General Information of the Compound
Compound ID
CP0505736
Compound Name
(4S)4-[({4-[4-(Aminomethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoic Acid
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Structure
Formula
C34H48N6O6
Molecular Weight
636.794
Canonical SMILES
CCCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CCC(CN)CC1
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InChI
InChI=1S/C34H48N6O6/c1-2-3-4-8-21-46-34(45)40-19-17-39(18-20-40)33(44)28(11-12-31(41)42)37-32(43)30-23-27(38-15-13-25(24-35)14-16-38)22-29(36-30)26-9-6-5-7-10-26/h5-7,9-10,22-23,25,28H,2-4,8,11-21,24,35H2,1H3,(H,37,43)(H,41,42)/t28-/m0/s1
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InChIKey
BMTMPFRLYSCFFW-NDEPHWFRSA-N
Physicochemical Property
logP
3.748
Rotatable Bonds
14
Heavy Atom Count
46
Polar Areas
158.4
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
8
Complexity
46

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45271155
ChEMBL ID
CHEMBL556330
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 18 nM
   TI
   LI
   LO
   TS