 1.2 nM
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CP0494778
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(S)-4-(6-(3-ethoxyazetidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H42N6O7
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1
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| 1 |
Ki = 1.2 nM
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CP0506505
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(S)-4-(4-(2-methoxyethoxy)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C29H39N5O8
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1
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| 1 |
Ki = 1.2 nM
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CP0535231
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(S)-4-(6-(4-carbamoylpiperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H42N8O7
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1
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| 1 |
Ki = 1.2 nM
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CP0502340
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(S)-4-(4-(4-(azetidine-1-carbonyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C36H48N6O7
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1
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| 1 |
Ki = 1.2 nM
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CP0501378
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-morpholinopiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
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C34H47N7O7
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1
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| 1 |
Ki = 1.3 nM
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CP0535228
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-(dimethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
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C33H45N7O7
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1
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| 1 |
Ki = 1.3 nM
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CP0375636
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(4S)4-[({4-[(1-Acetylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C35H47N5O8
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1
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| 1 |
Ki = 1.3 nM
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CP0381216
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(4S)4-{[(4-{[1-(Ethoxycarbonyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C36H49N5O9
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1
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| 1 |
Ki = 1.3 nM
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CP0500067
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-methoxypiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
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C31H42N6O7
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1
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| 1 |
Ki = 1.4 nM
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CP0513905
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-((R)-3-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl)picolinamido)pentanoic acid
Show/Hide
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C36H48N6O7
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1
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| 1 |
Ki = 1.4 nM
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CP0375518
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(4S)4-{[(4-{[(2-Methoxyethoxy)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C35H49N5O9
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1
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| 1 |
Ki = 1.4 nM
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CP0513934
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-({[(piperidin-4-ylmethyl)amino]carbonyl}amino)pyridin-2-yl]carbonyl}amino)pentanoic acid
Show/Hide
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C38H55N7O7
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1
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| 1 |
Ki = 1.4 nM
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CP0089676
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(S)-4-(6-(4-(diethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C36H51N7O7
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1
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| 1 |
Ki = 1.5 nM
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CP0089677
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(4-(pyrrolidin-1-yl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
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C35H49N7O6
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0375650
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-[({6-phenyl-4-[4-(pyrrolidin-1-ylmethyl)piperidin-1-yl]pyridin-2-yl}carbonyl)amino]pentanoic Acid
Show/Hide
|
C36H50N6O6
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0502663
|
(4S)4-{[(4-{4-[(Methylamino)ethyl]piperidin-1-yl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
|
C34H48N6O6
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0518988
|
(S)-4-(4-(4-((ethylamino)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C35H50N6O6
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0471476
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-({[4-({[(3R)3-methoxypyrrolidin-1-yl]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-oxopentanoic Acid
Show/Hide
|
C32H41N5O9
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0523991
|
(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-({[methyl-(tetrahydro-2H-pyran-4-ylmethyl)mino]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid
Show/Hide
|
C34H45N5O9
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0507227
|
butyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-(2H-tetrazol-5-yl)butanoyl]piperazine-1-carboxylate
Show/Hide
|
C35H47N11O7
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0494691
|
(S)-5-oxo-4-(6-(4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C37H51N7O7
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0384515
|
(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-(4-(pyrrolidin-1-yl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
|
C34H47N7O6
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0421986
|
(S)-4-(4-(3-(methylcarbamoyl)azetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C32H42N6O7
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0498701
|
(S)-4-(4-((S)-3-(diethylcarbamoyl)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C36H50N6O7
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0510849
|
(S)-4-(4-(4-(2-amino-2-oxoethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H45N7O7
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0542752
|
(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-((S)-3-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl)picolinamido)pentanoic acid
Show/Hide
|
C36H48N6O7
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0453572
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(morpholin-4-ylcarbonyl)xy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
|
C31H39N5O9
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0502647
|
(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-{[(piperidin-4-ylmethoxy)carbonyl]amino}pyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
|
C38H54N6O8
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0523992
|
(4S)-4-[({4-[(4-Acetylpiperazin-1-yl)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C34H44N6O8
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0384277
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-({[4-({[methyl-(tetrahydrofuran-3-yl)mino]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid
Show/Hide
|
C32H41N5O9
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0498719
|
(4S)4-{[(4-{4-[(Dimethylamino)ethyl]piperidin-1-yl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
|
C35H50N6O6
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0518835
|
(4S)4-{[(4-{[(3-Aminopropoxy)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
|
C35H50N6O8
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0303192
|
(S)-4-(6-(4-carbamoylpiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C32H43N7O7
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0491246
|
(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(piperazin-1-yl)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
|
C30H41N7O6
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0534318
|
(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-(2-methoxyethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
|
C33H46N6O7
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0401970
|
(S)-4-(4-(3-methoxyazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C31H41N5O7
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0533226
|
(S)-4-(4-(3-(ethylcarbamoyl)azetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H44N6O7
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0429735
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[(dimethylamino)carbonyl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
|
C29H37N5O8
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0491244
|
(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
|
C37H53N7O6
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0494774
|
(S)-5-oxo-4-(6-(4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)piperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C36H50N8O7
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0069760
|
(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)picolinamido)pentanoic acid
Show/Hide
|
C36H48N6O7
|
2
|
| 1 |
Ki = 2.1 nM
|
|
|
| 2 |
Ki = 6.3 nM
|
|
|
|
CP0507679
|
(4S)-4-[({4-[3-(Dimethylamino)-3-oxopropyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C32H43N5O7
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0521448
|
(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-{[(4-ethoxypiperidin-1-yl)carbonyl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
|
C34H45N5O9
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0522018
|
(4S)4-[({4-[(2-Methoxyethyl)methyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C31H43N5O7
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0439159
|
(S)-4-(6-(4-((ethylamino)methyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C34H49N7O6
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0488878
|
(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(piperidin-4-ylmethoxy)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
|
C32H44N6O7
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0529853
|
(S)-4-(6-(4-(2-methoxyethyl)piperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H47N7O7
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0513915
|
(4S)4-({[4-({[Methyl(tetrahydrofuran-3-yl)mino]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C33H43N5O9
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0541361
|
(4S)4-{[(4-{[(4-Methylpiperazin-1-yl)acetyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
|
C37H53N7O7
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0371894
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(2-methoxyethyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoicAcid
Show/Hide
|
C29H39N5O7
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0500667
|
(4S)4-[({4-[4-(Hydroxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C33H45N5O7
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0522055
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(methoxyacetyl)iperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
|
C33H45N5O8
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0526328
|
(4S)-4-[({4-[(Dimethylamino)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C30H39N5O7
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0441470
|
(S)-4-(6-(3-hydroxyazetidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C29H38N6O7
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0531198
|
(S)-4-(6-(4-(dimethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C34H47N7O7
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0372041
|
(S)-4-(4-(3-hydroxyazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C30H39N5O7
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0497096
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(1-methylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
|
C33H45N5O7
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0502329
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(2-piperidin-3-ylethoxy)pyridin-2-yl]carbonyl}amino)pentanoicAcid
Show/Hide
|
C33H45N5O7
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0526329
|
(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-[({4-[(1-methylpiperidin-4-yl)xy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxopentanoicAcid
Show/Hide
|
C32H43N5O7
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0529854
|
(S)-4-(6-(4-(2-(dimethylamino)-2-oxoethyl)piperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C34H48N8O7
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0518877
|
(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-(dimethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
|
C34H46N6O7
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0532608
|
(S)-4-(4-((R)-3-(diethylcarbamoyl)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C36H50N6O7
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0429191
|
(4S)-4-{[(4-{[Ethyl(methyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C31H41N5O7
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0497097
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(methoxyacetyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid
Show/Hide
|
C35H47N5O9
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0513916
|
(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
|
C37H52N6O6
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0513917
|
(4S)-4-{[(4-{[(3-Methoxypropyl)(methyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)-carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C33H45N5O8
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0529850
|
(S)-4-(6-(4-(2-aminoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H47N7O6
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0529857
|
(S)-4-(6-(4-methylpiperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C31H43N7O6
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0510610
|
(4S)4-{[(4-{[(Isopropylamino)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
|
C35H50N6O7
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0522056
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(methylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
|
C32H44N6O6
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0494772
|
(S)-4-(6-(4-(2-(dimethylamino)ethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C35H51N7O6
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0503004
|
(S)-4-(6-(3-morpholinopropoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H46N6O8
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0135766
|
(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)picolinamido)pentanoic acid
Show/Hide
|
C37H50N6O7
|
2
|
| 1 |
Ki = 2.8 nM
|
|
|
| 2 |
Ki = 6.7 nM
|
|
|
|
CP0447795
|
(S)-4-(4-(4-(2-aminoethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C34H48N6O6
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0532623
|
(S)-4-(4-(4-(2-(dimethylamino)acetyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C35H49N7O7
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0371899
|
(4S)-5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(piperidin-1-ylcarbonyl)pyridin-2-yl]carbonyl}amino)-pentanoic Acid
Show/Hide
|
C33H43N5O7
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0507680
|
(4S)4-[({4-[(1-Acetylpiperidin-4-yl)oxy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-[4-(butoxycarbonyl)piperazin-1-yl]-5-oxopentanoicAcid
Show/Hide
|
C33H43N5O9
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0520430
|
(4S)-4-({[4-(5-Hydroxypentyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C32H44N4O7
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0529851
|
(S)-4-(6-(4-morpholinopiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C35H49N7O7
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0537576
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(S)-4-(6-(4-(dimethylcarbamoyl)piperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H46N8O7
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1
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| 1 |
Ki = 2.9 nM
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CP0374054
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3-(3-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
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C29H30N6O4S
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2
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| 1 |
Ki = 3 nM
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| 2 |
Ki = 10 nM
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CP0064676
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(S)-4-(6-(4-(aminomethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H45N7O6
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1
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| 1 |
Ki = 3 nM
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CP0374044
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(S)-4-(4-(4-(2-aminoethyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H47N7O6
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1
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| 1 |
Ki = 3 nM
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CP0510611
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(4S)4-[({4-[(Morpholin-4-ylacetyl)mino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C36H50N6O8
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1
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| 1 |
Ki = 3 nM
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CP0520432
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(2-piperidin-4-ylethoxy)pyridin-2-yl]carbonyl}amino)pentanoicAcid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 3 nM
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CP0506520
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(S)-4-(6-(4-(2-(diethylamino)-2-oxoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C37H53N7O7
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1
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| 1 |
Ki = 3.1 nM
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CP0452748
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(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxo-5-(4-propoxycarbonylpiperazin-1-yl)pentanoic acid
Show/Hide
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C34H45N7O9
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1
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| 1 |
Ki = 3.1 nM
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CP0463983
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{4-[(dimethylamino)ethyl]piperidin-1-yl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
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C34H48N6O6
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1
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| 1 |
Ki = 3.2 nM
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CP0383762
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(4S)4-{[(4-{[(4-Methylpiperazin-1-yl)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C33H45N7O7
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1
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| 1 |
Ki = 3.2 nM
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CP0502656
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(4S)-4-[({4-[(4-Methoxypiperidin-1-yl)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H45N5O8
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1
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| 1 |
Ki = 3.2 nM
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CP0507731
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(S)-4-(4-(3-morpholinoazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H46N6O7
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1
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| 1 |
Ki = 3.3 nM
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CP0373580
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-morpholin-4-yl-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
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C30H39N5O7
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1
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| 1 |
Ki = 3.3 nM
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CP0470900
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(4S)4-({[4-(4-Aminopiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoic Acid
Show/Hide
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C33H46N6O6
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1
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| 1 |
Ki = 3.3 nM
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CP0470901
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(4S)-4-[({4-[4-(Dimethylamino)butyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C33H47N5O6
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1
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| 1 |
Ki = 3.3 nM
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CP0418165
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(S)-4-(4-(4-carbamoylpiperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H43N7O7
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1
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| 1 |
Ki = 3.5 nM
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CP0452735
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(S)-4-(4-((R)-3-(2-(diethylamino)-2-oxoethoxy)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C37H52N6O8
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1
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| 1 |
Ki = 3.5 nM
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CP0383877
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(piperidin-4-yloxy)yridin-2-yl]carbonyl}amino)entanoicAcid
Show/Hide
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C32H43N5O7
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2
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| 1 |
Ki = 3.5 nM
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| 2 |
Ki = 3.8 nM
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CP0383878
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(4S)4-({[4-(4-Aminopiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-[4-(butoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
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C31H42N6O6
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1
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| 1 |
Ki = 3.5 nM
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CP0494756
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(4-phenyl-6-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)pyrimidine-2-carboxamido)pentanoic acid
Show/Hide
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C36H49N7O7
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1
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| 1 |
Ki = 3.6 nM
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CP0531197
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(S)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C36H51N7O7
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1
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| 1 |
Ki = 3.6 nM
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CP0371901
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(4S)4-[({4-[(1-Acetylpiperidin-4-ylo)xy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid
Show/Hide
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C34H45N5O9
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1
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| 1 |
Ki = 3.6 nM
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CP0383880
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(4S)-4-({[4-(4-Hydroxybutyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C31H42N4O7
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1
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| 1 |
Ki = 3.6 nM
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CP0494776
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(S)-4-(6-(4-acetylpiperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H43N7O7
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1
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| 1 |
Ki = 3.7 nM
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CP0371902
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(pyrrolidin-3-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid
Show/Hide
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C30H39N5O7
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1
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| 1 |
Ki = 3.7 nM
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CP0507662
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(2-piperidin-2-ylethoxy)pyridin-2-yl]carbonyl}amino)pentanoicAcid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 3.7 nM
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CP0522061
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(4S)-4-({[4-(3-Morpholin-4-yl-3-oxopropyl)-6-phenylpyridin-2-yl]carbonyl}amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H45N5O8
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1
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| 1 |
Ki = 3.7 nM
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CP0528652
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-3-ylmethoxy)yridin-2-yl]carbonyl}amino)pentanoicAcid
Show/Hide
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C32H43N5O7
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1
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| 1 |
Ki = 3.7 nM
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CP0463985
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-((ethylamino)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C34H48N6O6
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1
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| 1 |
Ki = 3.8 nM
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CP0520520
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(4S)-4-({[4-(3-Hydroxypropyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C30H40N4O7
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1
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| 1 |
Ki = 3.8 nM
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CP0526330
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(4S)4-[({4-[(1-Acetylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-[4-(butoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
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C34H45N5O8
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1
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| 1 |
Ki = 3.9 nM
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CP0463926
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(2R,5S)-1-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)pyrrolidine-2,5-dicarboxamide
Show/Hide
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C31H33N7O3S
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2
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| 1 |
Ki = 4 nM
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| 2 |
Ki = 21 nM
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CP0383882
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{4-[(methylamino)ethyl]piperidin-1-yl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
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C33H46N6O6
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1
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| 1 |
Ki = 4 nM
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CP0502341
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(S)-4-(4-(4-((diethylamino)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C37H54N6O6
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1
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| 1 |
Ki = 4 nM
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CP0513913
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(S)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C37H52N6O7
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1
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| 1 |
Ki = 4 nM
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CP0383881
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(2-methoxyethyl)methyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C30H41N5O7
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1
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| 1 |
Ki = 4 nM
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CP0491248
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(4S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(pyrrolidin-3-ylmethylamino)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
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C31H43N7O6
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1
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| 1 |
Ki = 4.1 nM
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CP0383763
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(4S)4-[({4-[(N,N-Dimethylglycyl)mino]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C35H50N6O7
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1
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| 1 |
Ki = 4.1 nM
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CP0473782
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(4-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)pyrimidine-2-carboxamido)pentanoic acid
Show/Hide
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C37H53N7O6
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1
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| 1 |
Ki = 4.2 nM
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CP0506319
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-4-ylmethoxy)pyridin-2-yl]carbonyl}amino)pentanoicAcid
Show/Hide
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C32H43N5O7
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1
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| 1 |
Ki = 4.2 nM
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CP0534319
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(S)-4-(6-(4-((2-methoxyethoxy)methyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H50N6O8
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1
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| 1 |
Ki = 4.3 nM
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CP0383855
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-(isopropylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C35H48N6O7
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1
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| 1 |
Ki = 4.3 nM
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CP0513918
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(4S)-4-({[4-(Morpholin-4-ylcarbonyl)-6-phenylpyridin-2-yl]carbonyl}amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C32H41N5O8
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1
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| 1 |
Ki = 4.4 nM
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CP0439240
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(S)-4-(6-(2-hydroxyethylthio)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C28H37N5O7S
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1
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| 1 |
Ki = 4.5 nM
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CP0372048
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(S)-4-(4-(4-(2-aminoethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H47N7O6
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1
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| 1 |
Ki = 4.5 nM
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CP0384054
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(1-isopropylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C35H49N5O7
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1
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| 1 |
Ki = 4.5 nM
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CP0470903
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(piperidin-4-ylmethoxy)pyridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 4.5 nM
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CP0519138
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]methoxy}pyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C35H44F3N5O8
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1
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| 1 |
Ki = 4.5 nM
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CP0520405
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(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-({[6-phenyl-4-(piperidin-4-ylmethoxy)pyridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
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C34H47N5O7
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1
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| 1 |
Ki = 4.5 nM
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CP0502241
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(4S)-5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(tetrahydro-2H-pyran-4-ylamino)carbonyl]pyridin-2-yl}carbonyl)amino]pentanoic Acid
Show/Hide
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C33H43N5O8
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1
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| 1 |
Ki = 4.6 nM
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CP0502653
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(4S)4-[({4-[({[2-(Dimethylamino)2-oxoethyl]amino}carbonyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C36H51N7O8
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1
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| 1 |
Ki = 4.7 nM
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CP0529858
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(S)-4-(6-(3-(dimethylamino)propylamino)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H45N7O6
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1
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| 1 |
Ki = 4.8 nM
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CP0372049
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(S)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-(4-(hexyloxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C38H54N6O7
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1
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| 1 |
Ki = 4.8 nM
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CP0470079
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(4S)4-[({4-[(Morpholin-4-ylcarbonyl)oxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C32H41N5O9
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1
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| 1 |
Ki = 4.8 nM
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CP0373538
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(S)-4-(4-(4-(2-(dimethylamino)-2-oxoethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H49N7O7
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1
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| 1 |
Ki = 4.9 nM
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CP0371903
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(4S)4-({[4-({[(3S)3-Methoxypyrrolidin-1-yl]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C33H43N5O9
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1
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| 1 |
Ki = 4.9 nM
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CP0513919
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(4-hydroxybutoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
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C30H40N4O8
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1
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| 1 |
Ki = 4.9 nM
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CP0383619
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(2S,4S)-1-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)-4-hydroxypyrrolidine-2-carboxylic acid
Show/Hide
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C30H31N5O4S
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2
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| 1 |
Ki = 5 nM
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| 2 |
Ki = 31 nM
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CP0436664
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(S)-4-(6-(4-methoxypiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H44N6O7
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1
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| 1 |
Ki = 5 nM
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CP0532615
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(S)-4-(4-((S)-3-(2-(dimethylamino)-2-oxoethoxy)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H48N6O8
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1
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| 1 |
Ki = 5 nM
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CP0371904
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(4S)4-[({4-[(1-Methylpiperidin-4-yl)xy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 5 nM
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CP0507664
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(dimethylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C33H46N6O6
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1
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| 1 |
Ki = 5 nM
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CP0495649
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ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-(2H-tetrazol-5-yl)butanoyl]piperazine-1-carboxylate
Show/Hide
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C33H43N11O7
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1
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| 1 |
Ki = 5 nM
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CP0495650
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(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-cyclobutyloxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C35H45N7O9
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1
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| 1 |
Ki = 5 nM
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CP0513920
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(4S)4-{[(4-{[1-(Ethylsulfonyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H47N5O9S
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1
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| 1 |
Ki = 5.1 nM
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CP0503003
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(S)-4-(4-(2-methoxyethylamino)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C29H40N6O7
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1
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| 1 |
Ki = 5.2 nM
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CP0507732
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(S)-5-oxo-4-(4-(4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C37H51N7O7
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1
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| 1 |
Ki = 5.2 nM
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CP0496642
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(S)-4-(6-(4-(2-methoxyethoxy)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H48N6O8
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1
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| 1 |
Ki = 5.3 nM
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CP0427010
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-{[1-(ethylsulfonyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid
Show/Hide
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C34H47N5O9S
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1
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| 1 |
Ki = 5.3 nM
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CP0470904
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(4S)4-[({4-[(1-Methylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H47N5O7
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1
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| 1 |
Ki = 5.3 nM
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CP0507665
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(4S)4-{[(4-{[1-(2-Methoxyethyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C36H51N5O8
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1
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| 1 |
Ki = 5.3 nM
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CP0520406
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-{[1-(2-methoxyethyl)iperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid
Show/Hide
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C35H49N5O8
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1
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| 1 |
Ki = 5.3 nM
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CP0384056
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(4S)-4-{[(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
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C35H48N6O7
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1
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| 1 |
Ki = 5.4 nM
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CP0372044
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(4S)-4-(4-(3-aminopiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H44N6O6
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1
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| 1 |
Ki = 5.5 nM
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CP0542751
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(S)-4-(4-(3-(dimethylamino)azetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H44N6O6
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1
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| 1 |
Ki = 5.5 nM
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CP0421852
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(4S)4-[({4-[(1-Isopropylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
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C36H51N5O7
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1
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| 1 |
Ki = 5.5 nM
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CP0499275
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-piperidin-1-ylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C32H43N5O6
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1
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| 1 |
Ki = 5.5 nM
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CP0507666
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(4S)4-{[(4-{[(Dimethylamino)carbonyl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C30H39N5O8
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1
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| 1 |
Ki = 5.5 nM
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CP0439749
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(4S)4-{[(4,6-Diphenylpyridin-2-yl)carbonyl]amino}-5-[4-(3-methylphenyl)iperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
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C34H34N4O4
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2
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| 1 |
Ki = 5.7 nM
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| 2 |
Ki = 150 nM
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CP0439160
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(S)-4-(6-((1-methylpiperidin-4-yl)methoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H46N6O7
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1
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| 1 |
Ki = 5.7 nM
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CP0407486
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(4S)4-[({4-[(N-Methylglycyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C34H48N6O7
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1
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| 1 |
Ki = 5.7 nM
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CP0507667
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(4S)4-[({4-[(2-Hydroxyethyl)amino]-6-phenylpyridin-2-yl}-carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid
Show/Hide
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C29H39N5O7
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1
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| 1 |
Ki = 5.7 nM
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CP0482443
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(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxo-5-(4-phenylmethoxycarbonylpiperazin-1-yl)pentanoic acid
Show/Hide
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C38H45N7O9
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1
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| 1 |
Ki = 5.7 nM
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CP0494775
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(S)-4-(4-(4-carbamoylpiperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H42N8O7
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1
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| 1 |
Ki = 5.8 nM
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CP0513921
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(4S)-4-{[(4-{[Butyl(methyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 5.8 nM
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CP0520407
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(4S)-4-[({4-[(4-Methylpiperazin-1-yl)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C33H44N6O7
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1
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| 1 |
Ki = 5.8 nM
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CP0528054
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(piperidin-1-ylcarbonyl)mino]pyridin-2-yl}carbonyl)amino]pentanoic acid
Show/Hide
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C37H52N6O7
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1
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| 1 |
Ki = 5.8 nM
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CP0514380
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(S)-4-(4-(4-morpholinopiperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H49N7O7
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1
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| 1 |
Ki = 5.9 nM
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CP0372047
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(S)-4-(4-(4-(2-(diethylamino)-2-oxoethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C37H53N7O7
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1
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| 1 |
Ki = 5.9 nM
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CP0523999
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(S)-4-(4-(4-(dimethylcarbamoyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H47N7O7
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1
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| 1 |
Ki = 5.9 nM
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CP0452727
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(4S)-5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-({[4-(3-methoxypropoxy)-6-phenylpyridin-2-yl]carbonyl}amino)-5-oxopentanoicAcid
Show/Hide
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C30H40N4O8
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1
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| 1 |
Ki = 5.9 nM
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CP0498716
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(S)-4-(4-(4-(isopropylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C36H50N6O7
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1
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| 1 |
Ki = 6 nM
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CP0473491
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(4S)5-Oxo-5-{4-[(pentylamino)carbonothioyl]piperazin-1-yl}-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C31H43N5O4S
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1
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| 1 |
Ki = 6 nM
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CP0489162
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(4S)4-{[(4-{[(4-Ethoxypiperidin-1-yl)carbonyl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
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C35H47N5O9
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1
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| 1 |
Ki = 6 nM
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CP0384058
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(4S)-4-{[(4-{[(3-Methoxypropyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C32H43N5O8
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1
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| 1 |
Ki = 6.1 nM
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CP0510710
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(4S)4-({[4-(Acetylamino)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 6.2 nM
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CP0498704
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(S)-4-(4-(4-carbamoylpiperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H43N7O7
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1
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| 1 |
Ki = 6.3 nM
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CP0513912
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-(2-propoxyethyl)piperazin-1-yl)picolinamido)pentanoic acid
Show/Hide
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C36H52N6O7
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1
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| 1 |
Ki = 6.3 nM
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CP0507735
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(S)-4-(4-(4-carbamoylpiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H44N6O7
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1
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| 1 |
Ki = 6.5 nM
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CP0542755
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(piperazin-1-yl)picolinamido)pentanoic acid
Show/Hide
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C31H42N6O6
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1
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| 1 |
Ki = 6.5 nM
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CP0384059
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(4S)4-[({4-[4-(Methylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C33H46N6O6
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1
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| 1 |
Ki = 6.5 nM
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CP0520408
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(4S)4-{[(4-{[1-(Ethoxycarbonyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoicAcid
Show/Hide
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C35H47N5O9
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1
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| 1 |
Ki = 6.5 nM
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CP0476883
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butyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-hydroxypentanoyl]piperazine-1-carboxylate
Show/Hide
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C35H49N7O8
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1
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| 1 |
Ki = 6.5 nM
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CP0491245
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(S)-4-(4-(4-(2-(dimethylamino)-2-oxoethyl)piperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H48N8O7
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1
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| 1 |
Ki = 6.8 nM
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CP0492722
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(3-hydroxypropoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
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C29H38N4O8
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1
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| 1 |
Ki = 6.9 nM
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CP0507668
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-3-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid
Show/Hide
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C31H41N5O7
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1
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| 1 |
Ki = 6.9 nM
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CP0372053
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(4S)4-[({4-[4-(Aminomethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C33H46N6O6
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2
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| 1 |
Ki = 7 nM
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| 2 |
Ki = 15 nM
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CP0496189
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(4S)5-{4-[(Heptyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C29H38N4O6
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1
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| 1 |
Ki = 7 nM
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CP0513922
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(4S)4-[({4-[(1-Isopropylpiperidin-4-yl)oxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C35H49N5O7
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1
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| 1 |
Ki = 7 nM
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CP0541511
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(S)-4-(4-(4-(2-methoxyethoxy)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H48N6O8
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1
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| 1 |
Ki = 7.1 nM
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CP0463997
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(S)-4-(4-(3-((methylamino)methyl)azetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H44N6O6
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1
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| 1 |
Ki = 7.1 nM
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CP0523998
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(4S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(3-(pyrrolidin-1-ylmethyl)piperidin-1-yl)picolinamido)pentanoic acid
Show/Hide
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C37H52N6O6
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1
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| 1 |
Ki = 7.3 nM
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CP0488032
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(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C33H43N7O9
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1
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| 1 |
Ki = 7.3 nM
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CP0396900
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(S)-4-(4-(4-methoxypiperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H44N6O7
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1
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| 1 |
Ki = 7.4 nM
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CP0494773
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(4-phenyl-6-(4-(pyrrolidin-1-yl)piperidin-1-yl)pyrimidine-2-carboxamido)pentanoic acid
Show/Hide
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C35H49N7O6
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1
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| 1 |
Ki = 7.4 nM
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CP0520409
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(4S)4-{[(4-{[1-(Ethylsulfonyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
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C35H49N5O9S
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1
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| 1 |
Ki = 7.4 nM
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CP0529852
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(S)-4-(6-(4-methylpiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H44N6O6
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1
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| 1 |
Ki = 7.5 nM
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CP0470073
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-((diethylamino)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C36H52N6O6
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1
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| 1 |
Ki = 7.5 nM
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CP0520410
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(4S)-4-({[4-(Aminocarbonyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid
Show/Hide
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C28H35N5O7
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1
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| 1 |
Ki = 7.5 nM
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CP0427013
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(ethylsulfonyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid
Show/Hide
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C33H45N5O9S
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1
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| 1 |
Ki = 7.6 nM
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CP0470909
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(ethoxycarbonyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid
Show/Hide
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C35H47N5O9
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1
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| 1 |
Ki = 7.6 nM
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CP0492725
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(pyrrolidin-1-ylcarbonyl)oxy]pyridin-2-yl}carbonyl)amino]pentanoic Acid
Show/Hide
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C32H41N5O8
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1
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| 1 |
Ki = 7.7 nM
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CP0477009
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butyl 4-[2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]acetyl]piperazine-1-carboxylate
Show/Hide
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C32H43N7O7
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1
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| 1 |
Ki = 7.7 nM
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CP0480982
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(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(2R)-4-ethoxycarbonyl-2-methylpiperazin-1-yl]-5-oxopentanoic acid
Show/Hide
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C34H45N7O9
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1
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| 1 |
Ki = 7.7 nM
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CP0507734
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(S)-4-(4-(4-(methylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H46N6O7
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1
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| 1 |
Ki = 7.9 nM
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CP0514325
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(4S)4-{[(4-Ethoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C29H38N4O7
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1
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| 1 |
Ki = 7.9 nM
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CP0527155
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(4S)-4-{[(4-{[(2-Methoxyethyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C31H41N5O8
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1
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| 1 |
Ki = 7.9 nM
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CP0402203
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3-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-ylamino)propanoic acid
Show/Hide
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C28H29N5O3S
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2
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| 1 |
Ki = 8 nM
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| 2 |
Ki = 122 nM
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CP0372051
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)picolinamido)pentanoic acid
Show/Hide
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C38H54N6O6
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1
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| 1 |
Ki = 8 nM
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CP0501494
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(4S)5-{4-[(Butylamino)carbonothioyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C30H41N5O4S
|
1
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| 1 |
Ki = 8 nM
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CP0439244
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(S)-4-(4-(4-((2-methoxyethoxy)methyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H50N6O8
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1
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| 1 |
Ki = 8.1 nM
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CP0532630
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(S)-4-(4-(4-(2-methoxyethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H48N6O7
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1
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| 1 |
Ki = 8.3 nM
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CP0528068
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(4S)-4-({[4-(4-Methoxybutyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C32H44N4O7
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1
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| 1 |
Ki = 8.3 nM
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CP0071250
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(S)-4-(6-(4-(methoxymethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H46N6O7
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1
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| 1 |
Ki = 8.4 nM
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CP0439243
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(S)-4-(4-(4-(2-methoxyethyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H48N6O7
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1
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| 1 |
Ki = 8.4 nM
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CP0506502
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(S)-4-(4-(4-aminopiperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H43N7O6
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1
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| 1 |
Ki = 8.4 nM
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CP0507733
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(S)-4-(4-(4-(3-(dimethylamino)propyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C36H53N7O6
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1
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| 1 |
Ki = 8.4 nM
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CP0477639
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(4S)4-({[4-(2-Aminoethoxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoicAcid
Show/Hide
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C30H41N5O7
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1
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| 1 |
Ki = 8.4 nM
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CP0502642
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(4S)-4-({[4-(3-Methoxypropyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C31H42N4O7
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1
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| 1 |
Ki = 8.4 nM
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CP0542754
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(S)-4-(4-(4-(2-(dimethylamino)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H51N7O6
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1
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| 1 |
Ki = 8.5 nM
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CP0541363
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(tetrahydro-2H-pyran-4-ylcarbonyl)amino]pyridin-2-yl}carbonyl)amino]pentanoic acid
Show/Hide
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C37H51N5O8
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1
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| 1 |
Ki = 8.5 nM
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CP0492726
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(4S)-4-({[4-(Cyclohexylmethyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H46N4O6
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1
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| 1 |
Ki = 8.6 nM
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CP0522022
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(4S)-4-({[4-({[3-(Dimethylamino)propyl](methyl)amino}carbonyl)-6-phenylpyridin-2-yl]carbonyl}amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H48N6O7
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1
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| 1 |
Ki = 8.6 nM
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CP0502243
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(4S)4-({[4-(2-Aminoethoxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid
Show/Hide
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C29H39N5O7
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1
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| 1 |
Ki = 8.8 nM
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CP0470071
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(S)-4-(4-(4-(2-(methylsulfonyl)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H48N6O8S
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1
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| 1 |
Ki = 8.9 nM
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CP0477640
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}-amino)pentanoic Acid
Show/Hide
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C36H50N6O6
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1
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| 1 |
Ki = 9 nM
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CP0502644
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(4S)5-{4-[(Ethylamino)carbonothioyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C28H37N5O4S
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1
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| 1 |
Ki = 9 nM
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CP0447512
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(trifluoroacetyl)amino]pyridin-2-yl}carbonyl)amino]pentanoic acid
Show/Hide
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C33H42F3N5O7
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1
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| 1 |
Ki = 9.1 nM
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CP0383767
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(4S)4-{[(4-{[(4-Methoxypiperidin-1-yl)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C38H54N6O8
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1
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| 1 |
Ki = 9.2 nM
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CP0039796
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(S)-4-(4-(4-(aminomethyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H45N7O6
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1
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| 1 |
Ki = 9.4 nM
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CP0498879
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(S)-4-(6-(1-isopropylpiperidin-4-ylamino)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H49N7O6
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1
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| 1 |
Ki = 9.4 nM
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CP0522023
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(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-({[6-phenyl-4-(piperidin-4-yloxy)yridin-2-yl]carbonyl}amino)entanoicAcid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 9.4 nM
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CP0522024
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-{[1-(2-methoxyethyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid
Show/Hide
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C34H47N5O8
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1
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| 1 |
Ki = 9.4 nM
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CP0421639
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(4S)4-[({4-[(2-Methoxyethyl)mino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid
Show/Hide
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C30H41N5O7
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1
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| 1 |
Ki = 9.8 nM
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CP0532618
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(4S)-4-(4-(3-(acetamidomethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H48N6O7
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1
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| 1 |
Ki = 9.9 nM
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CP0384073
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(4S)4-{[(4-{[1-(2-Methoxyethyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
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C35H49N5O8
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1
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| 1 |
Ki = 9.9 nM
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CP0455420
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(4S)4-({[4-(2-Methoxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C30H40N4O8
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2
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| 1 |
Ki = 9.9 nM
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| 2 |
Ki = 10 nM
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CP0531199
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(S)-4-(4-(4-(2-hydroxyethoxy)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H46N6O8
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1
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| 1 |
Ki = 10 nM
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CP0372043
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(4S)-5-oxo-4-(4-(3-((2-oxopyrrolidin-1-yl)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C37H50N6O7
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1
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| 1 |
Ki = 10 nM
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CP0421989
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-(pyrrolidine-1-carbonyl)piperazin-1-yl)picolinamido)pentanoic acid
Show/Hide
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C36H49N7O7
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1
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| 1 |
Ki = 10 nM
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CP0402062
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(4S)4-({[4-(4-Aminopiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
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C29H38N6O6
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2
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| 1 |
Ki = 10 nM
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| 2 |
Ki = 27 nM
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CP0402063
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(4S)-4-[({4-[(Methylamino)carbonyl]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C29H37N5O7
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1
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| 1 |
Ki = 10 nM
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CP0514326
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(tetrahydro-2H-pyran-4-yloxy)yridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
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C31H40N4O8
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1
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| 1 |
Ki = 10 nM
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CP0514327
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(1-isopropylpiperidin-4-yl)xy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C34H47N5O7
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1
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| 1 |
Ki = 10 nM
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CP0519066
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]methoxy}pyridin-2-yl)carbonyl]-amino}pentanoic Acid
Show/Hide
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C34H42F3N5O8
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1
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| 1 |
Ki = 10 nM
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CP0519069
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(4S)4-({[4-(4-Morpholin-4-ylpiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C36H50N6O7
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1
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| 1 |
Ki = 10 nM
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CP0494758
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(S)-4-(6-(4-(2-methoxyethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H48N6O7
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1
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| 1 |
Ki = 10.2 nM
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CP0439750
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C27H34N4O6
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1
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| 1 |
Ki = 11 nM
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CP0510214
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(4S)4-({[4-(4-Hydroxypiperidin-1-yl)6-phenylpyridin-2-yl]-carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid
Show/Hide
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C32H43N5O7
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1
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| 1 |
Ki = 11 nM
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CP0424414
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(S)-4-(4-(4-((ethylamino)methyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H49N7O6
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1
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| 1 |
Ki = 11 nM
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CP0424415
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(S)-4-(4-morpholino-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C30H40N6O7
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1
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| 1 |
Ki = 11 nM
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CP0488875
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(S)-4-(4-(4-((methylamino)methyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H47N7O6
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1
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| 1 |
Ki = 11 nM
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CP0488879
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-(piperidin-4-yloxy)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
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C30H40N6O7
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1
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| 1 |
Ki = 11 nM
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CP0494777
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(S)-4-(4-(4-methylpiperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H43N7O6
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1
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| 1 |
Ki = 11 nM
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CP0502771
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(S)-4-(4-(3-morpholinopropoxy)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H46N6O8
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1
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| 1 |
Ki = 11 nM
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CP0372052
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(S)-4-(4-(4-(2-methoxyethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H49N5O7
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1
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| 1 |
Ki = 11 nM
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CP0532621
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(4S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(3-(pyrrolidin-1-yl)piperidin-1-yl)picolinamido)pentanoic acid
Show/Hide
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C36H50N6O6
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1
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| 1 |
Ki = 11 nM
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CP0427021
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(piperidin-1-ylcarbonyl)oxy]pyridin-2-yl}carbonyl)mino]-pentanoic Acid
Show/Hide
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C33H43N5O8
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1
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| 1 |
Ki = 11 nM
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CP0469876
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(4S)4-[({4-[(Ethoxycarbonyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C34H47N5O8
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1
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| 1 |
Ki = 11 nM
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CP0477641
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)yridin-2-yl]carbonyl}-amino)entanoic Acid
Show/Hide
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C32H42N4O8
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1
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| 1 |
Ki = 11 nM
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CP0514328
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(4S)4-{[(4-Hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C27H34N4O7
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1
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| 1 |
Ki = 11 nM
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CP0522026
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(4S)4-{[(4-{[1-(Methoxyacetyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H47N5O8
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1
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| 1 |
Ki = 11 nM
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CP0522027
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(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-[({4-[(2-methoxyethyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C31H43N5O7
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1
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| 1 |
Ki = 11 nM
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CP0522030
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(4S)-5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(propylamino)carbonyl]pyridin-2-yl}carbonyl)amino]-pentanoic Acid
Show/Hide
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C31H41N5O7
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1
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| 1 |
Ki = 11 nM
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CP0522032
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(4S)-4-{[(4-{[Methyl(1-methylpiperidin-4-yl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)-carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C35H48N6O7
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1
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| 1 |
Ki = 11 nM
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CP0528069
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-2-ylmethoxy)yridin-2-yl]carbonyl}amino)entanoic Acid
Show/Hide
|
C32H43N5O7
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1
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| 1 |
Ki = 11 nM
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CP0513926
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-4-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid
Show/Hide
|
C31H41N5O7
|
1
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| 1 |
Ki = 12 nM
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CP0089675
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(S)-4-(4-(4-(methoxymethyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H46N6O7
|
1
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| 1 |
Ki = 12 nM
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CP0529860
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(S)-4-(4-((1-methylpiperidin-4-yl)methoxy)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H46N6O7
|
1
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| 1 |
Ki = 12 nM
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CP0537587
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(2-methoxyethoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
|
C28H37N5O8
|
1
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| 1 |
Ki = 12 nM
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CP0541516
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(S)-4-(4-(4-(2-methoxyethyl)piperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H47N7O7
|
1
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| 1 |
Ki = 12 nM
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CP0372046
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(S)-4-(4-(4-(diethylcarbamoyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C36H51N7O7
|
1
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| 1 |
Ki = 12 nM
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CP0383891
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(S)-4-(4-(4-(2-(dimethylamino)ethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C36H52N6O6
|
1
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| 1 |
Ki = 12 nM
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CP0498714
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(S)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(propoxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C35H48N6O7
|
1
|
| 1 |
Ki = 12 nM
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CP0421677
|
4S)4-{[(4-{[1-(Methoxyacetyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
Show/Hide
|
C36H49N5O9
|
1
|
| 1 |
Ki = 12 nM
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CP0477642
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(propylamino)pyridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
|
C30H41N5O6
|
1
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| 1 |
Ki = 12 nM
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CP0513927
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(4S)-4-[({4-[3-(Isobutylamino)propyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C34H49N5O6
|
1
|
| 1 |
Ki = 12 nM
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CP0522034
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]oxy}pyridin-2-yl)carbonyl]-amino}pentanoic Acid
Show/Hide
|
C33H40F3N5O8
|
1
|
| 1 |
Ki = 12 nM
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CP0470072
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(S)-4-(4-(4-(2-hydroxyethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H46N6O7
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1
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| 1 |
Ki = 13 nM
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CP0513907
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4-(4-(3-hydroxypyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H41N5O7
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1
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| 1 |
Ki = 13 nM
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CP0519074
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(4S)-4-[({4-[(Ethylamino)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C30H39N5O7
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1
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| 1 |
Ki = 13 nM
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CP0431499
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(4S)4-[({4-[4-(Aminomethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoicAcid
Show/Hide
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C30H40N6O6
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1
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| 1 |
Ki = 14 nM
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CP0492797
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(4S)5-{4-[(Octyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C30H40N4O6
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1
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| 1 |
Ki = 14 nM
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CP0529855
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(S)-4-(4-(4-(dimethylcarbamoyl)piperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H46N8O7
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1
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| 1 |
Ki = 14 nM
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CP0519076
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(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-({[4-(2-methoxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
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C31H42N4O8
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1
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| 1 |
Ki = 14 nM
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CP0140474
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AR-C126532XX
Show/Hide
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C23H28F2N6O4S
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1
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| 1 |
Ki = 14 nM
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CP0489633
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(S)-4-(4,6-diphenylpicolinamido)-5-oxo-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid
Show/Hide
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C30H32N4O6
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1
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| 1 |
Ki = 15 nM
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CP0545695
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(S)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H43N5O8S
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1
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| 1 |
Ki = 15 nM
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CP0514381
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-((1-methylpiperidin-4-yl)methoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
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C32H44N6O7
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1
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| 1 |
Ki = 15 nM
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CP0381097
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(4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H47N5O7
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1
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| 1 |
Ki = 15 nM
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CP0533227
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(S)-4-(4-(4-methylpiperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H44N6O6
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1
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| 1 |
Ki = 15 nM
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CP0502670
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(4S)4-{[(4,6-Diphenylpyridin-2-yl)carbonyl]amino}-5-[4-(ethoxycarbonyl)iperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
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C30H32N4O6
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1
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| 1 |
Ki = 15 nM
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CP0513928
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(4S)4-({[4-(4-Methoxypiperidin-1-yl)6-phenylpyridin-2-yl]-carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 15 nM
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CP0522039
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(4S)5-{4-[(2-Cyclopropylethoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C27H32N4O6
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1
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| 1 |
Ki = 15 nM
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CP0514383
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-(piperidin-4-ylmethoxy)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
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C31H42N6O7
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1
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| 1 |
Ki = 16 nM
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CP0372045
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(S)-4-(4-((R)-3-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H43N5O7
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1
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| 1 |
Ki = 16 nM
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CP0383854
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(S)-4-(4-(4-isobutyrylpiperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H48N6O7
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1
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| 1 |
Ki = 16 nM
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CP0405504
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(S)-4-(6-(cyclopentylthio)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H41N5O6S
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1
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| 1 |
Ki = 17 nM
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CP0522019
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(4S)-4-(4-(3-carbamoylpiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H44N6O7
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1
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| 1 |
Ki = 17 nM
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CP0519079
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(4S)4-({[4-(4-Aminopiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid
Show/Hide
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C32H44N6O6
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1
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| 1 |
Ki = 17 nM
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CP0489634
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(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(methoxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C31H41N5O7
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1
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| 1 |
Ki = 18 nM
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CP0505736
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(4S)4-[({4-[4-(Aminomethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoic Acid
Show/Hide
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C34H48N6O6
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1
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| 1 |
Ki = 18 nM
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CP0509344
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(2-methoxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
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C29H38N4O8
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1
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| 1 |
Ki = 18 nM
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CP0401972
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(S)-4-(4-((S)-3-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H43N5O7
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1
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| 1 |
Ki = 18 nM
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CP0421678
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-propoxypyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C30H40N4O7
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1
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| 1 |
Ki = 18 nM
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CP0520521
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(4,4,4-trifluorobutoxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C26H29F3N4O6
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1
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| 1 |
Ki = 18 nM
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CP0528070
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(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-({[4-(2-hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
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C30H40N4O8
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1
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| 1 |
Ki = 18 nM
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CP0374052
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(R)-biphenyl-4-yl(4-(2-(2,3-dihydroxypropylamino)-6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)methanone
Show/Hide
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C28H31N5O3S
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2
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| 1 |
Ki = 19 nM
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| 2 |
Ki = 75 nM
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CP0494779
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(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(1-isopropylpiperidin-4-yloxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
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C33H46N6O7
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1
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| 1 |
Ki = 19 nM
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CP0502769
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(S)-4-(4-(cyclopentylmethylamino)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C31H43N7O6
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1
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| 1 |
Ki = 19 nM
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CP0522062
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]oxy}pyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C34H42F3N5O8
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1
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| 1 |
Ki = 19 nM
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CP0413946
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(4S)-4-[[5-[2-[(2S)-2-(cyclobutylmethylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C34H45N7O9
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1
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| 1 |
Ki = 19 nM
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CP0402066
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(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(2-hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid
Show/Hide
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C28H36N4O8
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2
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| 1 |
Ki = 20 nM
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| 2 |
Ki = 21 nM
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CP0514329
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(ethoxycarbonyl)iperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid
Show/Hide
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C34H45N5O9
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1
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| 1 |
Ki = 20 nM
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CP0526321
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(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-{[(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
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C28H36N4O7
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1
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| 1 |
Ki = 20 nM
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CP0534169
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(4S)-4-[[5-[2-[(2S)-2-(cyclopentylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C34H45N7O9
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1
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| 1 |
Ki = 20 nM
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CP0372042
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4-(4-(3-(hydroxymethyl)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H43N5O7
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1
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| 1 |
Ki = 21 nM
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CP0439239
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(2,2,2-trifluoroethylthio)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
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C28H34F3N5O6S
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1
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| 1 |
Ki = 22 nM
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CP0529856
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(4-phenyl-6-(piperazin-1-yl)pyrimidine-2-carboxamido)pentanoic acid
Show/Hide
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C30H41N7O6
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1
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| 1 |
Ki = 22 nM
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CP0452728
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(4S)-4-(4-(3-(methoxymethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C34H47N5O7
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1
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| 1 |
Ki = 22 nM
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CP0470070
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(S)-4-(4-(4-acetylpiperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C33H44N6O7
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1
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| 1 |
Ki = 22 nM
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CP0502671
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(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[4-(propoxymethyl)piperidin-1-yl]pyridin-2-yl}carbonyl)amino]pentanoic Acid
Show/Hide
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C36H51N5O7
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1
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| 1 |
Ki = 22 nM
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CP0513929
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(4S)4-[({4-[4-(Dimethylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H48N6O6
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1
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| 1 |
Ki = 22 nM
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CP0513930
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(4S)-4-[({4-[3-(Diethylamino)propyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C34H49N5O6
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1
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| 1 |
Ki = 22 nM
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CP0565821
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(4S)-5-[4-(butoxycarbonylamino)piperidin-1-yl]-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
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C36H49N7O9
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1
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| 1 |
Ki = 22 nM
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CP0431500
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(S)-4-(4-(diethylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C28H37N5O6
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1
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| 1 |
Ki = 23 nM
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CP0488003
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ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-(methanesulfonamido)butanoyl]piperazine-1-carboxylate
Show/Hide
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C33H46N8O9S
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1
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| 1 |
Ki = 23 nM
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CP0523454
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ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-hydroxybutanoyl]piperazine-1-carboxylate
Show/Hide
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C32H43N7O8
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1
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| 1 |
Ki = 23 nM
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CP0534172
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ELINOGREL
Show/Hide
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C20H15ClFN5O5S2
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1
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| 1 |
Ki = 23 nM
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CP0524030
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(S)-5-(4-(hexyloxycarbonyl)piperazin-1-yl)-4-(4-(4-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C33H45N5O7
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1
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| 1 |
Ki = 24 nM
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CP0532610
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(4S)-4-[[4-[(3R)-3-(dimethylcarbamoyl)pyrrolidin-1-yl]-6-phenylpyridine-2-carbonyl]amino]-5-oxo-5-(4-pentoxycarbonylpiperazin-1-yl)pentanoic acid
Show/Hide
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C34H46N6O7
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1
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| 1 |
Ki = 24 nM
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CP0498718
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(S)-4-(4-(4-(acetamidomethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C35H48N6O7
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1
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| 1 |
Ki = 25 nM
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CP0538545
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(4S)4-[({4-[(Methoxyacetyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C34H47N5O8
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1
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| 1 |
Ki = 25 nM
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CP0485240
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(S)-4-(4-(benzylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C31H35N5O6
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1
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| 1 |
Ki = 26 nM
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CP0502339
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(4S)-4-(4-(3-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C37H52N6O7
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1
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| 1 |
Ki = 26 nM
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CP0532612
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(4S)-4-[[4-[(3S)-3-(dimethylcarbamoyl)pyrrolidin-1-yl]-6-phenylpyridine-2-carbonyl]amino]-5-oxo-5-(4-pentoxycarbonylpiperazin-1-yl)pentanoic acid
Show/Hide
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C34H46N6O7
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1
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| 1 |
Ki = 26 nM
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CP0384078
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-[4-(propoxycarbonyl)iperazin-1-yl]pentanoic Acid
Show/Hide
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C25H30N4O6
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1
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| 1 |
Ki = 27 nM
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CP0374051
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[4-[6-ethyl-2-(3-hydroxyazetidin-1-yl)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]-(4-phenylphenyl)methanone
Show/Hide
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C28H29N5O2S
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2
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| 1 |
Ki = 27 nM
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| 2 |
Ki = 297 nM
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CP0501055
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(S)-4-(6-(2-(diethylamino)ethoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H46N6O7
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1
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| 1 |
Ki = 27 nM
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CP0376803
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(4S)-4-[[5-[2-[(2S)-2-[cyclobutyl(methyl)carbamoyl]pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C34H45N7O9
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1
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| 1 |
Ki = 27 nM
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CP0404884
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(S)-4-(4-(benzyloxy)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C31H34N4O7
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1
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| 1 |
Ki = 28 nM
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CP0421646
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(4S)5-{4-[(Cyclobutylmethoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C27H32N4O6
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1
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| 1 |
Ki = 28 nM
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CP0421648
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(4S)4-({[4-(Benzyloxy)6-phenylpyridin-2-yl]carbonyl}amino)5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
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C31H34N4O7
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1
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| 1 |
Ki = 28 nM
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CP0505737
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(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C26H32N4O6
|
1
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| 1 |
Ki = 29 nM
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CP0452578
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[4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]-(4-phenylphenyl)methanone
Show/Hide
|
C25H24N4OS
|
1
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| 1 |
Ki = 29 nM
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CP0415571
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(S)-4-(4-(4-acetylpiperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C32H43N7O7
|
1
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| 1 |
Ki = 29 nM
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CP0401974
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(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-propylpiperazin-1-yl)picolinamido)pentanoic acid
Show/Hide
|
C34H48N6O6
|
1
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| 1 |
Ki = 29 nM
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CP0413943
|
(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[4-(3-methoxyphenyl)piperazin-1-yl]-5-oxopentanoic acid
Show/Hide
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C37H45N7O8
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0455310
|
1-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)piperidine-3-carboxamide
Show/Hide
|
C31H34N6O2S
|
2
|
| 1 |
Ki = 31 nM
|
|
|
| 2 |
Ki = 203 nM
|
|
|
|
CP0441473
|
(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(4-phenyl-6-(piperidin-4-ylmethoxy)pyrimidine-2-carboxamido)pentanoic acid
Show/Hide
|
C32H44N6O7
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0373535
|
4-(4-(3-(methoxymethyl)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H45N5O7
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0498703
|
(4S)-4-(4-(3-methoxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C33H45N5O7
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0489635
|
(4S)4-({[4-(2-Hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid
Show/Hide
|
C29H38N4O8
|
2
|
| 1 |
Ki = 31 nM
|
|
|
| 2 |
Ki = 32 nM
|
|
|
|
CP0513935
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoicAcid
Show/Hide
|
C26H32N4O7
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0520475
|
(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-[({4-[4-(methoxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
|
C35H49N5O7
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0491191
|
(4S)5-{4-[(3-Methylbutoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C27H34N4O6
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0376802
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-phenylpyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C34H40N6O8
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0481518
|
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
|
C33H44N6O6
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0485242
|
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-({[4-(methylamino)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid
Show/Hide
|
C25H31N5O6
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0447582
|
[4-[6-ethyl-2-(3-hydroxypyrrolidin-1-yl)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]-(4-phenylphenyl)methanone
Show/Hide
|
C29H31N5O2S
|
2
|
| 1 |
Ki = 35 nM
|
|
|
| 2 |
Ki = 241 nM
|
|
|
|
CP0491247
|
(S)-4-(4-(1-isopropylpiperidin-4-ylamino)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C34H49N7O6
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0439752
|
(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-butoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
|
C30H40N4O7
|
2
|
| 1 |
Ki = 35 nM
|
|
|
| 2 |
Ki = 36 nM
|
|
|
|
CP0485243
|
(S)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxo-5-(4-(hexyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C32H45N5O8S
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0457546
|
3-(3-(6-ethyl-4-(4-isobutyrylpiperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
|
C20H28N6O4S
|
2
|
| 1 |
Ki = 36 nM
|
|
|
| 2 |
Ki = 46 nM
|
|
|
|
CP0401572
|
3-(3-(6-ethyl-4-(4-(5-phenylpicolinoyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
|
C28H29N7O4S
|
2
|
| 1 |
Ki = 37 nM
|
|
|
| 2 |
Ki = 161 nM
|
|
|
|
CP0415689
|
[4-[6-ethyl-2-(2-hydroxyethylamino)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]-(4-phenylphenyl)methanone
Show/Hide
|
C27H29N5O2S
|
2
|
| 1 |
Ki = 37 nM
|
|
|
| 2 |
Ki = 163 nM
|
|
|
|
CP0498880
|
(S)-4-(4-(3-(dimethylamino)propylamino)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C31H45N7O6
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0502641
|
(4S)4-{[(4-Butoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-[4-(ethoxycarbonyl)iperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
|
C28H36N4O7
|
2
|
| 1 |
Ki = 39 nM
|
|
|
| 2 |
Ki = 60 nM
|
|
|
|
CP0470110
|
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-morpholin-4-yl-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
|
C28H35N5O7
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0439753
|
(S)-5-(4-((2-cyclopentylethoxy)carbonyl)piperazin-1-yl)-4-(4-(4-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
|
C34H45N5O7
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0565820
|
(4S)-5-(4-benzoylpiperidin-1-yl)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C38H44N6O8
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0523457
|
(4S)-4-[[5-[2-[(2S)-2-(tert-butylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C33H45N7O9
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0421649
|
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-({[4-(4-hydroxypiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
|
C29H37N5O7
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0473834
|
(S)-4-(6-(tert-butylthio)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C30H41N5O6S
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0502643
|
(4S)5-{4-[(3,3-Dimethylbutoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C28H36N4O6
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0541364
|
(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(propylamino)carbonothioyl]piperazin-1-yl}pentanoic acid
Show/Hide
|
C29H39N5O4S
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0376801
|
ethyl 4-[(2S)-4-acetamido-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]butanoyl]piperazine-1-carboxylate
Show/Hide
|
C34H46N8O8
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0500038
|
(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)azetidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C32H41N7O9
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0383988
|
(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C28H36N4O6
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0499358
|
(4S)4-({[4-({[4-(Methoxymethyl)piperidin-1-yl]carbonyl}amino)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
|
C39H56N6O8
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0514338
|
(4S)5-{4-[(Cyclohexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C28H34N4O6
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0383989
|
(4S)4-({[4-({[Methyl(tetrahydro-2H-pyran-4-ylmethyl)mino]-carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C35H47N5O9
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0514339
|
(4S)4-({[4-(Dimethylamino)6-phenylpyridin-2-yl]carbonyl}-amino)5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
|
C26H33N5O6
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0514340
|
(4S)4-({[4-(Dipropylamino)6-phenylpyridin-2-yl]carbonyl}-amino)5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
|
C30H41N5O6
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0489116
|
(4S)5-{4-[(Cyclopentylmethoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C28H34N4O6
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0439260
|
(S)-4-(4-(4-(2-(dimethylamino)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C32H45N7O6
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0383990
|
(4S)5-{4-[(Cyclopentyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C27H32N4O6
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0439754
|
(S)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
|
C28H37N5O8S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0476884
|
ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-3-(methanesulfonamido)propanoyl]piperazine-1-carboxylate
Show/Hide
|
C32H44N8O9S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0428925
|
(4S)4-{[(4-Butoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
|
C31H42N4O7
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0523455
|
(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(3R)-4-ethoxycarbonyl-3-methylpiperazin-1-yl]-5-oxopentanoic acid
Show/Hide
|
C34H45N7O9
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0489117
|
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(hydroxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
|
C30H39N5O7
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0541365
|
(4S)5-{4-[(Hexylamino)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
|
C32H45N5O5
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0480981
|
(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(2S)-4-ethoxycarbonyl-2-methylpiperazin-1-yl]-5-oxopentanoic acid
Show/Hide
|
C34H45N7O9
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0529861
|
(4S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-((tetrahydrofuran-2-yl)methoxy)pyrimidine-4-carboxamido)pentanoic acid
Show/Hide
|
C30H39N5O8
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0501495
|
(4S)5-Oxo-5-{4-[(pentylamino)carbonyl]piperazin-1-yl}-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
|
C31H43N5O5
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0413944
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(5-methyl-1H-imidazol-2-yl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C32H40N8O8
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0413945
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(piperidine-1-carbonyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C34H45N7O9
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0553487
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(propan-2-ylcarbamoyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C32H43N7O9
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0513937
|
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
|
C24H28N4O7
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0497468
|
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(propylamino)pyridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
|
C27H35N5O6
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0507705
|
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
|
C35H48N6O6
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0376805
|
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(propylcarbamoyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C32H43N7O9
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0421650
|
(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-4-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid
Show/Hide
|
C29H37N5O7
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0439267
|
(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(3-hydroxypropoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid
Show/Hide
|
C27H34N4O8
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0457545
|
3-(3-(4-(4-(2-(3,4-difluorophenyl)acetyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
|
C24H26F2N6O4S
|
2
|
| 1 |
Ki = 68 nM
|
|
|
| 2 |
Ki = 140 nM
|
|
|
|
CP0545720
|
(S)-4-(4-(4-(aminomethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-(4-((2-cyclopentylethoxy)carbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
|
C35H48N6O6
|
1
|
| 1 |
Ki = 69 nM
|
|
|
|
CP0514341
|
(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(3-methoxypropoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
|
C28H36N4O8
|
1
|
| 1 |
Ki = 69 nM
|
|
|
|
CP0439238
|
(S)-4-(6-(cyclohexylthio)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
|
C32H43N5O6S
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0381619
|
(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxo-5-(4-phenoxycarbonylpiperazin-1-yl)pentanoic acid
Show/Hide
|
C37H43N7O9
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0427127
|
(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(2-(diethylamino)ethoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
|
C31H44N6O7
|
1
|
| 1 |
Ki = 72 nM
|
|
|
|
CP0439268
|
(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-4-ylmethoxy)pyridin-2-yl]carbonyl}amino)pentanoic Acid
Show/Hide
|
C30H39N5O7
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0373277
|
[4-[6-ethyl-2-(3-hydroxypropylamino)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]-(4-phenylphenyl)methanone
Show/Hide
|
C28H31N5O2S
|
2
|
| 1 |
Ki = 78 nM
|
|
|
| 2 |
Ki = 441 nM
|
|
|
|
CP0421651
|
(4S)5-{4-[(But-3-yn-1-yloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C26H28N4O6
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0389568
|
(S)-5-(4-((2-cyclopentylethoxy)carbonyl)piperazin-1-yl)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C33H45N5O8S
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1
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| 1 |
Ki = 80 nM
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CP0507228
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(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(3S)-4-ethoxycarbonyl-3-methylpiperazin-1-yl]-5-oxopentanoic acid
Show/Hide
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C34H45N7O9
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1
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| 1 |
Ki = 80 nM
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CP0517539
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(4S)-4-(4-(1-(diethylamino)-1-oxobutan-2-yloxy)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C32H43N5O8
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1
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| 1 |
Ki = 81 nM
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CP0482445
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(4S)-5-[3-(butoxycarbonylamino)pyrrolidin-1-yl]-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
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C35H47N7O9
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1
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| 1 |
Ki = 82 nM
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CP0261352
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[4-(1-ethoxy-2-methyl-1-oxopropan-2-yl)oxy-7-methylquinoline-2-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
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C29H38N4O9
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1
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| 1 |
Ki = 86 nM
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CP0383992
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(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-[({4-[(2-hydroxyethyl)methyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C27H35N5O7
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1
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| 1 |
Ki = 87 nM
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CP0421652
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(4S)4-{[(4-Butoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoic Acid
Show/Hide
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C32H44N4O7
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1
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| 1 |
Ki = 89 nM
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CP0383995
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(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(2-methoxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
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C27H34N4O8
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2
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| 1 |
Ki = 92 nM
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| 2 |
Ki = 140 nM
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CP0506292
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(S)-5-(4-(allyloxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(piperidin-4-yloxy)picolinamido)pentanoic acid
Show/Hide
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C30H37N5O7
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1
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| 1 |
Ki = 93 nM
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CP0477670
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(2,2,2-trifluoroethoxy)carbonyl]piperazin-1-yl}pentanoic Acid
Show/Hide
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C24H25F3N4O6
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1
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| 1 |
Ki = 94 nM
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CP0477671
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(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-ethoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
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C26H32N4O7
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1
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| 1 |
Ki = 94 nM
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CP0502251
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(S)-5-(4-(allyloxycarbonyl)piperazin-1-yl)-4-(4-(2-methoxyethoxy)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C28H34N4O8
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1
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| 1 |
Ki = 95 nM
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CP0383994
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(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-methoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
Show/Hide
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C25H30N4O7
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1
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| 1 |
Ki = 96 nM
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CP0492622
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(S)-5-(4-(allyloxycarbonyl)piperazin-1-yl)-4-(4-butoxy-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C29H36N4O7
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1
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| 1 |
Ki = 99 nM
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CP0506293
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(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-[({4-[(2-methoxyethyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C27H35N5O7
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1
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| 1 |
Ki = 99 nM
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CP0376804
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(4S)-4-[[5-[2-[(2S)-2-(cyclopropylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C32H41N7O9
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1
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| 1 |
Ki = 105 nM
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CP0527186
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ethyl 4-[2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]acetyl]piperazine-1-carboxylate
Show/Hide
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C30H39N7O7
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1
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| 1 |
Ki = 107 nM
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CP0513074
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ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]propanoyl]piperazine-1-carboxylate
Show/Hide
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C31H41N7O7
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1
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| 1 |
Ki = 111 nM
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CP0470941
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(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-piperidin-1-ylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C29H37N5O6
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1
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| 1 |
Ki = 112 nM
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CP0481512
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(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-[({4-[(2-hydroxyethyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
Show/Hide
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C26H33N5O7
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2
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| 1 |
Ki = 114 nM
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| 2 |
Ki = 117 nM
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CP0520478
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(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-propoxypyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C27H34N4O7
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1
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| 1 |
Ki = 120 nM
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CP0441472
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(4S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(1-(diethylamino)-1-oxobutan-2-yloxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid
Show/Hide
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C33H46N6O8
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1
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| 1 |
Ki = 123 nM
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CP0485777
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naphthalen-1-yl 4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazine-1-carboxylate
Show/Hide
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C23H22N4O2S
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1
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| 1 |
Ki = 130 nM
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CP0413942
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(4S)-5-(4-benzoylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
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C37H43N7O8
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1
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| 1 |
Ki = 130 nM
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CP0520479
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(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(4-hydroxybutoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
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C28H36N4O8
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1
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| 1 |
Ki = 132 nM
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CP0500086
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(4S)-4-[[5-(1-ethoxycarbonylcyclobutyl)oxy-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C29H37N5O9
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1
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| 1 |
Ki = 139 nM
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CP0439269
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(S)-4-(4-(2-hydroxyethoxy)-6-phenylpicolinamido)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C27H34N4O8
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1
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| 1 |
Ki = 145 nM
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CP0545721
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(S)-4-(4-butoxy-6-phenylpicolinamido)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C29H38N4O7
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1
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| 1 |
Ki = 146 nM
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CP0492623
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(S)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(piperidin-4-yloxy)picolinamido)pentanoic acid
Show/Hide
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C30H39N5O7
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1
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| 1 |
Ki = 157 nM
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CP0514342
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(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(2-hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid
Show/Hide
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C26H32N4O8
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1
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| 1 |
Ki = 157 nM
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CP0374050
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3-(3-(6-ethyl-4-(4-(3,3,3-trifluoropropanoyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
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C19H23F3N6O4S
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2
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| 1 |
Ki = 172 nM
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| 2 |
Ki = 177 nM
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CP0565819
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ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoyl]piperazine-1-carboxylate
Show/Hide
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C33H45N7O7
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1
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| 1 |
Ki = 172 nM
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CP0500039
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-(2-oxopyrrolidin-1-yl)ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
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C28H34N6O9
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1
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| 1 |
Ki = 173 nM
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CP0488002
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ethyl 4-[(2S)-4-amino-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]butanoyl]piperazine-1-carboxylate
Show/Hide
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C32H44N8O7
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1
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| 1 |
Ki = 180 nM
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CP0507226
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ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-3-methylbutanoyl]piperazine-1-carboxylate
Show/Hide
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C33H45N7O7
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1
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| 1 |
Ki = 183 nM
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CP0506504
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(S)-4-(4-(2-(diethylamino)ethoxy)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
Show/Hide
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C32H46N6O7
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1
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| 1 |
Ki = 184 nM
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CP0517540
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(S)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-4-(4-(2-methoxyethoxy)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C28H36N4O8
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1
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| 1 |
Ki = 189 nM
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CP0389569
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(S)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(piperidin-4-ylmethylamino)picolinamido)pentanoic acid
Show/Hide
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C30H40N6O6
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1
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| 1 |
Ki = 190 nM
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CP0383618
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3-(3-(6-ethyl-4-(4-(2-(3-methoxyphenoxy)acetyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
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C25H30N6O6S
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2
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| 1 |
Ki = 191 nM
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| 2 |
Ki = 447 nM
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CP0523456
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(4S)-5-[(1-butoxycarbonylpyrrolidin-3-yl)amino]-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
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C35H47N7O9
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1
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| 1 |
Ki = 193 nM
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CP0536748
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(4S)5-{4-[(Benzyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C29H30N4O6
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1
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| 1 |
Ki = 196 nM
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CP0452747
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ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-6-hydroxyhexanoyl]piperazine-1-carboxylate
Show/Hide
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C34H47N7O8
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1
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| 1 |
Ki = 202 nM
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CP0534825
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(S)-5-(4-(allyloxycarbonyl)piperazin-1-yl)-4-(4-(2-hydroxyethoxy)-6-phenylpicolinamido)-5-oxopentanoic acid
Show/Hide
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C27H32N4O8
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1
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| 1 |
Ki = 203 nM
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CP0565818
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ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-methylpentanoyl]piperazine-1-carboxylate
Show/Hide
|
C34H47N7O7
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1
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| 1 |
Ki = 207 nM
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CP0389581
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(S)-5-oxo-4-(6-phenylpicolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid
Show/Hide
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C24H28N4O6
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1
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| 1 |
Ki = 209 nM
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CP0520480
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(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoicAcid
Show/Hide
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C24H28N4O6
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1
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| 1 |
Ki = 209 nM
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CP0447580
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3-(3-(6-ethyl-4-(4-(3-phenoxypropanoyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
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C25H30N6O5S
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2
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| 1 |
Ki = 213 nM
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| 2 |
Ki = 783 nM
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CP0492670
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(S)-4-(4-(3-aminopropoxy)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C27H35N5O7
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1
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| 1 |
Ki = 214 nM
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CP0507229
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C33H43N7O9
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1
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| 1 |
Ki = 219 nM
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CP0498740
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3-(3-(6-ethyl-4-(4-(2-phenylacetyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
|
C24H28N6O4S
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2
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| 1 |
Ki = 223 nM
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| 2 |
Ki = 231 nM
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CP0544459
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(4S)-4-[[5-[2-[3-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C33H43N7O9
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1
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| 1 |
Ki = 238 nM
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CP0401571
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(4-(2-(4-aminopiperidin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)(biphenyl-4-yl)methanone
Show/Hide
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C30H34N6OS
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2
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| 1 |
Ki = 240 nM
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| 2 |
Ki = 325 nM
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CP0413947
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(4S)-4-[[5-(3,3-dimethyl-2-oxobutoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C28H37N5O8
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1
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| 1 |
Ki = 242 nM
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CP0544461
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(4S)-4-[[5-(2-cyclopropyl-2-oxoethoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C27H33N5O8
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1
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| 1 |
Ki = 249 nM
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CP0509310
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(S)-4-(4-(2-(dimethylamino)ethylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C28H38N6O6
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1
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| 1 |
Ki = 270 nM
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CP0526316
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(propylamino)carbonyl]piperazin-1-yl}pentanoic acid
Show/Hide
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C29H39N5O5
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1
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| 1 |
Ki = 277 nM
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CP0383996
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(4S)5-[4-(Isopropoxycarbonyl)iperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
|
C25H30N4O6
|
1
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| 1 |
Ki = 280 nM
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CP0544460
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(4S)-4-[[5-[2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C29H37N7O9
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1
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| 1 |
Ki = 283 nM
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CP0541366
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(4S)5-{4-[(Ethylamino)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
|
C28H37N5O5
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1
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| 1 |
Ki = 288 nM
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CP0485325
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3-(3-(6-ethyl-4-(4-propionylpiperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
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C19H26N6O4S
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2
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| 1 |
Ki = 295 nM
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| 2 |
Ki = 367 nM
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CP0525479
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
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C31H41N7O9
|
1
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| 1 |
Ki = 303 nM
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CP0470942
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(4S)4-({[4-(2-Aminoethoxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-[4-(ethoxycarbonyl)iperazin-1-yl]-5-oxopentanoicAcid
Show/Hide
|
C26H33N5O7
|
1
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| 1 |
Ki = 328 nM
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CP0389582
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(S)-5-oxo-4-(2-phenylpyrimidine-4-carboxamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid
Show/Hide
|
C23H27N5O6
|
1
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| 1 |
Ki = 356 nM
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CP0482447
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-(2-ethoxy-2-oxoethoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C26H33N5O9
|
1
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| 1 |
Ki = 372 nM
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CP0534827
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(S)-5-Oxo-5-(4-propionyloxy-piperazin-1-yl)-4-[([1,1';3',1'']terphenyl-5'-carbonyl)-amino]-pentanoic acid
Show/Hide
|
C31H33N3O6
|
1
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| 1 |
Ki = 373 nM
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CP0421653
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(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-[(1,1':3',1''-terphenyl-5'-ylcarbonyl)mino]pentanoic Acid
Show/Hide
|
C31H33N3O6
|
1
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| 1 |
Ki = 373 nM
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CP0473902
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3-(3-(4-(4-acetylpiperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
Show/Hide
|
C18H24N6O4S
|
2
|
| 1 |
Ki = 380 nM
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| 2 |
Ki = 460 nM
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CP0374053
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[4-(6-ethyl-2-piperazin-1-ylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]-(4-phenylphenyl)methanone
Show/Hide
|
C29H32N6OS
|
2
|
| 1 |
Ki = 397 nM
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| 2 |
Ki = 410 nM
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CP0504265
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(S)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(tetrahydro-2H-pyran-4-ylamino)picolinamido)pentanoic acid
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C29H37N5O7
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1
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| 1 |
Ki = 455 nM
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CP0376806
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(3R)-3-hydroxypyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
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C28H36N6O9
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1
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| 1 |
Ki = 459 nM
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CP0508043
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(S)-4-(2,6-diphenylisonicotinamido)-5-oxo-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid
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C30H32N4O6
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1
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| 1 |
Ki = 484 nM
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CP0507710
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(4S)-4-[(2,6-Diphenylisonicotinoyl)amino]-5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid
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C30H32N4O6
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1
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| 1 |
Ki = 484 nM
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CP0514343
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(4S)5-{4-[(2-Methoxyethoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
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C25H30N4O7
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1
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| 1 |
Ki = 492 nM
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CP0534171
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(methylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
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C30H39N7O9
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1
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| 1 |
Ki = 536 nM
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CP0463925
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3-(3-(6-ethyl-4-(4-(2-phenoxyacetyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid
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C24H28N6O5S
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2
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| 1 |
Ki = 539 nM
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| 2 |
Ki = 593 nM
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CP0482446
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(4S)-4-[[5-(2-cyclobutyl-2-oxoethoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C28H35N5O8
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1
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| 1 |
Ki = 574 nM
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CP0499359
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(4S)5-{4-[(Butylamino)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
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C30H41N5O5
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1
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| 1 |
Ki = 613 nM
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CP0513080
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(4S)-4-[[5-[2-[3-(cyclobutylcarbamoyl)azetidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C32H41N7O9
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1
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| 1 |
Ki = 613 nM
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CP0485324
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1-(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)-2-phenylethanone
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C20H22N4OS
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1
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| 1 |
Ki = 660 nM
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CP0534828
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4-(2-(4,6-diphenylpicolinamido)acetyl)piperazin-1-yl propionate
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C27H28N4O4
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1
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| 1 |
Ki = 733 nM
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CP0514344
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ethyl 4-[2-[(4,6-diphenylpyridine-2-carbonyl)amino]acetyl]piperazine-1-carboxylate
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C27H28N4O4
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1
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| 1 |
Ki = 733 nM
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CP0447581
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1-(4-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)piperazin-1-yl)-2,2,2-trifluoroethanone
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C31H31F3N6O2S
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2
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| 1 |
Ki = 839 nM
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| 2 |
Ki = 1810 nM
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CP0447513
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(4S)5-[4-(Anilinocarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
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C32H37N5O5
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1
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| 1 |
Ki = 842 nM
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CP0526317
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-[4-(phenylsulfonyl)piperazin-1-yl]pentanoic acid
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C31H36N4O6S
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1
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| 1 |
Ki = 842 nM
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CP0534170
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(4S)-4-[[5-[2-[(2R)-2-(cyclopropylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C32H41N7O9
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1
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| 1 |
Ki = 958 nM
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CP0534829
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(S)-5-oxo-4-(4-phenylpyrimidine-2-carboxamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid
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C23H27N5O6
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1
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| 1 |
Ki = 1190 nM
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CP0513938
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(S)Ethyl 4-{4-Carboxy-2-[(4-phenylpyrimidine-2-carbonyl)amino]butyryl}piperazine-1-carboxylate
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C23H27N5O6
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1
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| 1 |
Ki = 1190 nM
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CP0506338
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(4S)4-[(1,1'-Biphenyl-3-ylcarbonyl)mino]-5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentanoic Acid
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C29H31N3O4
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1
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| 1 |
Ki = 1310 nM
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CP0506339
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(4S)5-[4-(3-Methylphenyl)piperazin-1-yl]-5-oxo-4-[(1,1':3',1''-terphenyl-5'-ylcarbonyl)amino]pentanoic Acid
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C35H35N3O4
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1
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| 1 |
Ki = 1430 nM
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CP0536487
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(4S)5-Oxo-5-(4-pentanoylpiperazin-1-yl)4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
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C30H40N4O5
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1
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| 1 |
Ki = 1430 nM
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CP0439259
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4-(2-(6-phenylpicolinamido)acetyl)piperazin-1-yl propionate
Show/Hide
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C21H24N4O4
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1
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| 1 |
Ki = 1610 nM
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CP0507711
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ethyl 4-[2-[(6-phenylpyridine-2-carbonyl)amino]acetyl]piperazine-1-carboxylate
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C21H24N4O4
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1
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| 1 |
Ki = 1610 nM
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CP0541367
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(4S)5-(4-Benzoylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C32H36N4O5
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1
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| 1 |
Ki = 1880 nM
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CP0494312
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1-(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)-3-methylbutan-1-one
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C17H24N4OS
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1
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| 1 |
Ki = 2100 nM
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CP0508044
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(4S)5-[4-(Methoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C23H26N4O6
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1
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| 1 |
Ki = 2440 nM
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CP0452750
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(4S)-4-[[5-(2-amino-2-oxoethoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C24H30N6O8
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1
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| 1 |
Ki = 2720 nM
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CP0447586
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1-(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)-3,3,3-trifluoropropan-1-one
Show/Hide
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C15H17F3N4OS
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1
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| 1 |
Ki = 2990 nM
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CP0502645
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(4S)5-(4-Butyrylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C29H38N4O5
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1
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| 1 |
Ki = 3100 nM
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CP0534830
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(S)-4-biphenyl-3-ylcarboxamido-5-oxo-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid
Show/Hide
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C25H29N3O6
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1
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| 1 |
Ki = 3640 nM
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CP0383999
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(4S)4-[(1,10-Biphenyl-3-ylcarbonyl)mino]-5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid
Show/Hide
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C25H29N3O6
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1
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| 1 |
Ki = 3640 nM
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CP0188030
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(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)(phenyl)methanone
Show/Hide
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C19H20N4OS
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1
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| 1 |
Ki = 4400 nM
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CP0537812
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(4S)5-(4-Hexylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C31H44N4O4
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1
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| 1 |
Ki > 2710 nM
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CP0383773
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(4S)5-(4-Isobutyrylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C29H38N4O5
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1
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| 1 |
Ki > 3590 nM
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CP0469879
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-(4-propionylpiperazin-1-yl)pentanoic acid
Show/Hide
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C28H36N4O5
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1
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| 1 |
Ki > 3590 nM
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CP0501498
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(4S)5-[4-(Butylsulfonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C29H40N4O6S
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1
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| 1 |
Ki > 3590 nM
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CP0518792
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(4S)5-[4-(N,N-Dimethylglycyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C29H39N5O5
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1
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| 1 |
Ki > 3590 nM
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CP0518793
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-[4-(propylsulfonyl)piperazin-1-yl]pentanoic acid
Show/Hide
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C28H38N4O6S
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1
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| 1 |
Ki > 3590 nM
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CP0527153
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(4S)5-[4-(Ethylsulfonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C27H36N4O6S
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1
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| 1 |
Ki > 3590 nM
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CP0537763
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(4S)5-Oxo-5-(4-pentylpiperazin-1-yl)4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C30H42N4O4
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1
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| 1 |
Ki > 3590 nM
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CP0537764
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(4S)5-(4-Acetylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C27H34N4O5
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1
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| 1 |
Ki > 3590 nM
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CP0537765
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(4S)5-[4-(Methoxyacetyl)iperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C28H36N4O6
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1
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| 1 |
Ki > 3590 nM
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CP0537766
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(4S)5-Oxo-5-[4-(pentylsulfonyl)piperazin-1-yl]-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C30H42N4O6S
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1
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| 1 |
Ki > 3590 nM
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CP0469880
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(4S)5-(4-Isobutylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
Show/Hide
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C29H40N4O4
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1
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| 1 |
Ki > 3800 nM
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CP0502646
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-(4-propylpiperazin-1-yl)pentanoic acid
Show/Hide
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C28H38N4O4
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1
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| 1 |
Ki > 3800 nM
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CP0381620
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(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(3-oxo-2-phenyl-1H-pyrazole-5-carbonyl)amino]pentanoic acid
Show/Hide
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C22H27N5O7
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1
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| 1 |
Ki > 5000 nM
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CP0452749
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(4S)-4-[[5-[2-(diethylamino)-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
Show/Hide
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C28H38N6O8
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1
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| 1 |
Ki > 5000 nM
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CP0480983
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(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(1-ethoxycarbonylpiperidin-4-yl)amino]-5-oxopentanoic acid
Show/Hide
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C34H45N7O9
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1
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| 1 |
Ki > 5000 nM
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CP0504755
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(S)-5-oxo-4-(picolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid
Show/Hide
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C18H24N4O6
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1
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| 1 |
Ki > 5400 nM
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CP0473493
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(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-[(pyridin-2-ylcarbonyl)mino]pentanoic Acid
Show/Hide
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C18H24N4O6
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1
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| 1 |
Ki > 5400 nM
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CP0518794
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(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-piperazin-1-ylpentanoate
Show/Hide
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C25H32N4O4
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1
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| 1 |
Ki > 5680 nM
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CP0389583
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(S)-5-oxo-4-(4-phenylpicolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid
Show/Hide
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C24H28N4O6
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1
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| 1 |
Ki > 5700 nM
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CP0517542
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(4S)5-[4-(3-Methylphenyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoicAcid
Show/Hide
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C28H30N4O4
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1
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| 1 |
Ki > 5700 nM
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CP0491180
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(4S)5-[4-(3-Methylphenyl)piperazin-1-yl]-5-oxo-4-{[(4-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C28H30N4O4
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1
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| 1 |
Ki > 5700 nM
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CP0497019
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(42S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(4-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
Show/Hide
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C24H28N4O6
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1
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| 1 |
Ki > 5700 nM
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