Protein Information

General Information of the Protein

Protein ID	PT02449
Protein Name	P2Y purinoceptor 12
Secondarily Protein Name	ADP-glucose receptor P2T(AC) P2Y(AC) P2Y(cyc) P2Y12 platelet ADP receptor SP1999
Gene Name	P2RY12
Secondarily Gene Name	HORK3
Sequence	MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor > Family A G protein-coupled receptor > Small molecule receptor (family A GPCR) > Nucleotide-like receptor (family A GPCR) > Purine receptor
Function	Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. Show/Hide
Uniprot ID	Primary ID: Q9H244 Secondarily ID: D3DNJ5 Q546J7 Show/Hide
Ensembl ID	ENSG00000169313
HGNC ID	HGNC:18124
Subcellular Location	Cell membrane

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000011 , CHO

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0540048 Compound Info	2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5-methylindol-1-yl]acetic acid Show/Hide	C26H26N4O4	1
1	IC50 = 0.9 nM Bioactivity Info	TI LI LO TS
CP0475952 Compound Info	(4S)-5-(4-butoxycarbonylpiperazin-1-yl)-4-[[6-[(3S)-3-methoxypyrrolidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C30H40N6O7	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0426660 Compound Info	2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5,6-dimethylindol-1-yl]acetic acid Show/Hide	C27H28N4O4	1
1	IC50 = 5.1 nM Bioactivity Info	TI LI LO TS
CP0100779 Compound Info	ethyl 5-cyano-2-methyl-6-[3-[(4-methylphenyl)methylsulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate Show/Hide	C22H24N4O5S	2
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0054221 Compound Info	ethyl 5-cyano-2-methyl-6-[4-[(4-methylphenyl)methylsulfonylcarbamoyl]piperidin-1-yl]pyridine-3-carboxylate Show/Hide	C24H28N4O5S	2
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0540047 Compound Info	3-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5-methylindol-1-yl]propanoic acid Show/Hide	C27H28N4O4	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0556592 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)piperidin-1-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C29H38ClN7O3	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0475927 Compound Info	(4S)-5-(4-butoxycarbonylpiperazin-1-yl)-4-[[6-[(1S,2R)-2-(methoxymethyl)cyclopropyl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C30H39N5O7	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0295715 Compound Info	ethyl 6-[3-[(4-chlorophenyl)methylsulfonylcarbamoyl]azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate Show/Hide	C21H21ClN4O5S	2
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
2	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0116124 Compound Info	ethyl 6-[4-(benzylsulfonylcarbamoyl)piperidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate Show/Hide	C23H26N4O5S	2
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
2	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0120516 Compound Info	ethyl 5-cyano-6-[4-[(2,4-difluorophenyl)methylsulfonylcarbamoyl]piperidin-1-yl]-2-methylpyridine-3-carboxylate Show/Hide	C23H24F2N4O5S	2
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
2	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0424536 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(2-phenyl-6-thiophen-3-ylpyrimidine-4-carbonyl)amino]pentanoic acid Show/Hide	C27H29N5O6S	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0424283 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H35ClN6O4	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0426668 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-[4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl]-2-oxoethyl]indole-3-carboxamide Show/Hide	C34H36ClN7O4	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0556591 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-[4-[2-(dimethylamino)-2-oxoethyl]piperazin-1-yl]-2-oxoethyl]indole-3-carboxamide Show/Hide	C33H38ClN7O4	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0072394 Compound Info	ethyl 5-cyano-6-[3-[(4-fluorophenyl)methylsulfonylcarbamoyl]azetidin-1-yl]-2-methylpyridine-3-carboxylate Show/Hide	C21H21FN4O5S	2
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0540053 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C37H39FN6O3	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0042856 Compound Info	ethyl 5-cyano-6-[4-[(4-fluorophenyl)methylsulfonylcarbamoyl]piperidin-1-yl]-2-methylpyridine-3-carboxylate Show/Hide	C23H25FN4O5S	2
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
2	IC50 = 38 nM Bioactivity Info	TI LI LO TS
CP0540051 Compound Info	1-[2-[(3S,7R,8aS)-7-hydroxy-3-methyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide Show/Hide	C34H40N6O4	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0555065 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-[4-(2-methoxyethyl)piperazin-1-yl]-2-oxoethyl]indole-3-carboxamide Show/Hide	C32H37ClN6O4	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0550793 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(3S)-3-methoxypyrrolidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C28H36N6O7	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0154221 Compound Info	ethyl 6-[3-(benzylsulfonylcarbamoyl)azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate Show/Hide	C21H22N4O5S	2
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
2	IC50 = 33 nM Bioactivity Info	TI LI LO TS
CP0483743 Compound Info	4-[2-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoylamino]-4-methylphenoxy]butanoic acid Show/Hide	C26H30N4O5	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0540055 Compound Info	N-[6-(4-butanoyl-5-methylpyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C28H31ClN8O3	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0400243 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2-fluoroethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C32H37FN6O3	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0568960 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2,2-difluoroethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C32H36F2N6O3	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0375260 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2-methoxyethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C33H40N6O4	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0490034 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(1-hydroxy-2-methylpropan-2-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C27H35N5O7	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0550792 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(3-hydroxypiperidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C28H36N6O7	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0375262 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methoxy-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H36N6O4	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0428173 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(1S,2S)-2-(hydroxymethyl)cyclopropyl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C27H33N5O7	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0553469 Compound Info	4-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5-methylindol-1-yl]butanoic acid Show/Hide	C28H30N4O4	1
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0508101 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[6-[[(3R)-oxolan-3-yl]amino]-2-phenylpyrimidine-4-carbonyl]amino]pentanoic acid Show/Hide	C27H34N6O7	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0509070 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-(2-oxo-2-piperazin-1-ylethyl)indole-3-carboxamide Show/Hide	C30H34N6O3	1
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
CP0398866 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(4-methylpyrazol-1-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C27H31N7O6	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0533178 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(3,4-dimethylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0555062 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C30H33ClN6O3	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0553473 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-(3,4,5-trimethylpiperazin-1-yl)ethyl]indole-3-carboxamide Show/Hide	C33H40N6O3	1
1	IC50 = 28 nM Bioactivity Info	TI LI LO TS
CP0568959 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(cyclopropylmethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C34H40N6O3	1
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0154222 Compound Info	ethyl 5-cyano-6-[4-[(4-methoxyphenyl)methylsulfonylcarbamoyl]piperidin-1-yl]-2-methylpyridine-3-carboxylate Show/Hide	C24H28N4O6S	2
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
2	IC50 = 58 nM Bioactivity Info	TI LI LO TS
CP0481999 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(4-methoxyphenyl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C30H33N5O7	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0509063 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(dimethylamino)-2-oxoethyl]-5,6-dimethylindole-3-carboxamide Show/Hide	C29H33N5O3	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0556584 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide;hydrochloride Show/Hide	C31H37ClN6O3	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0395740 Compound Info	ethyl 5-cyano-2-methyl-6-[3-[(3-methylphenyl)methylsulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate Show/Hide	C22H24N4O5S	2
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
2	IC50 = 65 nM Bioactivity Info	TI LI LO TS
CP0568957 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C33H38N6O3	1
1	IC50 = 33 nM Bioactivity Info	TI LI LO TS
CP0381449 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-6-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H35ClN6O3	1
1	IC50 = 34 nM Bioactivity Info	TI LI LO TS
CP0480710 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(2-hydroxypropan-2-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C26H33N5O7	1
1	IC50 = 35 nM Bioactivity Info	TI LI LO TS
CP0456328 Compound Info	(4S)-4-[(6-tert-butyl-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C27H35N5O6	1
1	IC50 = 36 nM Bioactivity Info	TI LI LO TS
CP0433090 Compound Info	ethyl 6-[4-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]piperidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate Show/Hide	C20H21ClN4O5S2	2
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
2	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0555061 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5,6-dimethyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide;hydrochloride Show/Hide	C32H38N6O3	1
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0448284 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(4-hydroxycyclohexyl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C29H37N5O7	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0509076 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)cyclohexyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C30H39ClN6O3	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0400242 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C32H38N6O4	1
1	IC50 = 41 nM Bioactivity Info	TI LI LO TS
CP0448285 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(1R,2R)-2-(methoxymethyl)cyclopropyl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C28H35N5O7	1
1	IC50 = 43 nM Bioactivity Info	TI LI LO TS
CP0410575 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(4-cyclopropylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C33H38N6O3	1
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0419622 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(3S)-3-hydroxypyrrolidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C27H34N6O7	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0524150 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(4-methylpiperazin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C28H37N7O6	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0375258 Compound Info	1-[2-(3-aminopiperidin-1-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide Show/Hide	C31H36N6O3	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0509069 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(3-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H36N6O3	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0410574 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[methyl-(1-methylpyrrolidin-3-yl)amino]-2-oxoethyl]indole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0555060 Compound Info	4-[1-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-6-methylindol-3-yl]butanoic acid Show/Hide	C28H30N4O4	1
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0375265 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)-2-cyanophenyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H32ClN7O3	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0424282 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-6-fluoro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C30H32ClFN6O3	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0555063 Compound Info	5-bromo-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-6-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H35BrN6O3	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0509074 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-5-(trifluoromethyl)indole-3-carboxamide Show/Hide	C31H33F3N6O3	1
1	IC50 = 50 nM Bioactivity Info	TI LI LO TS
CP0452827 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-[(3R)-3-hydroxypyrrolidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C27H34N6O7	1
1	IC50 = 52 nM Bioactivity Info	TI LI LO TS
CP0481930 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(2-phenyl-6-propan-2-ylpyrimidine-4-carbonyl)amino]pentanoic acid Show/Hide	C26H33N5O6	1
1	IC50 = 52 nM Bioactivity Info	TI LI LO TS
CP0459748 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(2-phenyl-6-pyridin-4-ylpyrimidine-4-carbonyl)amino]pentanoic acid Show/Hide	C28H30N6O6	1
1	IC50 = 53 nM Bioactivity Info	TI LI LO TS
CP0459749 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(1-hydroxypropan-2-ylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C26H34N6O7	1
1	IC50 = 56 nM Bioactivity Info	TI LI LO TS
CP0140475 Compound Info	ethyl 6-[3-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate Show/Hide	C18H17ClN4O5S2	2
1	IC50 = 59 nM Bioactivity Info	TI LI LO TS
2	IC50 = 99 nM Bioactivity Info	TI LI LO TS
CP0456327 Compound Info	(4S)-4-[(6-cyclopropyl-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C26H31N5O6	1
1	IC50 = 59.5 nM Bioactivity Info	TI LI LO TS
CP0893864 Compound Info	Sodium 1-Amino-4-(4-hydroxy-3-methylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate Show/Hide	C21H15N2NaO6S	1
1	IC50 = 60.4 nM Bioactivity Info	TI LI LO TS
CP0509064 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-[[(3S)-pyrrolidin-3-yl]amino]ethyl]indole-3-carboxamide Show/Hide	C30H34N6O3	1
1	IC50 = 61 nM Bioactivity Info	TI LI LO TS
CP0556587 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(2-imidazol-1-ylethylamino)-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C31H33N7O3	1
1	IC50 = 61 nM Bioactivity Info	TI LI LO TS
CP0383997 Compound Info	(S)Ethyl 4-{4-Carboxy-2-[(2-phenylpyrimidine-4-carbonyl)amino]butyryl}piperazine-1-carboxylate Show/Hide	C29H31N5O6	2
1	IC50 = 64 nM Bioactivity Info	TI LI LO TS
2	Ki = 356 nM Bioactivity Info	TI LI LO TS
CP0483746 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[3-(methylamino)piperidin-1-yl]-2-oxoethyl]indole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 65 nM Bioactivity Info	TI LI LO TS
CP0509072 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]indole-3-carboxamide Show/Hide	C32H35F3N6O3	1
1	IC50 = 66 nM Bioactivity Info	TI LI LO TS
CP0553472 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(4-ethylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 66 nM Bioactivity Info	TI LI LO TS
CP0461893 Compound Info	ethyl 5-cyano-2-methyl-6-[3-[(2-methylphenyl)methylsulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate Show/Hide	C22H24N4O5S	2
1	IC50 = 67 nM Bioactivity Info	TI LI LO TS
2	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0533179 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-oxoethyl]indole-3-carboxamide Show/Hide	C32H36N6O3	1
1	IC50 = 70 nM Bioactivity Info	TI LI LO TS
CP0375256 Compound Info	1-[2-(4-aminopiperidin-1-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide Show/Hide	C31H36N6O3	1
1	IC50 = 71 nM Bioactivity Info	TI LI LO TS
CP0533175 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[(1-methylpiperidin-3-yl)amino]-2-oxoethyl]indole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 71 nM Bioactivity Info	TI LI LO TS
CP0424542 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[2-phenyl-6-(1H-pyrazol-4-yl)pyrimidine-4-carbonyl]amino]pentanoic acid Show/Hide	C26H29N7O6	1
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
CP0375259 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[3-(dimethylamino)piperidin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C33H40N6O3	1
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
CP0540056 Compound Info	5-(4-butanoyl-5-methylpyrazol-1-yl)-2-[[5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carbonyl]amino]benzoic acid Show/Hide	C31H33ClN6O5	1
1	IC50 = 75 nM Bioactivity Info	TI LI LO TS
CP0459750 Compound Info	(4S)-4-[[6-(3-aminopyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C27H35N7O6	1
1	IC50 = 76 nM Bioactivity Info	TI LI LO TS
CP0410532 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-cyano-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H33N7O3	1
1	IC50 = 76 nM Bioactivity Info	TI LI LO TS
CP0509067 Compound Info	1-[2-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide Show/Hide	C33H38N6O3	1
1	IC50 = 76 nM Bioactivity Info	TI LI LO TS
CP0555059 Compound Info	4-[2-[[4-(4-ethoxycarbonyl-3,5-dimethylpyrazol-1-yl)phenyl]carbamoylamino]phenoxy]butanoic acid Show/Hide	C25H28N4O6	1
1	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0509068 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-(4-propan-2-ylpiperazin-1-yl)ethyl]indole-3-carboxamide Show/Hide	C33H40N6O3	1
1	IC50 = 82 nM Bioactivity Info	TI LI LO TS
CP0410514 Compound Info	2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-2,5-dimethylindol-1-yl]acetic acid Show/Hide	C27H28N4O4	1
1	IC50 = 84 nM Bioactivity Info	TI LI LO TS
CP0533176 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[methyl-[(1-methylpiperidin-3-yl)methyl]amino]-2-oxoethyl]indole-3-carboxamide Show/Hide	C34H42N6O3	1
1	IC50 = 84 nM Bioactivity Info	TI LI LO TS
CP0540052 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[(1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C31H34N6O3	1
1	IC50 = 86 nM Bioactivity Info	TI LI LO TS
CP0509066 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[3-(dimethylamino)pyrrolidin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 87 nM Bioactivity Info	TI LI LO TS
CP0426661 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[1-(dimethylamino)propan-2-ylamino]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C31H38N6O3	1
1	IC50 = 88 nM Bioactivity Info	TI LI LO TS
CP0510436 Compound Info	ethyl 5-cyano-6-[3-(cyclohexylmethylsulfonylcarbamoyl)azetidin-1-yl]-2-methylpyridine-3-carboxylate Show/Hide	C21H28N4O5S	2
1	IC50 = 89 nM Bioactivity Info	TI LI LO TS
2	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0556590 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C33H38N6O3	1
1	IC50 = 89 nM Bioactivity Info	TI LI LO TS
CP0483745 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[2-(dimethylamino)ethylamino]-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C30H36N6O3	1
1	IC50 = 92 nM Bioactivity Info	TI LI LO TS
CP0375254 Compound Info	methyl 2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-5-methylindol-1-yl]acetate Show/Hide	C27H28N4O4	1
1	IC50 = 93 nM Bioactivity Info	TI LI LO TS
CP0483744 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[methyl-[2-(methylamino)ethyl]amino]-2-oxoethyl]indole-3-carboxamide Show/Hide	C30H36N6O3	1
1	IC50 = 94 nM Bioactivity Info	TI LI LO TS
CP0509065 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[3-(methylamino)pyrrolidin-1-yl]-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H36N6O3	1
1	IC50 = 94 nM Bioactivity Info	TI LI LO TS
CP0556589 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(4-methyl-1,4-diazepan-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 95 nM Bioactivity Info	TI LI LO TS
CP0396884 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[2-phenyl-6-(propan-2-ylamino)pyrimidine-4-carbonyl]amino]pentanoic acid Show/Hide	C26H34N6O6	1
1	IC50 = 95.5 nM Bioactivity Info	TI LI LO TS
CP0490035 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(1-methoxypropan-2-ylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C27H36N6O7	1
1	IC50 = 97 nM Bioactivity Info	TI LI LO TS
CP0452823 Compound Info	(4S)-4-[(6-butyl-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C27H35N5O6	1
1	IC50 = 98 nM Bioactivity Info	TI LI LO TS
CP0555064 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5,6-dichloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C30H32Cl2N6O3	1
1	IC50 = 99 nM Bioactivity Info	TI LI LO TS
CP0424540 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[(6-morpholin-4-yl-2-phenylpyrimidine-4-carbonyl)amino]-5-oxopentanoic acid Show/Hide	C27H34N6O7	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0540050 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-[2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]indole-3-carboxamide Show/Hide	C36H44N6O3	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0381445 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(3,5-dimethylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 102 nM Bioactivity Info	TI LI LO TS
CP0533177 Compound Info	1-[2-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide Show/Hide	C32H36N6O3	1
1	IC50 = 106 nM Bioactivity Info	TI LI LO TS
CP0375266 Compound Info	ethyl 5-cyano-2-methyl-6-[3-[[3-(trifluoromethyl)phenyl]methylsulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate Show/Hide	C22H21F3N4O5S	2
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
2	IC50 = 290 nM Bioactivity Info	TI LI LO TS
CP0553470 Compound Info	1-[2-[2-(aminomethyl)piperidin-1-yl]-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 111 nM Bioactivity Info	TI LI LO TS
CP0375257 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[4-(methylamino)piperidin-1-yl]-2-oxoethyl]indole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 115 nM Bioactivity Info	TI LI LO TS
CP0553471 Compound Info	1-[2-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[2,3-c]pyrrol-5-yl)-2-oxoethyl]-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methylindole-3-carboxamide Show/Hide	C32H36N6O3	1
1	IC50 = 117 nM Bioactivity Info	TI LI LO TS
CP0568961 Compound Info	6-bromo-N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H35BrN6O3	1
1	IC50 = 118 nM Bioactivity Info	TI LI LO TS
CP0403953 Compound Info	ethyl 6-[4-(benzenesulfonylcarbamoyl)piperidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate Show/Hide	C22H24N4O5S	2
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
2	IC50 = 710 nM Bioactivity Info	TI LI LO TS
CP0568958 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-(4-butylpiperazin-1-yl)-2-oxoethyl]-5-methylindole-3-carboxamide Show/Hide	C34H42N6O3	1
1	IC50 = 121 nM Bioactivity Info	TI LI LO TS
CP0456329 Compound Info	(4S)-4-[[6-(benzylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C30H34N6O6	1
1	IC50 = 122 nM Bioactivity Info	TI LI LO TS
CP0556586 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[methyl(2-pyrrolidin-1-ylethyl)amino]-2-oxoethyl]indole-3-carboxamide Show/Hide	C33H40N6O3	1
1	IC50 = 124 nM Bioactivity Info	TI LI LO TS
CP0452824 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(1-oxidopyridin-1-ium-3-yl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C28H30N6O7	1
1	IC50 = 129 nM Bioactivity Info	TI LI LO TS
CP0510435 Compound Info	ethyl 5-chloro-6-[4-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]piperidin-1-yl]pyridine-3-carboxylate Show/Hide	C18H19Cl2N3O5S2	2
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
2	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0509075 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-6-chloro-5-methyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H35ClN6O3	1
1	IC50 = 138 nM Bioactivity Info	TI LI LO TS
CP0556588 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-[(1-methylpiperidin-4-yl)amino]-2-oxoethyl]indole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 139 nM Bioactivity Info	TI LI LO TS
CP0452826 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(ethylsulfonylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C25H32N6O8S	1
1	IC50 = 142 nM Bioactivity Info	TI LI LO TS
CP0553474 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-fluoro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C30H33FN6O3	1
1	IC50 = 142 nM Bioactivity Info	TI LI LO TS
CP0566986 Compound Info	N-[4-(4-acetyl-5-methylpyrazol-1-yl)phenyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C28H29ClN6O3	1
1	IC50 = 143 nM Bioactivity Info	TI LI LO TS
CP0072393 Compound Info	ethyl 5-cyano-2-methyl-6-[4-[(4-propan-2-ylphenyl)methylsulfonylcarbamoyl]piperidin-1-yl]pyridine-3-carboxylate Show/Hide	C26H32N4O5S	2
1	IC50 = 160 nM Bioactivity Info	TI LI LO TS
2	IC50 = 250 nM Bioactivity Info	TI LI LO TS
CP0410390 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[2-phenyl-6-(propylamino)pyrimidine-4-carbonyl]amino]pentanoic acid Show/Hide	C26H34N6O6	1
1	IC50 = 162 nM Bioactivity Info	TI LI LO TS
CP0410391 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(2-hydroxyethylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C25H32N6O7	1
1	IC50 = 169 nM Bioactivity Info	TI LI LO TS
CP0429090 Compound Info	(4S)-4-[(6-anilino-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C29H32N6O6	1
1	IC50 = 177 nM Bioactivity Info	TI LI LO TS
CP0452825 Compound Info	(4S)-4-[(6-benzamido-2-phenylpyrimidine-4-carbonyl)amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C30H32N6O7	1
1	IC50 = 178 nM Bioactivity Info	TI LI LO TS
CP0375255 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-5-methyl-1-[2-oxo-2-(2-pyrrolidin-1-ylethylamino)ethyl]indole-3-carboxamide Show/Hide	C32H38N6O3	1
1	IC50 = 194 nM Bioactivity Info	TI LI LO TS
CP0523037 Compound Info	(4S)-4-[[6-(2-carboxyethylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C26H32N6O8	1
1	IC50 = 198 nM Bioactivity Info	TI LI LO TS
CP0432333 Compound Info	ethyl 6-[3-(benzenesulfonylcarbamoyl)azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate Show/Hide	C20H20N4O5S	2
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
2	IC50 = 840 nM Bioactivity Info	TI LI LO TS
CP0481928 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(2-phenyl-6-piperidin-1-ylpyrimidine-4-carbonyl)amino]pentanoic acid Show/Hide	C28H36N6O6	1
1	IC50 = 201 nM Bioactivity Info	TI LI LO TS
CP0537536 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(3-hydroxypropyl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C26H33N5O7	1
1	IC50 = 218 nM Bioactivity Info	TI LI LO TS
CP0481850 Compound Info	(4S)-4-[[6-(cyclohexanecarbonylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C30H38N6O7	1
1	IC50 = 219 nM Bioactivity Info	TI LI LO TS
CP0465458 Compound Info	ethyl 5-cyano-2-methyl-6-[3-(2-phenylethylsulfonylcarbamoyl)azetidin-1-yl]pyridine-3-carboxylate Show/Hide	C22H24N4O5S	1
1	IC50 = 220 nM Bioactivity Info	TI LI LO TS
CP0396883 Compound Info	CHEMBL3322636 Show/Hide	C29H38N6O7	1
1	IC50 = 223 nM Bioactivity Info	TI LI LO TS
CP0432332 Compound Info	ethyl 5-cyano-6-[3-[[4-(hydroxymethyl)phenyl]methylsulfonylcarbamoyl]azetidin-1-yl]-2-methylpyridine-3-carboxylate Show/Hide	C22H24N4O6S	2
1	IC50 = 230 nM Bioactivity Info	TI LI LO TS
2	IC50 = 730 nM Bioactivity Info	TI LI LO TS
CP0452822 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(2-morpholin-4-ylethylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C29H39N7O7	1
1	IC50 = 257 nM Bioactivity Info	TI LI LO TS
CP0428172 Compound Info	(4S)-4-[[6-(benzenesulfonamido)-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C29H32N6O8S	1
1	IC50 = 266 nM Bioactivity Info	TI LI LO TS
CP0568962 Compound Info	N-[4-(4-butanoyl-5-methylpyrazol-1-yl)-2-carbamoylphenyl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C31H34ClN7O4	1
1	IC50 = 266 nM Bioactivity Info	TI LI LO TS
CP0540049 Compound Info	2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]carbamoyl]-4,5-dimethylindol-1-yl]acetic acid Show/Hide	C27H28N4O4	1
1	IC50 = 272 nM Bioactivity Info	TI LI LO TS
CP0375264 Compound Info	N-[5-(4-butanoyl-5-methylpyrazol-1-yl)pyrazin-2-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C28H31ClN8O3	1
1	IC50 = 275 nM Bioactivity Info	TI LI LO TS
CP0508198 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(3-hydroxypropylamino)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C26H34N6O7	1
1	IC50 = 279 nM Bioactivity Info	TI LI LO TS
CP0475951 Compound Info	(4S)-4-[[6-[2-[(dimethylamino)methyl]piperidin-1-yl]-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C31H43N7O6	1
1	IC50 = 291 nM Bioactivity Info	TI LI LO TS
CP0509062 Compound Info	2-[3-[[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-methylcarbamoyl]-5-methylindol-1-yl]acetic acid Show/Hide	C27H28N4O4	1
1	IC50 = 304 nM Bioactivity Info	TI LI LO TS
CP0432334 Compound Info	ethyl 5-chloro-6-[3-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]azetidin-1-yl]pyridine-3-carboxylate Show/Hide	C16H15Cl2N3O5S2	2
1	IC50 = 310 nM Bioactivity Info	TI LI LO TS
2	IC50 = 500 nM Bioactivity Info	TI LI LO TS
CP0540054 Compound Info	5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-N-[4-(5-methyl-4-propanoylpyrazol-1-yl)phenyl]indole-3-carboxamide Show/Hide	C29H31ClN6O3	1
1	IC50 = 336 nM Bioactivity Info	TI LI LO TS
CP0424543 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[6-(morpholin-4-ylmethyl)-2-phenylpyrimidine-4-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C28H36N6O7	1
1	IC50 = 428 nM Bioactivity Info	TI LI LO TS
CP0553475 Compound Info	[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl] 5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxylate Show/Hide	C30H32ClN5O4	1
1	IC50 = 480 nM Bioactivity Info	TI LI LO TS
CP0463439 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[2-phenyl-6-(piperidin-1-ylmethyl)pyrimidine-4-carbonyl]amino]pentanoic acid Show/Hide	C29H38N6O6	1
1	IC50 = 533 nM Bioactivity Info	TI LI LO TS
CP0566987 Compound Info	1-[1-[4-[5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carbonyl]-2,3-dihydro-1,4-benzoxazin-7-yl]-5-methylpyrazol-4-yl]butan-1-one Show/Hide	C32H35ClN6O4	1
1	IC50 = 559 nM Bioactivity Info	TI LI LO TS
CP0375263 Compound Info	5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-N-[4-[5-methyl-4-(4,4,4-trifluorobutanoyl)pyrazol-1-yl]phenyl]indole-3-carboxamide Show/Hide	C30H30ClF3N6O3	1
1	IC50 = 574 nM Bioactivity Info	TI LI LO TS
CP0509061 Compound Info	ethyl 1-[4-[(4-chlorophenyl)carbamoylamino]phenyl]-3,5-dimethylpyrazole-4-carboxylate Show/Hide	C21H21ClN4O3	1
1	IC50 = 1260 nM Bioactivity Info	TI LI LO TS
CP0509060 Compound Info	ethyl 1-[4-[(2-methoxyphenyl)methylcarbamoyl]phenyl]-3,5-dimethylpyrazole-4-carboxylate Show/Hide	C23H25N3O4	1
1	IC50 = 1540 nM Bioactivity Info	TI LI LO TS
CP0885816 Compound Info	Sodium 1-Amino-4-[4-(3,4-dimethylphenylthio)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate Show/Hide	C28H21N2NaO5S2	1
1	IC50 = 2340 nM Bioactivity Info	TI LI LO TS
CP0894768 Compound Info	Sodium 1-Amino-4-[4-(2,4-dimethylphenylthio)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate Show/Hide	C28H21N2NaO5S2	1
1	IC50 = 2410 nM Bioactivity Info	TI LI LO TS
CP0523057 Compound Info	(4S)-4-[[6-[2-(dimethylamino)ethylamino]-2-phenylpyrimidine-4-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C27H37N7O6	1
1	IC50 = 2780 nM Bioactivity Info	TI LI LO TS
CP0854864 Compound Info	Sodium 1-Amino-4-[4-(2,5-dimethylphenylthio)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate Show/Hide	C28H21N2NaO5S2	1
1	IC50 = 2960 nM Bioactivity Info	TI LI LO TS
CP0652102 Compound Info	sodium 1-amino-9,10-dioxo-4-(phenylamino)-9,10-dihydroanthracene-2-sulfonate Show/Hide	C20H13N2NaO5S	1
1	IC50 = 3120 nM Bioactivity Info	TI LI LO TS
CP0893862 Compound Info	Sodium 1-Amino-4-[4-(3-pyridin-3-ylmethylthio)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate Show/Hide	C26H18N3NaO5S2	1
1	IC50 = 3590 nM Bioactivity Info	TI LI LO TS
CP0032210 Compound Info	4-(4-piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid Show/Hide	C29H24F3NO2	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0851936 Compound Info	sodium 1-amino-9,10-dioxo-4-(4-(phenylamino)-3-sulfonatophenylamino)-9,10-dihydroanthracene-2-sulfonate Show/Hide	C26H17N3Na2O8S2	1
1	Kd = 0.1585 nM Bioactivity Info	TI LI LO TS
CP0087103 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-(ethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C34H46N6O7	2
1	Ki = 0.38 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.68 nM Bioactivity Info	TI LI LO TS
CP0189076 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(4-(pyrrolidin-1-ylmethyl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C36H51N7O6	1
1	Ki = 0.4 nM Bioactivity Info	TI LI LO TS
CP0189074 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C36H49N7O7	1
1	Ki = 0.46 nM Bioactivity Info	TI LI LO TS
CP0498717 Compound Info	(S)-4-(4-(4-(ethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H48N6O7	1
1	Ki = 0.58 nM Bioactivity Info	TI LI LO TS
CP0254408 Compound Info	(S)-4-(6-(4-(ethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H47N7O7	1
1	Ki = 0.6 nM Bioactivity Info	TI LI LO TS
CP0506501 Compound Info	(4S)-4-[(6-{4-[(diethylamino)methyl]piperidin-1-yl}-2-phenylpyrimidin-4-yl)formamido]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C36H53N7O6	1
1	Ki = 0.61 nM Bioactivity Info	TI LI LO TS
CP0532602 Compound Info	(S)-4-(4-(3-carbamoylazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H40N6O7	1
1	Ki = 0.64 nM Bioactivity Info	TI LI LO TS
CP0535227 Compound Info	(S)-4-(6-(4-(2-(ethylamino)-2-oxoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H49N7O7	1
1	Ki = 0.67 nM Bioactivity Info	TI LI LO TS
CP0506503 Compound Info	(S)-4-(6-(4-aminopiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H43N7O6	1
1	Ki = 0.69 nM Bioactivity Info	TI LI LO TS
CP0494757 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C35H47N7O7	1
1	Ki = 0.7 nM Bioactivity Info	TI LI LO TS
CP0089673 Compound Info	(S)-4-(6-(4-(2-hydroxyethoxy)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O8	1
1	Ki = 0.71 nM Bioactivity Info	TI LI LO TS
CP0439242 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-(diethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C35H49N7O7	1
1	Ki = 0.79 nM Bioactivity Info	TI LI LO TS
CP0372050 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(4-(4-((2-oxopyrrolidin-1-yl)methyl)piperidin-1-yl)-6-phenylpicolinamido)pentanoic acid Show/Hide	C36H48N6O7	1
1	Ki = 0.79 nM Bioactivity Info	TI LI LO TS
CP0525484 Compound Info	(4S)-5-(4-butoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C35H47N7O9	1
1	Ki = 0.8 nM Bioactivity Info	TI LI LO TS
CP0439241 Compound Info	(S)-4-(6-(4-(azetidine-1-carbonyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H47N7O7	1
1	Ki = 0.83 nM Bioactivity Info	TI LI LO TS
CP0541510 Compound Info	(S)-4-(6-(4-(2-(methylamino)-2-oxoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H47N7O7	1
1	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
CP0418164 Compound Info	(S)-4-(6-(4-(2-(azetidin-1-yl)-2-oxoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H49N7O7	1
1	Ki = 0.92 nM Bioactivity Info	TI LI LO TS
CP0498715 Compound Info	(S)-4-(4-(4-(dimethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H48N6O7	1
1	Ki = 0.98 nM Bioactivity Info	TI LI LO TS
CP0491253 Compound Info	(S)-5-oxo-4-(6-(4-((2-oxopyrrolidin-1-yl)methyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H49N7O7	1
1	Ki = 0.99 nM Bioactivity Info	TI LI LO TS
CP0529859 Compound Info	(S)-4-(6-morpholino-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C30H40N6O7	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0429734 Compound Info	(4S)-4-[({4-[3-(Dimethylamino)propyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C32H45N5O6	1
1	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0415390 Compound Info	(4S)-5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[4-(pyrrolidin-1-ylmethyl)piperidin-1-yl]pyridin-2-yl}-carbonyl)amino]pentanoic Acid Show/Hide	C37H52N6O6	1
1	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
CP0463982 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C36H50N6O7	1
1	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
CP0189073 Compound Info	(S)-4-(6-(4-((methylamino)methyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H47N7O6	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0473784 Compound Info	(S)-4-(6-(2-methoxyethoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C29H39N5O8	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0488877 Compound Info	(S)-4-(6-(2-methoxyethylamino)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C29H40N6O7	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0494778 Compound Info	(S)-4-(6-(3-ethoxyazetidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H42N6O7	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0506505 Compound Info	(S)-4-(4-(2-methoxyethoxy)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C29H39N5O8	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0535231 Compound Info	(S)-4-(6-(4-carbamoylpiperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H42N8O7	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0502340 Compound Info	(S)-4-(4-(4-(azetidine-1-carbonyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H48N6O7	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0501378 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-morpholinopiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C34H47N7O7	1
1	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0535228 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-(dimethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C33H45N7O7	1
1	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0375636 Compound Info	(4S)4-[({4-[(1-Acetylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C35H47N5O8	1
1	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0381216 Compound Info	(4S)4-{[(4-{[1-(Ethoxycarbonyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C36H49N5O9	1
1	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0500067 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-methoxypiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C31H42N6O7	1
1	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0513905 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-((R)-3-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl)picolinamido)pentanoic acid Show/Hide	C36H48N6O7	1
1	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0375518 Compound Info	(4S)4-{[(4-{[(2-Methoxyethoxy)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C35H49N5O9	1
1	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0513934 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-({[(piperidin-4-ylmethyl)amino]carbonyl}amino)pyridin-2-yl]carbonyl}amino)pentanoic acid Show/Hide	C38H55N7O7	1
1	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0089676 Compound Info	(S)-4-(6-(4-(diethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H51N7O7	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0089677 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(4-(pyrrolidin-1-yl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C35H49N7O6	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0375650 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-[({6-phenyl-4-[4-(pyrrolidin-1-ylmethyl)piperidin-1-yl]pyridin-2-yl}carbonyl)amino]pentanoic Acid Show/Hide	C36H50N6O6	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0502663 Compound Info	(4S)4-{[(4-{4-[(Methylamino)ethyl]piperidin-1-yl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C34H48N6O6	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0518988 Compound Info	(S)-4-(4-(4-((ethylamino)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H50N6O6	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0471476 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-({[4-({[(3R)3-methoxypyrrolidin-1-yl]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-oxopentanoic Acid Show/Hide	C32H41N5O9	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0523991 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-({[methyl-(tetrahydro-2H-pyran-4-ylmethyl)mino]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid Show/Hide	C34H45N5O9	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0507227 Compound Info	butyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-(2H-tetrazol-5-yl)butanoyl]piperazine-1-carboxylate Show/Hide	C35H47N11O7	1
1	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0494691 Compound Info	(S)-5-oxo-4-(6-(4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H51N7O7	1
1	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
CP0384515 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-(4-(pyrrolidin-1-yl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C34H47N7O6	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0421986 Compound Info	(S)-4-(4-(3-(methylcarbamoyl)azetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H42N6O7	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0498701 Compound Info	(S)-4-(4-((S)-3-(diethylcarbamoyl)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H50N6O7	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0510849 Compound Info	(S)-4-(4-(4-(2-amino-2-oxoethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H45N7O7	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0542752 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-((S)-3-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl)picolinamido)pentanoic acid Show/Hide	C36H48N6O7	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0453572 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(morpholin-4-ylcarbonyl)xy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C31H39N5O9	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0502647 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-{[(piperidin-4-ylmethoxy)carbonyl]amino}pyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C38H54N6O8	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0523992 Compound Info	(4S)-4-[({4-[(4-Acetylpiperazin-1-yl)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H44N6O8	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0384277 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-({[4-({[methyl-(tetrahydrofuran-3-yl)mino]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid Show/Hide	C32H41N5O9	1
1	Ki = 1.8 nM Bioactivity Info	TI LI LO TS
CP0498719 Compound Info	(4S)4-{[(4-{4-[(Dimethylamino)ethyl]piperidin-1-yl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C35H50N6O6	1
1	Ki = 1.9 nM Bioactivity Info	TI LI LO TS
CP0518835 Compound Info	(4S)4-{[(4-{[(3-Aminopropoxy)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C35H50N6O8	1
1	Ki = 1.9 nM Bioactivity Info	TI LI LO TS
CP0303192 Compound Info	(S)-4-(6-(4-carbamoylpiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N7O7	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0491246 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(piperazin-1-yl)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C30H41N7O6	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0534318 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(4-(2-methoxyethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C33H46N6O7	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0401970 Compound Info	(S)-4-(4-(3-methoxyazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H41N5O7	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0533226 Compound Info	(S)-4-(4-(3-(ethylcarbamoyl)azetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H44N6O7	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0429735 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[(dimethylamino)carbonyl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C29H37N5O8	1
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0491244 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C37H53N7O6	1
1	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0494774 Compound Info	(S)-5-oxo-4-(6-(4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)piperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H50N8O7	1
1	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0069760 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)picolinamido)pentanoic acid Show/Hide	C36H48N6O7	2
1	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
2	Ki = 6.3 nM Bioactivity Info	TI LI LO TS
CP0507679 Compound Info	(4S)-4-[({4-[3-(Dimethylamino)-3-oxopropyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C32H43N5O7	1
1	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0521448 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-{[(4-ethoxypiperidin-1-yl)carbonyl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C34H45N5O9	1
1	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0522018 Compound Info	(4S)4-[({4-[(2-Methoxyethyl)methyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C31H43N5O7	1
1	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0439159 Compound Info	(S)-4-(6-(4-((ethylamino)methyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H49N7O6	1
1	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
CP0488878 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(piperidin-4-ylmethoxy)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C32H44N6O7	1
1	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
CP0529853 Compound Info	(S)-4-(6-(4-(2-methoxyethyl)piperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H47N7O7	1
1	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
CP0513915 Compound Info	(4S)4-({[4-({[Methyl(tetrahydrofuran-3-yl)mino]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H43N5O9	1
1	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
CP0541361 Compound Info	(4S)4-{[(4-{[(4-Methylpiperazin-1-yl)acetyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C37H53N7O7	1
1	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
CP0371894 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(2-methoxyethyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoicAcid Show/Hide	C29H39N5O7	1
1	Ki = 2.4 nM Bioactivity Info	TI LI LO TS
CP0500667 Compound Info	(4S)4-[({4-[4-(Hydroxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H45N5O7	1
1	Ki = 2.4 nM Bioactivity Info	TI LI LO TS
CP0522055 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(methoxyacetyl)iperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C33H45N5O8	1
1	Ki = 2.4 nM Bioactivity Info	TI LI LO TS
CP0526328 Compound Info	(4S)-4-[({4-[(Dimethylamino)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C30H39N5O7	1
1	Ki = 2.4 nM Bioactivity Info	TI LI LO TS
CP0441470 Compound Info	(S)-4-(6-(3-hydroxyazetidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C29H38N6O7	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0531198 Compound Info	(S)-4-(6-(4-(dimethylcarbamoyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H47N7O7	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0372041 Compound Info	(S)-4-(4-(3-hydroxyazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C30H39N5O7	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0497096 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(1-methylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C33H45N5O7	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0502329 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(2-piperidin-3-ylethoxy)pyridin-2-yl]carbonyl}amino)pentanoicAcid Show/Hide	C33H45N5O7	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0526329 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-[({4-[(1-methylpiperidin-4-yl)xy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxopentanoicAcid Show/Hide	C32H43N5O7	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0529854 Compound Info	(S)-4-(6-(4-(2-(dimethylamino)-2-oxoethyl)piperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N8O7	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0518877 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-(dimethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C34H46N6O7	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0532608 Compound Info	(S)-4-(4-((R)-3-(diethylcarbamoyl)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H50N6O7	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0429191 Compound Info	(4S)-4-{[(4-{[Ethyl(methyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C31H41N5O7	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0497097 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(methoxyacetyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid Show/Hide	C35H47N5O9	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0513916 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C37H52N6O6	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0513917 Compound Info	(4S)-4-{[(4-{[(3-Methoxypropyl)(methyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)-carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H45N5O8	1
1	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
CP0529850 Compound Info	(S)-4-(6-(4-(2-aminoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H47N7O6	1
1	Ki = 2.7 nM Bioactivity Info	TI LI LO TS
CP0529857 Compound Info	(S)-4-(6-(4-methylpiperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H43N7O6	1
1	Ki = 2.7 nM Bioactivity Info	TI LI LO TS
CP0510610 Compound Info	(4S)4-{[(4-{[(Isopropylamino)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C35H50N6O7	1
1	Ki = 2.7 nM Bioactivity Info	TI LI LO TS
CP0522056 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(methylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C32H44N6O6	1
1	Ki = 2.7 nM Bioactivity Info	TI LI LO TS
CP0494772 Compound Info	(S)-4-(6-(4-(2-(dimethylamino)ethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H51N7O6	1
1	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0503004 Compound Info	(S)-4-(6-(3-morpholinopropoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O8	1
1	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0135766 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)picolinamido)pentanoic acid Show/Hide	C37H50N6O7	2
1	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
2	Ki = 6.7 nM Bioactivity Info	TI LI LO TS
CP0447795 Compound Info	(S)-4-(4-(4-(2-aminoethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N6O6	1
1	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0532623 Compound Info	(S)-4-(4-(4-(2-(dimethylamino)acetyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H49N7O7	1
1	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0371899 Compound Info	(4S)-5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(piperidin-1-ylcarbonyl)pyridin-2-yl]carbonyl}amino)-pentanoic Acid Show/Hide	C33H43N5O7	1
1	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0507680 Compound Info	(4S)4-[({4-[(1-Acetylpiperidin-4-yl)oxy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-[4-(butoxycarbonyl)piperazin-1-yl]-5-oxopentanoicAcid Show/Hide	C33H43N5O9	1
1	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0520430 Compound Info	(4S)-4-({[4-(5-Hydroxypentyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C32H44N4O7	1
1	Ki = 2.8 nM Bioactivity Info	TI LI LO TS
CP0529851 Compound Info	(S)-4-(6-(4-morpholinopiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H49N7O7	1
1	Ki = 2.9 nM Bioactivity Info	TI LI LO TS
CP0537576 Compound Info	(S)-4-(6-(4-(dimethylcarbamoyl)piperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N8O7	1
1	Ki = 2.9 nM Bioactivity Info	TI LI LO TS
CP0374054 Compound Info	3-(3-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C29H30N6O4S	2
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
2	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0064676 Compound Info	(S)-4-(6-(4-(aminomethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H45N7O6	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0374044 Compound Info	(S)-4-(4-(4-(2-aminoethyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H47N7O6	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0510611 Compound Info	(4S)4-[({4-[(Morpholin-4-ylacetyl)mino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C36H50N6O8	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0520432 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(2-piperidin-4-ylethoxy)pyridin-2-yl]carbonyl}amino)pentanoicAcid Show/Hide	C33H45N5O7	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0506520 Compound Info	(S)-4-(6-(4-(2-(diethylamino)-2-oxoethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H53N7O7	1
1	Ki = 3.1 nM Bioactivity Info	TI LI LO TS
CP0452748 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxo-5-(4-propoxycarbonylpiperazin-1-yl)pentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 3.1 nM Bioactivity Info	TI LI LO TS
CP0463983 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{4-[(dimethylamino)ethyl]piperidin-1-yl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C34H48N6O6	1
1	Ki = 3.2 nM Bioactivity Info	TI LI LO TS
CP0383762 Compound Info	(4S)4-{[(4-{[(4-Methylpiperazin-1-yl)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C33H45N7O7	1
1	Ki = 3.2 nM Bioactivity Info	TI LI LO TS
CP0502656 Compound Info	(4S)-4-[({4-[(4-Methoxypiperidin-1-yl)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H45N5O8	1
1	Ki = 3.2 nM Bioactivity Info	TI LI LO TS
CP0507731 Compound Info	(S)-4-(4-(3-morpholinoazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H46N6O7	1
1	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
CP0373580 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-morpholin-4-yl-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C30H39N5O7	1
1	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
CP0470900 Compound Info	(4S)4-({[4-(4-Aminopiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoic Acid Show/Hide	C33H46N6O6	1
1	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
CP0470901 Compound Info	(4S)-4-[({4-[4-(Dimethylamino)butyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H47N5O6	1
1	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
CP0418165 Compound Info	(S)-4-(4-(4-carbamoylpiperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N7O7	1
1	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
CP0452735 Compound Info	(S)-4-(4-((R)-3-(2-(diethylamino)-2-oxoethoxy)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H52N6O8	1
1	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
CP0383877 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(piperidin-4-yloxy)yridin-2-yl]carbonyl}amino)entanoicAcid Show/Hide	C32H43N5O7	2
1	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.8 nM Bioactivity Info	TI LI LO TS
CP0383878 Compound Info	(4S)4-({[4-(4-Aminopiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-[4-(butoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C31H42N6O6	1
1	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
CP0494756 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(4-phenyl-6-(4-(pyrrolidine-1-carbonyl)piperidin-1-yl)pyrimidine-2-carboxamido)pentanoic acid Show/Hide	C36H49N7O7	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0531197 Compound Info	(S)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H51N7O7	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0371901 Compound Info	(4S)4-[({4-[(1-Acetylpiperidin-4-ylo)xy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid Show/Hide	C34H45N5O9	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0383880 Compound Info	(4S)-4-({[4-(4-Hydroxybutyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C31H42N4O7	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0494776 Compound Info	(S)-4-(6-(4-acetylpiperazin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N7O7	1
1	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
CP0371902 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(pyrrolidin-3-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid Show/Hide	C30H39N5O7	1
1	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
CP0507662 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(2-piperidin-2-ylethoxy)pyridin-2-yl]carbonyl}amino)pentanoicAcid Show/Hide	C33H45N5O7	1
1	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
CP0522061 Compound Info	(4S)-4-({[4-(3-Morpholin-4-yl-3-oxopropyl)-6-phenylpyridin-2-yl]carbonyl}amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H45N5O8	1
1	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
CP0528652 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-3-ylmethoxy)yridin-2-yl]carbonyl}amino)pentanoicAcid Show/Hide	C32H43N5O7	1
1	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
CP0463985 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-((ethylamino)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C34H48N6O6	1
1	Ki = 3.8 nM Bioactivity Info	TI LI LO TS
CP0520520 Compound Info	(4S)-4-({[4-(3-Hydroxypropyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C30H40N4O7	1
1	Ki = 3.8 nM Bioactivity Info	TI LI LO TS
CP0526330 Compound Info	(4S)4-[({4-[(1-Acetylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-[4-(butoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C34H45N5O8	1
1	Ki = 3.9 nM Bioactivity Info	TI LI LO TS
CP0463926 Compound Info	(2R,5S)-1-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)pyrrolidine-2,5-dicarboxamide Show/Hide	C31H33N7O3S	2
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
2	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0383882 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{4-[(methylamino)ethyl]piperidin-1-yl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C33H46N6O6	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0502341 Compound Info	(S)-4-(4-(4-((diethylamino)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H54N6O6	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0513913 Compound Info	(S)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H52N6O7	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0383881 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(2-methoxyethyl)methyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C30H41N5O7	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0491248 Compound Info	(4S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(pyrrolidin-3-ylmethylamino)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C31H43N7O6	1
1	Ki = 4.1 nM Bioactivity Info	TI LI LO TS
CP0383763 Compound Info	(4S)4-[({4-[(N,N-Dimethylglycyl)mino]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C35H50N6O7	1
1	Ki = 4.1 nM Bioactivity Info	TI LI LO TS
CP0473782 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(4-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)pyrimidine-2-carboxamido)pentanoic acid Show/Hide	C37H53N7O6	1
1	Ki = 4.2 nM Bioactivity Info	TI LI LO TS
CP0506319 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-4-ylmethoxy)pyridin-2-yl]carbonyl}amino)pentanoicAcid Show/Hide	C32H43N5O7	1
1	Ki = 4.2 nM Bioactivity Info	TI LI LO TS
CP0534319 Compound Info	(S)-4-(6-(4-((2-methoxyethoxy)methyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H50N6O8	1
1	Ki = 4.3 nM Bioactivity Info	TI LI LO TS
CP0383855 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-(isopropylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C35H48N6O7	1
1	Ki = 4.3 nM Bioactivity Info	TI LI LO TS
CP0513918 Compound Info	(4S)-4-({[4-(Morpholin-4-ylcarbonyl)-6-phenylpyridin-2-yl]carbonyl}amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C32H41N5O8	1
1	Ki = 4.4 nM Bioactivity Info	TI LI LO TS
CP0439240 Compound Info	(S)-4-(6-(2-hydroxyethylthio)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C28H37N5O7S	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0372048 Compound Info	(S)-4-(4-(4-(2-aminoethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H47N7O6	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0384054 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(1-isopropylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C35H49N5O7	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0470903 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(piperidin-4-ylmethoxy)pyridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C33H45N5O7	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0519138 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]methoxy}pyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C35H44F3N5O8	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0520405 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-({[6-phenyl-4-(piperidin-4-ylmethoxy)pyridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C34H47N5O7	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0502241 Compound Info	(4S)-5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(tetrahydro-2H-pyran-4-ylamino)carbonyl]pyridin-2-yl}carbonyl)amino]pentanoic Acid Show/Hide	C33H43N5O8	1
1	Ki = 4.6 nM Bioactivity Info	TI LI LO TS
CP0502653 Compound Info	(4S)4-[({4-[({[2-(Dimethylamino)2-oxoethyl]amino}carbonyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C36H51N7O8	1
1	Ki = 4.7 nM Bioactivity Info	TI LI LO TS
CP0529858 Compound Info	(S)-4-(6-(3-(dimethylamino)propylamino)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H45N7O6	1
1	Ki = 4.8 nM Bioactivity Info	TI LI LO TS
CP0372049 Compound Info	(S)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-(4-(hexyloxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C38H54N6O7	1
1	Ki = 4.8 nM Bioactivity Info	TI LI LO TS
CP0470079 Compound Info	(4S)4-[({4-[(Morpholin-4-ylcarbonyl)oxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C32H41N5O9	1
1	Ki = 4.8 nM Bioactivity Info	TI LI LO TS
CP0373538 Compound Info	(S)-4-(4-(4-(2-(dimethylamino)-2-oxoethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H49N7O7	1
1	Ki = 4.9 nM Bioactivity Info	TI LI LO TS
CP0371903 Compound Info	(4S)4-({[4-({[(3S)3-Methoxypyrrolidin-1-yl]carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H43N5O9	1
1	Ki = 4.9 nM Bioactivity Info	TI LI LO TS
CP0513919 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(4-hydroxybutoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C30H40N4O8	1
1	Ki = 4.9 nM Bioactivity Info	TI LI LO TS
CP0383619 Compound Info	(2S,4S)-1-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)-4-hydroxypyrrolidine-2-carboxylic acid Show/Hide	C30H31N5O4S	2
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
2	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0436664 Compound Info	(S)-4-(6-(4-methoxypiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H44N6O7	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0532615 Compound Info	(S)-4-(4-((S)-3-(2-(dimethylamino)-2-oxoethoxy)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H48N6O8	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0371904 Compound Info	(4S)4-[({4-[(1-Methylpiperidin-4-yl)xy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H45N5O7	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0507664 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(dimethylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C33H46N6O6	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0495649 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-(2H-tetrazol-5-yl)butanoyl]piperazine-1-carboxylate Show/Hide	C33H43N11O7	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0495650 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-cyclobutyloxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C35H45N7O9	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0513920 Compound Info	(4S)4-{[(4-{[1-(Ethylsulfonyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H47N5O9S	1
1	Ki = 5.1 nM Bioactivity Info	TI LI LO TS
CP0503003 Compound Info	(S)-4-(4-(2-methoxyethylamino)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C29H40N6O7	1
1	Ki = 5.2 nM Bioactivity Info	TI LI LO TS
CP0507732 Compound Info	(S)-5-oxo-4-(4-(4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H51N7O7	1
1	Ki = 5.2 nM Bioactivity Info	TI LI LO TS
CP0496642 Compound Info	(S)-4-(6-(4-(2-methoxyethoxy)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N6O8	1
1	Ki = 5.3 nM Bioactivity Info	TI LI LO TS
CP0427010 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-{[1-(ethylsulfonyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid Show/Hide	C34H47N5O9S	1
1	Ki = 5.3 nM Bioactivity Info	TI LI LO TS
CP0470904 Compound Info	(4S)4-[({4-[(1-Methylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H47N5O7	1
1	Ki = 5.3 nM Bioactivity Info	TI LI LO TS
CP0507665 Compound Info	(4S)4-{[(4-{[1-(2-Methoxyethyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C36H51N5O8	1
1	Ki = 5.3 nM Bioactivity Info	TI LI LO TS
CP0520406 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-{[1-(2-methoxyethyl)iperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid Show/Hide	C35H49N5O8	1
1	Ki = 5.3 nM Bioactivity Info	TI LI LO TS
CP0384056 Compound Info	(4S)-4-{[(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C35H48N6O7	1
1	Ki = 5.4 nM Bioactivity Info	TI LI LO TS
CP0372044 Compound Info	(4S)-4-(4-(3-aminopiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H44N6O6	1
1	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0542751 Compound Info	(S)-4-(4-(3-(dimethylamino)azetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H44N6O6	1
1	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0421852 Compound Info	(4S)4-[({4-[(1-Isopropylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C36H51N5O7	1
1	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0499275 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-piperidin-1-ylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C32H43N5O6	1
1	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0507666 Compound Info	(4S)4-{[(4-{[(Dimethylamino)carbonyl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C30H39N5O8	1
1	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0439749 Compound Info	(4S)4-{[(4,6-Diphenylpyridin-2-yl)carbonyl]amino}-5-[4-(3-methylphenyl)iperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C34H34N4O4	2
1	Ki = 5.7 nM Bioactivity Info	TI LI LO TS
2	Ki = 150 nM Bioactivity Info	TI LI LO TS
CP0439160 Compound Info	(S)-4-(6-((1-methylpiperidin-4-yl)methoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O7	1
1	Ki = 5.7 nM Bioactivity Info	TI LI LO TS
CP0407486 Compound Info	(4S)4-[({4-[(N-Methylglycyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C34H48N6O7	1
1	Ki = 5.7 nM Bioactivity Info	TI LI LO TS
CP0507667 Compound Info	(4S)4-[({4-[(2-Hydroxyethyl)amino]-6-phenylpyridin-2-yl}-carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid Show/Hide	C29H39N5O7	1
1	Ki = 5.7 nM Bioactivity Info	TI LI LO TS
CP0482443 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxo-5-(4-phenylmethoxycarbonylpiperazin-1-yl)pentanoic acid Show/Hide	C38H45N7O9	1
1	Ki = 5.7 nM Bioactivity Info	TI LI LO TS
CP0494775 Compound Info	(S)-4-(4-(4-carbamoylpiperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H42N8O7	1
1	Ki = 5.8 nM Bioactivity Info	TI LI LO TS
CP0513921 Compound Info	(4S)-4-{[(4-{[Butyl(methyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H45N5O7	1
1	Ki = 5.8 nM Bioactivity Info	TI LI LO TS
CP0520407 Compound Info	(4S)-4-[({4-[(4-Methylpiperazin-1-yl)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H44N6O7	1
1	Ki = 5.8 nM Bioactivity Info	TI LI LO TS
CP0528054 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(piperidin-1-ylcarbonyl)mino]pyridin-2-yl}carbonyl)amino]pentanoic acid Show/Hide	C37H52N6O7	1
1	Ki = 5.8 nM Bioactivity Info	TI LI LO TS
CP0514380 Compound Info	(S)-4-(4-(4-morpholinopiperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H49N7O7	1
1	Ki = 5.9 nM Bioactivity Info	TI LI LO TS
CP0372047 Compound Info	(S)-4-(4-(4-(2-(diethylamino)-2-oxoethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H53N7O7	1
1	Ki = 5.9 nM Bioactivity Info	TI LI LO TS
CP0523999 Compound Info	(S)-4-(4-(4-(dimethylcarbamoyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H47N7O7	1
1	Ki = 5.9 nM Bioactivity Info	TI LI LO TS
CP0452727 Compound Info	(4S)-5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-({[4-(3-methoxypropoxy)-6-phenylpyridin-2-yl]carbonyl}amino)-5-oxopentanoicAcid Show/Hide	C30H40N4O8	1
1	Ki = 5.9 nM Bioactivity Info	TI LI LO TS
CP0498716 Compound Info	(S)-4-(4-(4-(isopropylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H50N6O7	1
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0473491 Compound Info	(4S)5-Oxo-5-{4-[(pentylamino)carbonothioyl]piperazin-1-yl}-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C31H43N5O4S	1
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0489162 Compound Info	(4S)4-{[(4-{[(4-Ethoxypiperidin-1-yl)carbonyl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C35H47N5O9	1
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0384058 Compound Info	(4S)-4-{[(4-{[(3-Methoxypropyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C32H43N5O8	1
1	Ki = 6.1 nM Bioactivity Info	TI LI LO TS
CP0510710 Compound Info	(4S)4-({[4-(Acetylamino)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C33H45N5O7	1
1	Ki = 6.2 nM Bioactivity Info	TI LI LO TS
CP0498704 Compound Info	(S)-4-(4-(4-carbamoylpiperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N7O7	1
1	Ki = 6.3 nM Bioactivity Info	TI LI LO TS
CP0513912 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-(2-propoxyethyl)piperazin-1-yl)picolinamido)pentanoic acid Show/Hide	C36H52N6O7	1
1	Ki = 6.3 nM Bioactivity Info	TI LI LO TS
CP0507735 Compound Info	(S)-4-(4-(4-carbamoylpiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H44N6O7	1
1	Ki = 6.5 nM Bioactivity Info	TI LI LO TS
CP0542755 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(piperazin-1-yl)picolinamido)pentanoic acid Show/Hide	C31H42N6O6	1
1	Ki = 6.5 nM Bioactivity Info	TI LI LO TS
CP0384059 Compound Info	(4S)4-[({4-[4-(Methylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H46N6O6	1
1	Ki = 6.5 nM Bioactivity Info	TI LI LO TS
CP0520408 Compound Info	(4S)4-{[(4-{[1-(Ethoxycarbonyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoicAcid Show/Hide	C35H47N5O9	1
1	Ki = 6.5 nM Bioactivity Info	TI LI LO TS
CP0476883 Compound Info	butyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-hydroxypentanoyl]piperazine-1-carboxylate Show/Hide	C35H49N7O8	1
1	Ki = 6.5 nM Bioactivity Info	TI LI LO TS
CP0491245 Compound Info	(S)-4-(4-(4-(2-(dimethylamino)-2-oxoethyl)piperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N8O7	1
1	Ki = 6.8 nM Bioactivity Info	TI LI LO TS
CP0492722 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(3-hydroxypropoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C29H38N4O8	1
1	Ki = 6.9 nM Bioactivity Info	TI LI LO TS
CP0507668 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-3-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid Show/Hide	C31H41N5O7	1
1	Ki = 6.9 nM Bioactivity Info	TI LI LO TS
CP0372053 Compound Info	(4S)4-[({4-[4-(Aminomethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C33H46N6O6	2
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
2	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0496189 Compound Info	(4S)5-{4-[(Heptyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C29H38N4O6	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0513922 Compound Info	(4S)4-[({4-[(1-Isopropylpiperidin-4-yl)oxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C35H49N5O7	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0541511 Compound Info	(S)-4-(4-(4-(2-methoxyethoxy)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N6O8	1
1	Ki = 7.1 nM Bioactivity Info	TI LI LO TS
CP0463997 Compound Info	(S)-4-(4-(3-((methylamino)methyl)azetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H44N6O6	1
1	Ki = 7.1 nM Bioactivity Info	TI LI LO TS
CP0523998 Compound Info	(4S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(3-(pyrrolidin-1-ylmethyl)piperidin-1-yl)picolinamido)pentanoic acid Show/Hide	C37H52N6O6	1
1	Ki = 7.3 nM Bioactivity Info	TI LI LO TS
CP0488032 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C33H43N7O9	1
1	Ki = 7.3 nM Bioactivity Info	TI LI LO TS
CP0396900 Compound Info	(S)-4-(4-(4-methoxypiperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H44N6O7	1
1	Ki = 7.4 nM Bioactivity Info	TI LI LO TS
CP0494773 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(4-phenyl-6-(4-(pyrrolidin-1-yl)piperidin-1-yl)pyrimidine-2-carboxamido)pentanoic acid Show/Hide	C35H49N7O6	1
1	Ki = 7.4 nM Bioactivity Info	TI LI LO TS
CP0520409 Compound Info	(4S)4-{[(4-{[1-(Ethylsulfonyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C35H49N5O9S	1
1	Ki = 7.4 nM Bioactivity Info	TI LI LO TS
CP0529852 Compound Info	(S)-4-(6-(4-methylpiperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H44N6O6	1
1	Ki = 7.5 nM Bioactivity Info	TI LI LO TS
CP0470073 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(4-((diethylamino)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C36H52N6O6	1
1	Ki = 7.5 nM Bioactivity Info	TI LI LO TS
CP0520410 Compound Info	(4S)-4-({[4-(Aminocarbonyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid Show/Hide	C28H35N5O7	1
1	Ki = 7.5 nM Bioactivity Info	TI LI LO TS
CP0427013 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(ethylsulfonyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid Show/Hide	C33H45N5O9S	1
1	Ki = 7.6 nM Bioactivity Info	TI LI LO TS
CP0470909 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(ethoxycarbonyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid Show/Hide	C35H47N5O9	1
1	Ki = 7.6 nM Bioactivity Info	TI LI LO TS
CP0492725 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(pyrrolidin-1-ylcarbonyl)oxy]pyridin-2-yl}carbonyl)amino]pentanoic Acid Show/Hide	C32H41N5O8	1
1	Ki = 7.7 nM Bioactivity Info	TI LI LO TS
CP0477009 Compound Info	butyl 4-[2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]acetyl]piperazine-1-carboxylate Show/Hide	C32H43N7O7	1
1	Ki = 7.7 nM Bioactivity Info	TI LI LO TS
CP0480982 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(2R)-4-ethoxycarbonyl-2-methylpiperazin-1-yl]-5-oxopentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 7.7 nM Bioactivity Info	TI LI LO TS
CP0507734 Compound Info	(S)-4-(4-(4-(methylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H46N6O7	1
1	Ki = 7.9 nM Bioactivity Info	TI LI LO TS
CP0514325 Compound Info	(4S)4-{[(4-Ethoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C29H38N4O7	1
1	Ki = 7.9 nM Bioactivity Info	TI LI LO TS
CP0527155 Compound Info	(4S)-4-{[(4-{[(2-Methoxyethyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C31H41N5O8	1
1	Ki = 7.9 nM Bioactivity Info	TI LI LO TS
CP0402203 Compound Info	3-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-ylamino)propanoic acid Show/Hide	C28H29N5O3S	2
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
2	Ki = 122 nM Bioactivity Info	TI LI LO TS
CP0372051 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)picolinamido)pentanoic acid Show/Hide	C38H54N6O6	1
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0501494 Compound Info	(4S)5-{4-[(Butylamino)carbonothioyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C30H41N5O4S	1
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0439244 Compound Info	(S)-4-(4-(4-((2-methoxyethoxy)methyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H50N6O8	1
1	Ki = 8.1 nM Bioactivity Info	TI LI LO TS
CP0532630 Compound Info	(S)-4-(4-(4-(2-methoxyethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N6O7	1
1	Ki = 8.3 nM Bioactivity Info	TI LI LO TS
CP0528068 Compound Info	(4S)-4-({[4-(4-Methoxybutyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C32H44N4O7	1
1	Ki = 8.3 nM Bioactivity Info	TI LI LO TS
CP0071250 Compound Info	(S)-4-(6-(4-(methoxymethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O7	1
1	Ki = 8.4 nM Bioactivity Info	TI LI LO TS
CP0439243 Compound Info	(S)-4-(4-(4-(2-methoxyethyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N6O7	1
1	Ki = 8.4 nM Bioactivity Info	TI LI LO TS
CP0506502 Compound Info	(S)-4-(4-(4-aminopiperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H43N7O6	1
1	Ki = 8.4 nM Bioactivity Info	TI LI LO TS
CP0507733 Compound Info	(S)-4-(4-(4-(3-(dimethylamino)propyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H53N7O6	1
1	Ki = 8.4 nM Bioactivity Info	TI LI LO TS
CP0477639 Compound Info	(4S)4-({[4-(2-Aminoethoxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoicAcid Show/Hide	C30H41N5O7	1
1	Ki = 8.4 nM Bioactivity Info	TI LI LO TS
CP0502642 Compound Info	(4S)-4-({[4-(3-Methoxypropyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C31H42N4O7	1
1	Ki = 8.4 nM Bioactivity Info	TI LI LO TS
CP0542754 Compound Info	(S)-4-(4-(4-(2-(dimethylamino)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H51N7O6	1
1	Ki = 8.5 nM Bioactivity Info	TI LI LO TS
CP0541363 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(tetrahydro-2H-pyran-4-ylcarbonyl)amino]pyridin-2-yl}carbonyl)amino]pentanoic acid Show/Hide	C37H51N5O8	1
1	Ki = 8.5 nM Bioactivity Info	TI LI LO TS
CP0492726 Compound Info	(4S)-4-({[4-(Cyclohexylmethyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H46N4O6	1
1	Ki = 8.6 nM Bioactivity Info	TI LI LO TS
CP0522022 Compound Info	(4S)-4-({[4-({[3-(Dimethylamino)propyl](methyl)amino}carbonyl)-6-phenylpyridin-2-yl]carbonyl}amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H48N6O7	1
1	Ki = 8.6 nM Bioactivity Info	TI LI LO TS
CP0502243 Compound Info	(4S)4-({[4-(2-Aminoethoxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid Show/Hide	C29H39N5O7	1
1	Ki = 8.8 nM Bioactivity Info	TI LI LO TS
CP0470071 Compound Info	(S)-4-(4-(4-(2-(methylsulfonyl)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N6O8S	1
1	Ki = 8.9 nM Bioactivity Info	TI LI LO TS
CP0477640 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}-amino)pentanoic Acid Show/Hide	C36H50N6O6	1
1	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0502644 Compound Info	(4S)5-{4-[(Ethylamino)carbonothioyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C28H37N5O4S	1
1	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0447512 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(trifluoroacetyl)amino]pyridin-2-yl}carbonyl)amino]pentanoic acid Show/Hide	C33H42F3N5O7	1
1	Ki = 9.1 nM Bioactivity Info	TI LI LO TS
CP0383767 Compound Info	(4S)4-{[(4-{[(4-Methoxypiperidin-1-yl)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C38H54N6O8	1
1	Ki = 9.2 nM Bioactivity Info	TI LI LO TS
CP0039796 Compound Info	(S)-4-(4-(4-(aminomethyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H45N7O6	1
1	Ki = 9.4 nM Bioactivity Info	TI LI LO TS
CP0498879 Compound Info	(S)-4-(6-(1-isopropylpiperidin-4-ylamino)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H49N7O6	1
1	Ki = 9.4 nM Bioactivity Info	TI LI LO TS
CP0522023 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-({[6-phenyl-4-(piperidin-4-yloxy)yridin-2-yl]carbonyl}amino)entanoicAcid Show/Hide	C33H45N5O7	1
1	Ki = 9.4 nM Bioactivity Info	TI LI LO TS
CP0522024 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-{[1-(2-methoxyethyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid Show/Hide	C34H47N5O8	1
1	Ki = 9.4 nM Bioactivity Info	TI LI LO TS
CP0421639 Compound Info	(4S)4-[({4-[(2-Methoxyethyl)mino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid Show/Hide	C30H41N5O7	1
1	Ki = 9.8 nM Bioactivity Info	TI LI LO TS
CP0532618 Compound Info	(4S)-4-(4-(3-(acetamidomethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H48N6O7	1
1	Ki = 9.9 nM Bioactivity Info	TI LI LO TS
CP0384073 Compound Info	(4S)4-{[(4-{[1-(2-Methoxyethyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C35H49N5O8	1
1	Ki = 9.9 nM Bioactivity Info	TI LI LO TS
CP0455420 Compound Info	(4S)4-({[4-(2-Methoxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C30H40N4O8	2
1	Ki = 9.9 nM Bioactivity Info	TI LI LO TS
2	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0531199 Compound Info	(S)-4-(4-(4-(2-hydroxyethoxy)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O8	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0372043 Compound Info	(4S)-5-oxo-4-(4-(3-((2-oxopyrrolidin-1-yl)methyl)piperidin-1-yl)-6-phenylpicolinamido)-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H50N6O7	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0421989 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-(pyrrolidine-1-carbonyl)piperazin-1-yl)picolinamido)pentanoic acid Show/Hide	C36H49N7O7	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0402062 Compound Info	(4S)4-({[4-(4-Aminopiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C29H38N6O6	2
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
2	Ki = 27 nM Bioactivity Info	TI LI LO TS
CP0402063 Compound Info	(4S)-4-[({4-[(Methylamino)carbonyl]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C29H37N5O7	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0514326 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(tetrahydro-2H-pyran-4-yloxy)yridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C31H40N4O8	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0514327 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[(1-isopropylpiperidin-4-yl)xy]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C34H47N5O7	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0519066 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]methoxy}pyridin-2-yl)carbonyl]-amino}pentanoic Acid Show/Hide	C34H42F3N5O8	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0519069 Compound Info	(4S)4-({[4-(4-Morpholin-4-ylpiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C36H50N6O7	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0494758 Compound Info	(S)-4-(6-(4-(2-methoxyethyl)piperidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H48N6O7	1
1	Ki = 10.2 nM Bioactivity Info	TI LI LO TS
CP0439750 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C27H34N4O6	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0510214 Compound Info	(4S)4-({[4-(4-Hydroxypiperidin-1-yl)6-phenylpyridin-2-yl]-carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid Show/Hide	C32H43N5O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0424414 Compound Info	(S)-4-(4-(4-((ethylamino)methyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H49N7O6	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0424415 Compound Info	(S)-4-(4-morpholino-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C30H40N6O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0488875 Compound Info	(S)-4-(4-(4-((methylamino)methyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H47N7O6	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0488879 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-(piperidin-4-yloxy)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C30H40N6O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0494777 Compound Info	(S)-4-(4-(4-methylpiperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H43N7O6	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0502771 Compound Info	(S)-4-(4-(3-morpholinopropoxy)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O8	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0372052 Compound Info	(S)-4-(4-(4-(2-methoxyethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H49N5O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0532621 Compound Info	(4S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(3-(pyrrolidin-1-yl)piperidin-1-yl)picolinamido)pentanoic acid Show/Hide	C36H50N6O6	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0427021 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(piperidin-1-ylcarbonyl)oxy]pyridin-2-yl}carbonyl)mino]-pentanoic Acid Show/Hide	C33H43N5O8	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0469876 Compound Info	(4S)4-[({4-[(Ethoxycarbonyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C34H47N5O8	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0477641 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(tetrahydro-2H-pyran-4-ylmethoxy)yridin-2-yl]carbonyl}-amino)entanoic Acid Show/Hide	C32H42N4O8	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0514328 Compound Info	(4S)4-{[(4-Hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C27H34N4O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0522026 Compound Info	(4S)4-{[(4-{[1-(Methoxyacetyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C34H47N5O8	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0522027 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-[({4-[(2-methoxyethyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C31H43N5O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0522030 Compound Info	(4S)-5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(propylamino)carbonyl]pyridin-2-yl}carbonyl)amino]-pentanoic Acid Show/Hide	C31H41N5O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0522032 Compound Info	(4S)-4-{[(4-{[Methyl(1-methylpiperidin-4-yl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)-carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C35H48N6O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0528069 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-2-ylmethoxy)yridin-2-yl]carbonyl}amino)entanoic Acid Show/Hide	C32H43N5O7	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0513926 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-4-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid Show/Hide	C31H41N5O7	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0089675 Compound Info	(S)-4-(4-(4-(methoxymethyl)piperidin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O7	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0529860 Compound Info	(S)-4-(4-((1-methylpiperidin-4-yl)methoxy)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O7	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0537587 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(2-methoxyethoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C28H37N5O8	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0541516 Compound Info	(S)-4-(4-(4-(2-methoxyethyl)piperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H47N7O7	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0372046 Compound Info	(S)-4-(4-(4-(diethylcarbamoyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H51N7O7	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0383891 Compound Info	(S)-4-(4-(4-(2-(dimethylamino)ethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C36H52N6O6	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0498714 Compound Info	(S)-4-(4-(4-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(propoxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H48N6O7	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0421677 Compound Info	4S)4-{[(4-{[1-(Methoxyacetyl)piperidin-4-yl]methoxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid Show/Hide	C36H49N5O9	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0477642 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-({[6-phenyl-4-(propylamino)pyridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C30H41N5O6	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0513927 Compound Info	(4S)-4-[({4-[3-(Isobutylamino)propyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H49N5O6	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0522034 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]oxy}pyridin-2-yl)carbonyl]-amino}pentanoic Acid Show/Hide	C33H40F3N5O8	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0470072 Compound Info	(S)-4-(4-(4-(2-hydroxyethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N6O7	1
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0513907 Compound Info	4-(4-(3-hydroxypyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H41N5O7	1
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0519074 Compound Info	(4S)-4-[({4-[(Ethylamino)carbonyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C30H39N5O7	1
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0431499 Compound Info	(4S)4-[({4-[4-(Aminomethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoicAcid Show/Hide	C30H40N6O6	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0492797 Compound Info	(4S)5-{4-[(Octyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C30H40N4O6	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0529855 Compound Info	(S)-4-(4-(4-(dimethylcarbamoyl)piperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H46N8O7	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0519076 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-({[4-(2-methoxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C31H42N4O8	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0140474 Compound Info	AR-C126532XX Show/Hide	C23H28F2N6O4S	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0489633 Compound Info	(S)-4-(4,6-diphenylpicolinamido)-5-oxo-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid Show/Hide	C30H32N4O6	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0545695 Compound Info	(S)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H43N5O8S	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0514381 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-((1-methylpiperidin-4-yl)methoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C32H44N6O7	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0381097 Compound Info	(4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H47N5O7	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0533227 Compound Info	(S)-4-(4-(4-methylpiperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H44N6O6	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0502670 Compound Info	(4S)4-{[(4,6-Diphenylpyridin-2-yl)carbonyl]amino}-5-[4-(ethoxycarbonyl)iperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C30H32N4O6	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0513928 Compound Info	(4S)4-({[4-(4-Methoxypiperidin-1-yl)6-phenylpyridin-2-yl]-carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid Show/Hide	C33H45N5O7	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0522039 Compound Info	(4S)5-{4-[(2-Cyclopropylethoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C27H32N4O6	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0514383 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-(piperidin-4-ylmethoxy)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C31H42N6O7	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0372045 Compound Info	(S)-4-(4-((R)-3-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N5O7	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0383854 Compound Info	(S)-4-(4-(4-isobutyrylpiperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H48N6O7	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0405504 Compound Info	(S)-4-(6-(cyclopentylthio)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H41N5O6S	1
1	Ki = 17 nM Bioactivity Info	TI LI LO TS
CP0522019 Compound Info	(4S)-4-(4-(3-carbamoylpiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H44N6O7	1
1	Ki = 17 nM Bioactivity Info	TI LI LO TS
CP0519079 Compound Info	(4S)4-({[4-(4-Aminopiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-pentanoic Acid Show/Hide	C32H44N6O6	1
1	Ki = 17 nM Bioactivity Info	TI LI LO TS
CP0489634 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(methoxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C31H41N5O7	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0505736 Compound Info	(4S)4-[({4-[4-(Aminomethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoic Acid Show/Hide	C34H48N6O6	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0509344 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(2-methoxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C29H38N4O8	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0401972 Compound Info	(S)-4-(4-((S)-3-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N5O7	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0421678 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-propoxypyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C30H40N4O7	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0520521 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(4,4,4-trifluorobutoxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C26H29F3N4O6	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0528070 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-({[4-(2-hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C30H40N4O8	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0374052 Compound Info	(R)-biphenyl-4-yl(4-(2-(2,3-dihydroxypropylamino)-6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)methanone Show/Hide	C28H31N5O3S	2
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
2	Ki = 75 nM Bioactivity Info	TI LI LO TS
CP0494779 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(1-isopropylpiperidin-4-yloxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C33H46N6O7	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0502769 Compound Info	(S)-4-(4-(cyclopentylmethylamino)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H43N7O6	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0522062 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]oxy}pyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C34H42F3N5O8	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0413946 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylmethylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0402066 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(2-hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid Show/Hide	C28H36N4O8	2
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
2	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0514329 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-{[1-(ethoxycarbonyl)iperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]-amino}-5-oxopentanoic Acid Show/Hide	C34H45N5O9	1
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0526321 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-{[(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C28H36N4O7	1
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0534169 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclopentylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0372042 Compound Info	4-(4-(3-(hydroxymethyl)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N5O7	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0439239 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(2-phenyl-6-(2,2,2-trifluoroethylthio)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C28H34F3N5O6S	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0529856 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(4-phenyl-6-(piperazin-1-yl)pyrimidine-2-carboxamido)pentanoic acid Show/Hide	C30H41N7O6	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0452728 Compound Info	(4S)-4-(4-(3-(methoxymethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H47N5O7	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0470070 Compound Info	(S)-4-(4-(4-acetylpiperazin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H44N6O7	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0502671 Compound Info	(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[4-(propoxymethyl)piperidin-1-yl]pyridin-2-yl}carbonyl)amino]pentanoic Acid Show/Hide	C36H51N5O7	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0513929 Compound Info	(4S)4-[({4-[4-(Dimethylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H48N6O6	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0513930 Compound Info	(4S)-4-[({4-[3-(Diethylamino)propyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H49N5O6	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0565821 Compound Info	(4S)-5-[4-(butoxycarbonylamino)piperidin-1-yl]-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C36H49N7O9	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0431500 Compound Info	(S)-4-(4-(diethylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C28H37N5O6	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0488003 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-(methanesulfonamido)butanoyl]piperazine-1-carboxylate Show/Hide	C33H46N8O9S	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0523454 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-hydroxybutanoyl]piperazine-1-carboxylate Show/Hide	C32H43N7O8	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0534172 Compound Info	ELINOGREL Show/Hide	C20H15ClFN5O5S2	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0524030 Compound Info	(S)-5-(4-(hexyloxycarbonyl)piperazin-1-yl)-4-(4-(4-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C33H45N5O7	1
1	Ki = 24 nM Bioactivity Info	TI LI LO TS
CP0532610 Compound Info	(4S)-4-[[4-[(3R)-3-(dimethylcarbamoyl)pyrrolidin-1-yl]-6-phenylpyridine-2-carbonyl]amino]-5-oxo-5-(4-pentoxycarbonylpiperazin-1-yl)pentanoic acid Show/Hide	C34H46N6O7	1
1	Ki = 24 nM Bioactivity Info	TI LI LO TS
CP0498718 Compound Info	(S)-4-(4-(4-(acetamidomethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C35H48N6O7	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0538545 Compound Info	(4S)4-[({4-[(Methoxyacetyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C34H47N5O8	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0485240 Compound Info	(S)-4-(4-(benzylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C31H35N5O6	1
1	Ki = 26 nM Bioactivity Info	TI LI LO TS
CP0502339 Compound Info	(4S)-4-(4-(3-(diethylcarbamoyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C37H52N6O7	1
1	Ki = 26 nM Bioactivity Info	TI LI LO TS
CP0532612 Compound Info	(4S)-4-[[4-[(3S)-3-(dimethylcarbamoyl)pyrrolidin-1-yl]-6-phenylpyridine-2-carbonyl]amino]-5-oxo-5-(4-pentoxycarbonylpiperazin-1-yl)pentanoic acid Show/Hide	C34H46N6O7	1
1	Ki = 26 nM Bioactivity Info	TI LI LO TS
CP0384078 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-[4-(propoxycarbonyl)iperazin-1-yl]pentanoic Acid Show/Hide	C25H30N4O6	1
1	Ki = 27 nM Bioactivity Info	TI LI LO TS
CP0374051 Compound Info	[4-[6-ethyl-2-(3-hydroxyazetidin-1-yl)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]-(4-phenylphenyl)methanone Show/Hide	C28H29N5O2S	2
1	Ki = 27 nM Bioactivity Info	TI LI LO TS
2	Ki = 297 nM Bioactivity Info	TI LI LO TS
CP0501055 Compound Info	(S)-4-(6-(2-(diethylamino)ethoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H46N6O7	1
1	Ki = 27 nM Bioactivity Info	TI LI LO TS
CP0376803 Compound Info	(4S)-4-[[5-[2-[(2S)-2-[cyclobutyl(methyl)carbamoyl]pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 27 nM Bioactivity Info	TI LI LO TS
CP0404884 Compound Info	(S)-4-(4-(benzyloxy)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C31H34N4O7	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0421646 Compound Info	(4S)5-{4-[(Cyclobutylmethoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C27H32N4O6	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0421648 Compound Info	(4S)4-({[4-(Benzyloxy)6-phenylpyridin-2-yl]carbonyl}amino)5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C31H34N4O7	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0505737 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C26H32N4O6	1
1	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0452578 Compound Info	[4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]-(4-phenylphenyl)methanone Show/Hide	C25H24N4OS	1
1	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0415571 Compound Info	(S)-4-(4-(4-acetylpiperazin-1-yl)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N7O7	1
1	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0401974 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-propylpiperazin-1-yl)picolinamido)pentanoic acid Show/Hide	C34H48N6O6	1
1	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0413943 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[4-(3-methoxyphenyl)piperazin-1-yl]-5-oxopentanoic acid Show/Hide	C37H45N7O8	1
1	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0455310 Compound Info	1-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)piperidine-3-carboxamide Show/Hide	C31H34N6O2S	2
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
2	Ki = 203 nM Bioactivity Info	TI LI LO TS
CP0441473 Compound Info	(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(4-phenyl-6-(piperidin-4-ylmethoxy)pyrimidine-2-carboxamido)pentanoic acid Show/Hide	C32H44N6O7	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0373535 Compound Info	4-(4-(3-(methoxymethyl)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H45N5O7	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0498703 Compound Info	(4S)-4-(4-(3-methoxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C33H45N5O7	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0489635 Compound Info	(4S)4-({[4-(2-Hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid Show/Hide	C29H38N4O8	2
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
2	Ki = 32 nM Bioactivity Info	TI LI LO TS
CP0513935 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-{[(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoicAcid Show/Hide	C26H32N4O7	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0520475 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-[({4-[4-(methoxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C35H49N5O7	1
1	Ki = 33 nM Bioactivity Info	TI LI LO TS
CP0491191 Compound Info	(4S)5-{4-[(3-Methylbutoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C27H34N4O6	1
1	Ki = 33 nM Bioactivity Info	TI LI LO TS
CP0376802 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-phenylpyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid Show/Hide	C34H40N6O8	1
1	Ki = 33 nM Bioactivity Info	TI LI LO TS
CP0481518 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C33H44N6O6	1
1	Ki = 34 nM Bioactivity Info	TI LI LO TS
CP0485242 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-({[4-(methylamino)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid Show/Hide	C25H31N5O6	1
1	Ki = 35 nM Bioactivity Info	TI LI LO TS
CP0447582 Compound Info	[4-[6-ethyl-2-(3-hydroxypyrrolidin-1-yl)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]-(4-phenylphenyl)methanone Show/Hide	C29H31N5O2S	2
1	Ki = 35 nM Bioactivity Info	TI LI LO TS
2	Ki = 241 nM Bioactivity Info	TI LI LO TS
CP0491247 Compound Info	(S)-4-(4-(1-isopropylpiperidin-4-ylamino)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C34H49N7O6	1
1	Ki = 35 nM Bioactivity Info	TI LI LO TS
CP0439752 Compound Info	(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-{[(4-butoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C30H40N4O7	2
1	Ki = 35 nM Bioactivity Info	TI LI LO TS
2	Ki = 36 nM Bioactivity Info	TI LI LO TS
CP0485243 Compound Info	(S)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxo-5-(4-(hexyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H45N5O8S	1
1	Ki = 36 nM Bioactivity Info	TI LI LO TS
CP0457546 Compound Info	3-(3-(6-ethyl-4-(4-isobutyrylpiperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C20H28N6O4S	2
1	Ki = 36 nM Bioactivity Info	TI LI LO TS
2	Ki = 46 nM Bioactivity Info	TI LI LO TS
CP0401572 Compound Info	3-(3-(6-ethyl-4-(4-(5-phenylpicolinoyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C28H29N7O4S	2
1	Ki = 37 nM Bioactivity Info	TI LI LO TS
2	Ki = 161 nM Bioactivity Info	TI LI LO TS
CP0415689 Compound Info	[4-[6-ethyl-2-(2-hydroxyethylamino)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]-(4-phenylphenyl)methanone Show/Hide	C27H29N5O2S	2
1	Ki = 37 nM Bioactivity Info	TI LI LO TS
2	Ki = 163 nM Bioactivity Info	TI LI LO TS
CP0498880 Compound Info	(S)-4-(4-(3-(dimethylamino)propylamino)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C31H45N7O6	1
1	Ki = 38 nM Bioactivity Info	TI LI LO TS
CP0502641 Compound Info	(4S)4-{[(4-Butoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-[4-(ethoxycarbonyl)iperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C28H36N4O7	2
1	Ki = 39 nM Bioactivity Info	TI LI LO TS
2	Ki = 60 nM Bioactivity Info	TI LI LO TS
CP0470110 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-morpholin-4-yl-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C28H35N5O7	1
1	Ki = 39 nM Bioactivity Info	TI LI LO TS
CP0439753 Compound Info	(S)-5-(4-((2-cyclopentylethoxy)carbonyl)piperazin-1-yl)-4-(4-(4-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C34H45N5O7	1
1	Ki = 40 nM Bioactivity Info	TI LI LO TS
CP0565820 Compound Info	(4S)-5-(4-benzoylpiperidin-1-yl)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C38H44N6O8	1
1	Ki = 40 nM Bioactivity Info	TI LI LO TS
CP0523457 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(tert-butylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C33H45N7O9	1
1	Ki = 41 nM Bioactivity Info	TI LI LO TS
CP0421649 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-({[4-(4-hydroxypiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C29H37N5O7	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0473834 Compound Info	(S)-4-(6-(tert-butylthio)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C30H41N5O6S	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0502643 Compound Info	(4S)5-{4-[(3,3-Dimethylbutoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C28H36N4O6	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0541364 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(propylamino)carbonothioyl]piperazin-1-yl}pentanoic acid Show/Hide	C29H39N5O4S	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0376801 Compound Info	ethyl 4-[(2S)-4-acetamido-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]butanoyl]piperazine-1-carboxylate Show/Hide	C34H46N8O8	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0500038 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)azetidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C32H41N7O9	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0383988 Compound Info	(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C28H36N4O6	1
1	Ki = 43 nM Bioactivity Info	TI LI LO TS
CP0499358 Compound Info	(4S)4-({[4-({[4-(Methoxymethyl)piperidin-1-yl]carbonyl}amino)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C39H56N6O8	1
1	Ki = 43 nM Bioactivity Info	TI LI LO TS
CP0514338 Compound Info	(4S)5-{4-[(Cyclohexyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C28H34N4O6	1
1	Ki = 44 nM Bioactivity Info	TI LI LO TS
CP0383989 Compound Info	(4S)4-({[4-({[Methyl(tetrahydro-2H-pyran-4-ylmethyl)mino]-carbonyl}oxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C35H47N5O9	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0514339 Compound Info	(4S)4-({[4-(Dimethylamino)6-phenylpyridin-2-yl]carbonyl}-amino)5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C26H33N5O6	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0514340 Compound Info	(4S)4-({[4-(Dipropylamino)6-phenylpyridin-2-yl]carbonyl}-amino)5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C30H41N5O6	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0489116 Compound Info	(4S)5-{4-[(Cyclopentylmethoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C28H34N4O6	1
1	Ki = 46 nM Bioactivity Info	TI LI LO TS
CP0439260 Compound Info	(S)-4-(4-(4-(2-(dimethylamino)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C32H45N7O6	1
1	Ki = 47 nM Bioactivity Info	TI LI LO TS
CP0383990 Compound Info	(4S)5-{4-[(Cyclopentyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C27H32N4O6	1
1	Ki = 47 nM Bioactivity Info	TI LI LO TS
CP0439754 Compound Info	(S)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C28H37N5O8S	1
1	Ki = 48 nM Bioactivity Info	TI LI LO TS
CP0476884 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-3-(methanesulfonamido)propanoyl]piperazine-1-carboxylate Show/Hide	C32H44N8O9S	1
1	Ki = 48 nM Bioactivity Info	TI LI LO TS
CP0428925 Compound Info	(4S)4-{[(4-Butoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C31H42N4O7	1
1	Ki = 49 nM Bioactivity Info	TI LI LO TS
CP0523455 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(3R)-4-ethoxycarbonyl-3-methylpiperazin-1-yl]-5-oxopentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 51 nM Bioactivity Info	TI LI LO TS
CP0489117 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(hydroxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C30H39N5O7	1
1	Ki = 54 nM Bioactivity Info	TI LI LO TS
CP0541365 Compound Info	(4S)5-{4-[(Hexylamino)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C32H45N5O5	1
1	Ki = 54 nM Bioactivity Info	TI LI LO TS
CP0480981 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(2S)-4-ethoxycarbonyl-2-methylpiperazin-1-yl]-5-oxopentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 54 nM Bioactivity Info	TI LI LO TS
CP0529861 Compound Info	(4S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(2-phenyl-6-((tetrahydrofuran-2-yl)methoxy)pyrimidine-4-carboxamido)pentanoic acid Show/Hide	C30H39N5O8	1
1	Ki = 55 nM Bioactivity Info	TI LI LO TS
CP0501495 Compound Info	(4S)5-Oxo-5-{4-[(pentylamino)carbonyl]piperazin-1-yl}-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C31H43N5O5	1
1	Ki = 55 nM Bioactivity Info	TI LI LO TS
CP0413944 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(5-methyl-1H-imidazol-2-yl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C32H40N8O8	1
1	Ki = 56 nM Bioactivity Info	TI LI LO TS
CP0413945 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(piperidine-1-carbonyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 56 nM Bioactivity Info	TI LI LO TS
CP0553487 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(propan-2-ylcarbamoyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid Show/Hide	C32H43N7O9	1
1	Ki = 56 nM Bioactivity Info	TI LI LO TS
CP0513937 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C24H28N4O7	1
1	Ki = 62 nM Bioactivity Info	TI LI LO TS
CP0497468 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(propylamino)pyridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C27H35N5O6	1
1	Ki = 64 nM Bioactivity Info	TI LI LO TS
CP0507705 Compound Info	(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C35H48N6O6	1
1	Ki = 64 nM Bioactivity Info	TI LI LO TS
CP0376805 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(propylcarbamoyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid Show/Hide	C32H43N7O9	1
1	Ki = 66 nM Bioactivity Info	TI LI LO TS
CP0421650 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-4-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid Show/Hide	C29H37N5O7	1
1	Ki = 68 nM Bioactivity Info	TI LI LO TS
CP0439267 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(3-hydroxypropoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid Show/Hide	C27H34N4O8	1
1	Ki = 68 nM Bioactivity Info	TI LI LO TS
CP0457545 Compound Info	3-(3-(4-(4-(2-(3,4-difluorophenyl)acetyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C24H26F2N6O4S	2
1	Ki = 68 nM Bioactivity Info	TI LI LO TS
2	Ki = 140 nM Bioactivity Info	TI LI LO TS
CP0545720 Compound Info	(S)-4-(4-(4-(aminomethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-(4-((2-cyclopentylethoxy)carbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C35H48N6O6	1
1	Ki = 69 nM Bioactivity Info	TI LI LO TS
CP0514341 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(3-methoxypropoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C28H36N4O8	1
1	Ki = 69 nM Bioactivity Info	TI LI LO TS
CP0439238 Compound Info	(S)-4-(6-(cyclohexylthio)-2-phenylpyrimidine-4-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H43N5O6S	1
1	Ki = 70 nM Bioactivity Info	TI LI LO TS
CP0381619 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxo-5-(4-phenoxycarbonylpiperazin-1-yl)pentanoic acid Show/Hide	C37H43N7O9	1
1	Ki = 71 nM Bioactivity Info	TI LI LO TS
CP0427127 Compound Info	(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(2-(diethylamino)ethoxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C31H44N6O7	1
1	Ki = 72 nM Bioactivity Info	TI LI LO TS
CP0439268 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(piperidin-4-ylmethoxy)pyridin-2-yl]carbonyl}amino)pentanoic Acid Show/Hide	C30H39N5O7	1
1	Ki = 76 nM Bioactivity Info	TI LI LO TS
CP0373277 Compound Info	[4-[6-ethyl-2-(3-hydroxypropylamino)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]-(4-phenylphenyl)methanone Show/Hide	C28H31N5O2S	2
1	Ki = 78 nM Bioactivity Info	TI LI LO TS
2	Ki = 441 nM Bioactivity Info	TI LI LO TS
CP0421651 Compound Info	(4S)5-{4-[(But-3-yn-1-yloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C26H28N4O6	1
1	Ki = 79 nM Bioactivity Info	TI LI LO TS
CP0389568 Compound Info	(S)-5-(4-((2-cyclopentylethoxy)carbonyl)piperazin-1-yl)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C33H45N5O8S	1
1	Ki = 80 nM Bioactivity Info	TI LI LO TS
CP0507228 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(3S)-4-ethoxycarbonyl-3-methylpiperazin-1-yl]-5-oxopentanoic acid Show/Hide	C34H45N7O9	1
1	Ki = 80 nM Bioactivity Info	TI LI LO TS
CP0517539 Compound Info	(4S)-4-(4-(1-(diethylamino)-1-oxobutan-2-yloxy)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C32H43N5O8	1
1	Ki = 81 nM Bioactivity Info	TI LI LO TS
CP0482445 Compound Info	(4S)-5-[3-(butoxycarbonylamino)pyrrolidin-1-yl]-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C35H47N7O9	1
1	Ki = 82 nM Bioactivity Info	TI LI LO TS
CP0261352 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[4-(1-ethoxy-2-methyl-1-oxopropan-2-yl)oxy-7-methylquinoline-2-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C29H38N4O9	1
1	Ki = 86 nM Bioactivity Info	TI LI LO TS
CP0383992 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-[({4-[(2-hydroxyethyl)methyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C27H35N5O7	1
1	Ki = 87 nM Bioactivity Info	TI LI LO TS
CP0421652 Compound Info	(4S)4-{[(4-Butoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(hexyloxy)carbonyl]piperazin-1-yl}-5-oxopentanoic Acid Show/Hide	C32H44N4O7	1
1	Ki = 89 nM Bioactivity Info	TI LI LO TS
CP0383995 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(2-methoxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C27H34N4O8	2
1	Ki = 92 nM Bioactivity Info	TI LI LO TS
2	Ki = 140 nM Bioactivity Info	TI LI LO TS
CP0506292 Compound Info	(S)-5-(4-(allyloxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(piperidin-4-yloxy)picolinamido)pentanoic acid Show/Hide	C30H37N5O7	1
1	Ki = 93 nM Bioactivity Info	TI LI LO TS
CP0477670 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(2,2,2-trifluoroethoxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C24H25F3N4O6	1
1	Ki = 94 nM Bioactivity Info	TI LI LO TS
CP0477671 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-ethoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C26H32N4O7	1
1	Ki = 94 nM Bioactivity Info	TI LI LO TS
CP0502251 Compound Info	(S)-5-(4-(allyloxycarbonyl)piperazin-1-yl)-4-(4-(2-methoxyethoxy)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C28H34N4O8	1
1	Ki = 95 nM Bioactivity Info	TI LI LO TS
CP0383994 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-methoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid Show/Hide	C25H30N4O7	1
1	Ki = 96 nM Bioactivity Info	TI LI LO TS
CP0492622 Compound Info	(S)-5-(4-(allyloxycarbonyl)piperazin-1-yl)-4-(4-butoxy-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C29H36N4O7	1
1	Ki = 99 nM Bioactivity Info	TI LI LO TS
CP0506293 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-[({4-[(2-methoxyethyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C27H35N5O7	1
1	Ki = 99 nM Bioactivity Info	TI LI LO TS
CP0376804 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclopropylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C32H41N7O9	1
1	Ki = 105 nM Bioactivity Info	TI LI LO TS
CP0527186 Compound Info	ethyl 4-[2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]acetyl]piperazine-1-carboxylate Show/Hide	C30H39N7O7	1
1	Ki = 107 nM Bioactivity Info	TI LI LO TS
CP0513074 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]propanoyl]piperazine-1-carboxylate Show/Hide	C31H41N7O7	1
1	Ki = 111 nM Bioactivity Info	TI LI LO TS
CP0470941 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-piperidin-1-ylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C29H37N5O6	1
1	Ki = 112 nM Bioactivity Info	TI LI LO TS
CP0481512 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-[({4-[(2-hydroxyethyl)amino]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid Show/Hide	C26H33N5O7	2
1	Ki = 114 nM Bioactivity Info	TI LI LO TS
2	Ki = 117 nM Bioactivity Info	TI LI LO TS
CP0520478 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-propoxypyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C27H34N4O7	1
1	Ki = 120 nM Bioactivity Info	TI LI LO TS
CP0441472 Compound Info	(4S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(6-(1-(diethylamino)-1-oxobutan-2-yloxy)-2-phenylpyrimidine-4-carboxamido)-5-oxopentanoic acid Show/Hide	C33H46N6O8	1
1	Ki = 123 nM Bioactivity Info	TI LI LO TS
CP0485777 Compound Info	naphthalen-1-yl 4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazine-1-carboxylate Show/Hide	C23H22N4O2S	1
1	Ki = 130 nM Bioactivity Info	TI LI LO TS
CP0413942 Compound Info	(4S)-5-(4-benzoylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C37H43N7O8	1
1	Ki = 130 nM Bioactivity Info	TI LI LO TS
CP0520479 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(4-hydroxybutoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C28H36N4O8	1
1	Ki = 132 nM Bioactivity Info	TI LI LO TS
CP0500086 Compound Info	(4S)-4-[[5-(1-ethoxycarbonylcyclobutyl)oxy-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C29H37N5O9	1
1	Ki = 139 nM Bioactivity Info	TI LI LO TS
CP0439269 Compound Info	(S)-4-(4-(2-hydroxyethoxy)-6-phenylpicolinamido)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C27H34N4O8	1
1	Ki = 145 nM Bioactivity Info	TI LI LO TS
CP0545721 Compound Info	(S)-4-(4-butoxy-6-phenylpicolinamido)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C29H38N4O7	1
1	Ki = 146 nM Bioactivity Info	TI LI LO TS
CP0492623 Compound Info	(S)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(piperidin-4-yloxy)picolinamido)pentanoic acid Show/Hide	C30H39N5O7	1
1	Ki = 157 nM Bioactivity Info	TI LI LO TS
CP0514342 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-4-({[4-(2-hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoicAcid Show/Hide	C26H32N4O8	1
1	Ki = 157 nM Bioactivity Info	TI LI LO TS
CP0374050 Compound Info	3-(3-(6-ethyl-4-(4-(3,3,3-trifluoropropanoyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C19H23F3N6O4S	2
1	Ki = 172 nM Bioactivity Info	TI LI LO TS
2	Ki = 177 nM Bioactivity Info	TI LI LO TS
CP0565819 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoyl]piperazine-1-carboxylate Show/Hide	C33H45N7O7	1
1	Ki = 172 nM Bioactivity Info	TI LI LO TS
CP0500039 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-(2-oxopyrrolidin-1-yl)ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid Show/Hide	C28H34N6O9	1
1	Ki = 173 nM Bioactivity Info	TI LI LO TS
CP0488002 Compound Info	ethyl 4-[(2S)-4-amino-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]butanoyl]piperazine-1-carboxylate Show/Hide	C32H44N8O7	1
1	Ki = 180 nM Bioactivity Info	TI LI LO TS
CP0507226 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-3-methylbutanoyl]piperazine-1-carboxylate Show/Hide	C33H45N7O7	1
1	Ki = 183 nM Bioactivity Info	TI LI LO TS
CP0506504 Compound Info	(S)-4-(4-(2-(diethylamino)ethoxy)-6-phenylpyrimidine-2-carboxamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid Show/Hide	C32H46N6O7	1
1	Ki = 184 nM Bioactivity Info	TI LI LO TS
CP0517540 Compound Info	(S)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-4-(4-(2-methoxyethoxy)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C28H36N4O8	1
1	Ki = 189 nM Bioactivity Info	TI LI LO TS
CP0389569 Compound Info	(S)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(piperidin-4-ylmethylamino)picolinamido)pentanoic acid Show/Hide	C30H40N6O6	1
1	Ki = 190 nM Bioactivity Info	TI LI LO TS
CP0383618 Compound Info	3-(3-(6-ethyl-4-(4-(2-(3-methoxyphenoxy)acetyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C25H30N6O6S	2
1	Ki = 191 nM Bioactivity Info	TI LI LO TS
2	Ki = 447 nM Bioactivity Info	TI LI LO TS
CP0523456 Compound Info	(4S)-5-[(1-butoxycarbonylpyrrolidin-3-yl)amino]-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C35H47N7O9	1
1	Ki = 193 nM Bioactivity Info	TI LI LO TS
CP0536748 Compound Info	(4S)5-{4-[(Benzyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C29H30N4O6	1
1	Ki = 196 nM Bioactivity Info	TI LI LO TS
CP0452747 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-6-hydroxyhexanoyl]piperazine-1-carboxylate Show/Hide	C34H47N7O8	1
1	Ki = 202 nM Bioactivity Info	TI LI LO TS
CP0534825 Compound Info	(S)-5-(4-(allyloxycarbonyl)piperazin-1-yl)-4-(4-(2-hydroxyethoxy)-6-phenylpicolinamido)-5-oxopentanoic acid Show/Hide	C27H32N4O8	1
1	Ki = 203 nM Bioactivity Info	TI LI LO TS
CP0565818 Compound Info	ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-4-methylpentanoyl]piperazine-1-carboxylate Show/Hide	C34H47N7O7	1
1	Ki = 207 nM Bioactivity Info	TI LI LO TS
CP0389581 Compound Info	(S)-5-oxo-4-(6-phenylpicolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid Show/Hide	C24H28N4O6	1
1	Ki = 209 nM Bioactivity Info	TI LI LO TS
CP0520480 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoicAcid Show/Hide	C24H28N4O6	1
1	Ki = 209 nM Bioactivity Info	TI LI LO TS
CP0447580 Compound Info	3-(3-(6-ethyl-4-(4-(3-phenoxypropanoyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C25H30N6O5S	2
1	Ki = 213 nM Bioactivity Info	TI LI LO TS
2	Ki = 783 nM Bioactivity Info	TI LI LO TS
CP0492670 Compound Info	(S)-4-(4-(3-aminopropoxy)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C27H35N5O7	1
1	Ki = 214 nM Bioactivity Info	TI LI LO TS
CP0507229 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid Show/Hide	C33H43N7O9	1
1	Ki = 219 nM Bioactivity Info	TI LI LO TS
CP0498740 Compound Info	3-(3-(6-ethyl-4-(4-(2-phenylacetyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C24H28N6O4S	2
1	Ki = 223 nM Bioactivity Info	TI LI LO TS
2	Ki = 231 nM Bioactivity Info	TI LI LO TS
CP0544459 Compound Info	(4S)-4-[[5-[2-[3-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C33H43N7O9	1
1	Ki = 238 nM Bioactivity Info	TI LI LO TS
CP0401571 Compound Info	(4-(2-(4-aminopiperidin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)(biphenyl-4-yl)methanone Show/Hide	C30H34N6OS	2
1	Ki = 240 nM Bioactivity Info	TI LI LO TS
2	Ki = 325 nM Bioactivity Info	TI LI LO TS
CP0413947 Compound Info	(4S)-4-[[5-(3,3-dimethyl-2-oxobutoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C28H37N5O8	1
1	Ki = 242 nM Bioactivity Info	TI LI LO TS
CP0544461 Compound Info	(4S)-4-[[5-(2-cyclopropyl-2-oxoethoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C27H33N5O8	1
1	Ki = 249 nM Bioactivity Info	TI LI LO TS
CP0509310 Compound Info	(S)-4-(4-(2-(dimethylamino)ethylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid Show/Hide	C28H38N6O6	1
1	Ki = 270 nM Bioactivity Info	TI LI LO TS
CP0526316 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-{4-[(propylamino)carbonyl]piperazin-1-yl}pentanoic acid Show/Hide	C29H39N5O5	1
1	Ki = 277 nM Bioactivity Info	TI LI LO TS
CP0383996 Compound Info	(4S)5-[4-(Isopropoxycarbonyl)iperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C25H30N4O6	1
1	Ki = 280 nM Bioactivity Info	TI LI LO TS
CP0544460 Compound Info	(4S)-4-[[5-[2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C29H37N7O9	1
1	Ki = 283 nM Bioactivity Info	TI LI LO TS
CP0541366 Compound Info	(4S)5-{4-[(Ethylamino)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C28H37N5O5	1
1	Ki = 288 nM Bioactivity Info	TI LI LO TS
CP0485325 Compound Info	3-(3-(6-ethyl-4-(4-propionylpiperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C19H26N6O4S	2
1	Ki = 295 nM Bioactivity Info	TI LI LO TS
2	Ki = 367 nM Bioactivity Info	TI LI LO TS
CP0525479 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C31H41N7O9	1
1	Ki = 303 nM Bioactivity Info	TI LI LO TS
CP0470942 Compound Info	(4S)4-({[4-(2-Aminoethoxy)6-phenylpyridin-2-yl]carbonyl}-amino)5-[4-(ethoxycarbonyl)iperazin-1-yl]-5-oxopentanoicAcid Show/Hide	C26H33N5O7	1
1	Ki = 328 nM Bioactivity Info	TI LI LO TS
CP0389582 Compound Info	(S)-5-oxo-4-(2-phenylpyrimidine-4-carboxamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid Show/Hide	C23H27N5O6	1
1	Ki = 356 nM Bioactivity Info	TI LI LO TS
CP0482447 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-(2-ethoxy-2-oxoethoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C26H33N5O9	1
1	Ki = 372 nM Bioactivity Info	TI LI LO TS
CP0534827 Compound Info	(S)-5-Oxo-5-(4-propionyloxy-piperazin-1-yl)-4-[([1,1';3',1'']terphenyl-5'-carbonyl)-amino]-pentanoic acid Show/Hide	C31H33N3O6	1
1	Ki = 373 nM Bioactivity Info	TI LI LO TS
CP0421653 Compound Info	(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-[(1,1':3',1''-terphenyl-5'-ylcarbonyl)mino]pentanoic Acid Show/Hide	C31H33N3O6	1
1	Ki = 373 nM Bioactivity Info	TI LI LO TS
CP0473902 Compound Info	3-(3-(4-(4-acetylpiperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C18H24N6O4S	2
1	Ki = 380 nM Bioactivity Info	TI LI LO TS
2	Ki = 460 nM Bioactivity Info	TI LI LO TS
CP0374053 Compound Info	[4-(6-ethyl-2-piperazin-1-ylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]-(4-phenylphenyl)methanone Show/Hide	C29H32N6OS	2
1	Ki = 397 nM Bioactivity Info	TI LI LO TS
2	Ki = 410 nM Bioactivity Info	TI LI LO TS
CP0504265 Compound Info	(S)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenyl-4-(tetrahydro-2H-pyran-4-ylamino)picolinamido)pentanoic acid Show/Hide	C29H37N5O7	1
1	Ki = 455 nM Bioactivity Info	TI LI LO TS
CP0376806 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(3R)-3-hydroxypyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C28H36N6O9	1
1	Ki = 459 nM Bioactivity Info	TI LI LO TS
CP0508043 Compound Info	(S)-4-(2,6-diphenylisonicotinamido)-5-oxo-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid Show/Hide	C30H32N4O6	1
1	Ki = 484 nM Bioactivity Info	TI LI LO TS
CP0507710 Compound Info	(4S)-4-[(2,6-Diphenylisonicotinoyl)amino]-5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C30H32N4O6	1
1	Ki = 484 nM Bioactivity Info	TI LI LO TS
CP0514343 Compound Info	(4S)5-{4-[(2-Methoxyethoxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C25H30N4O7	1
1	Ki = 492 nM Bioactivity Info	TI LI LO TS
CP0534171 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(methylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C30H39N7O9	1
1	Ki = 536 nM Bioactivity Info	TI LI LO TS
CP0463925 Compound Info	3-(3-(6-ethyl-4-(4-(2-phenoxyacetyl)piperazin-1-yl)thieno[2,3-d]pyrimidin-2-yl)ureido)propanoic acid Show/Hide	C24H28N6O5S	2
1	Ki = 539 nM Bioactivity Info	TI LI LO TS
2	Ki = 593 nM Bioactivity Info	TI LI LO TS
CP0482446 Compound Info	(4S)-4-[[5-(2-cyclobutyl-2-oxoethoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C28H35N5O8	1
1	Ki = 574 nM Bioactivity Info	TI LI LO TS
CP0499359 Compound Info	(4S)5-{4-[(Butylamino)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C30H41N5O5	1
1	Ki = 613 nM Bioactivity Info	TI LI LO TS
CP0513080 Compound Info	(4S)-4-[[5-[2-[3-(cyclobutylcarbamoyl)azetidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C32H41N7O9	1
1	Ki = 613 nM Bioactivity Info	TI LI LO TS
CP0485324 Compound Info	1-(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)-2-phenylethanone Show/Hide	C20H22N4OS	1
1	Ki = 660 nM Bioactivity Info	TI LI LO TS
CP0534828 Compound Info	4-(2-(4,6-diphenylpicolinamido)acetyl)piperazin-1-yl propionate Show/Hide	C27H28N4O4	1
1	Ki = 733 nM Bioactivity Info	TI LI LO TS
CP0514344 Compound Info	ethyl 4-[2-[(4,6-diphenylpyridine-2-carbonyl)amino]acetyl]piperazine-1-carboxylate Show/Hide	C27H28N4O4	1
1	Ki = 733 nM Bioactivity Info	TI LI LO TS
CP0447581 Compound Info	1-(4-(4-(4-(biphenylcarbonyl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyrimidin-2-yl)piperazin-1-yl)-2,2,2-trifluoroethanone Show/Hide	C31H31F3N6O2S	2
1	Ki = 839 nM Bioactivity Info	TI LI LO TS
2	Ki = 1810 nM Bioactivity Info	TI LI LO TS
CP0447513 Compound Info	(4S)5-[4-(Anilinocarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C32H37N5O5	1
1	Ki = 842 nM Bioactivity Info	TI LI LO TS
CP0526317 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-[4-(phenylsulfonyl)piperazin-1-yl]pentanoic acid Show/Hide	C31H36N4O6S	1
1	Ki = 842 nM Bioactivity Info	TI LI LO TS
CP0534170 Compound Info	(4S)-4-[[5-[2-[(2R)-2-(cyclopropylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C32H41N7O9	1
1	Ki = 958 nM Bioactivity Info	TI LI LO TS
CP0534829 Compound Info	(S)-5-oxo-4-(4-phenylpyrimidine-2-carboxamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid Show/Hide	C23H27N5O6	1
1	Ki = 1190 nM Bioactivity Info	TI LI LO TS
CP0513938 Compound Info	(S)Ethyl 4-{4-Carboxy-2-[(4-phenylpyrimidine-2-carbonyl)amino]butyryl}piperazine-1-carboxylate Show/Hide	C23H27N5O6	1
1	Ki = 1190 nM Bioactivity Info	TI LI LO TS
CP0506338 Compound Info	(4S)4-[(1,1'-Biphenyl-3-ylcarbonyl)mino]-5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C29H31N3O4	1
1	Ki = 1310 nM Bioactivity Info	TI LI LO TS
CP0506339 Compound Info	(4S)5-[4-(3-Methylphenyl)piperazin-1-yl]-5-oxo-4-[(1,1':3',1''-terphenyl-5'-ylcarbonyl)amino]pentanoic Acid Show/Hide	C35H35N3O4	1
1	Ki = 1430 nM Bioactivity Info	TI LI LO TS
CP0536487 Compound Info	(4S)5-Oxo-5-(4-pentanoylpiperazin-1-yl)4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C30H40N4O5	1
1	Ki = 1430 nM Bioactivity Info	TI LI LO TS
CP0439259 Compound Info	4-(2-(6-phenylpicolinamido)acetyl)piperazin-1-yl propionate Show/Hide	C21H24N4O4	1
1	Ki = 1610 nM Bioactivity Info	TI LI LO TS
CP0507711 Compound Info	ethyl 4-[2-[(6-phenylpyridine-2-carbonyl)amino]acetyl]piperazine-1-carboxylate Show/Hide	C21H24N4O4	1
1	Ki = 1610 nM Bioactivity Info	TI LI LO TS
CP0541367 Compound Info	(4S)5-(4-Benzoylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C32H36N4O5	1
1	Ki = 1880 nM Bioactivity Info	TI LI LO TS
CP0494312 Compound Info	1-(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)-3-methylbutan-1-one Show/Hide	C17H24N4OS	1
1	Ki = 2100 nM Bioactivity Info	TI LI LO TS
CP0508044 Compound Info	(4S)5-[4-(Methoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C23H26N4O6	1
1	Ki = 2440 nM Bioactivity Info	TI LI LO TS
CP0452750 Compound Info	(4S)-4-[[5-(2-amino-2-oxoethoxy)-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C24H30N6O8	1
1	Ki = 2720 nM Bioactivity Info	TI LI LO TS
CP0447586 Compound Info	1-(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)-3,3,3-trifluoropropan-1-one Show/Hide	C15H17F3N4OS	1
1	Ki = 2990 nM Bioactivity Info	TI LI LO TS
CP0502645 Compound Info	(4S)5-(4-Butyrylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C29H38N4O5	1
1	Ki = 3100 nM Bioactivity Info	TI LI LO TS
CP0534830 Compound Info	(S)-4-biphenyl-3-ylcarboxamido-5-oxo-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid Show/Hide	C25H29N3O6	1
1	Ki = 3640 nM Bioactivity Info	TI LI LO TS
CP0383999 Compound Info	(4S)4-[(1,10-Biphenyl-3-ylcarbonyl)mino]-5-[4-(ethoxycarbonyl)piperazin-1-yl]-5-oxopentanoic Acid Show/Hide	C25H29N3O6	1
1	Ki = 3640 nM Bioactivity Info	TI LI LO TS
CP0188030 Compound Info	(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)(phenyl)methanone Show/Hide	C19H20N4OS	1
1	Ki = 4400 nM Bioactivity Info	TI LI LO TS
CP0537812 Compound Info	(4S)5-(4-Hexylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C31H44N4O4	1
1	Ki > 2710 nM Bioactivity Info	TI LI LO TS
CP0383773 Compound Info	(4S)5-(4-Isobutyrylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C29H38N4O5	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0469879 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-(4-propionylpiperazin-1-yl)pentanoic acid Show/Hide	C28H36N4O5	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0501498 Compound Info	(4S)5-[4-(Butylsulfonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C29H40N4O6S	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0518792 Compound Info	(4S)5-[4-(N,N-Dimethylglycyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C29H39N5O5	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0518793 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-[4-(propylsulfonyl)piperazin-1-yl]pentanoic acid Show/Hide	C28H38N4O6S	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0527153 Compound Info	(4S)5-[4-(Ethylsulfonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C27H36N4O6S	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0537763 Compound Info	(4S)5-Oxo-5-(4-pentylpiperazin-1-yl)4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C30H42N4O4	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0537764 Compound Info	(4S)5-(4-Acetylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C27H34N4O5	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0537765 Compound Info	(4S)5-[4-(Methoxyacetyl)iperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C28H36N4O6	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0537766 Compound Info	(4S)5-Oxo-5-[4-(pentylsulfonyl)piperazin-1-yl]-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C30H42N4O6S	1
1	Ki > 3590 nM Bioactivity Info	TI LI LO TS
CP0469880 Compound Info	(4S)5-(4-Isobutylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid Show/Hide	C29H40N4O4	1
1	Ki > 3800 nM Bioactivity Info	TI LI LO TS
CP0502646 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-(4-propylpiperazin-1-yl)pentanoic acid Show/Hide	C28H38N4O4	1
1	Ki > 3800 nM Bioactivity Info	TI LI LO TS
CP0381620 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[(3-oxo-2-phenyl-1H-pyrazole-5-carbonyl)amino]pentanoic acid Show/Hide	C22H27N5O7	1
1	Ki > 5000 nM Bioactivity Info	TI LI LO TS
CP0452749 Compound Info	(4S)-4-[[5-[2-(diethylamino)-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid Show/Hide	C28H38N6O8	1
1	Ki > 5000 nM Bioactivity Info	TI LI LO TS
CP0480983 Compound Info	(4S)-4-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-[(1-ethoxycarbonylpiperidin-4-yl)amino]-5-oxopentanoic acid Show/Hide	C34H45N7O9	1
1	Ki > 5000 nM Bioactivity Info	TI LI LO TS
CP0504755 Compound Info	(S)-5-oxo-4-(picolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid Show/Hide	C18H24N4O6	1
1	Ki > 5400 nM Bioactivity Info	TI LI LO TS
CP0473493 Compound Info	(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-[(pyridin-2-ylcarbonyl)mino]pentanoic Acid Show/Hide	C18H24N4O6	1
1	Ki > 5400 nM Bioactivity Info	TI LI LO TS
CP0518794 Compound Info	(4S)5-Oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}-5-piperazin-1-ylpentanoate Show/Hide	C25H32N4O4	1
1	Ki > 5680 nM Bioactivity Info	TI LI LO TS
CP0389583 Compound Info	(S)-5-oxo-4-(4-phenylpicolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid Show/Hide	C24H28N4O6	1
1	Ki > 5700 nM Bioactivity Info	TI LI LO TS
CP0517542 Compound Info	(4S)5-[4-(3-Methylphenyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoicAcid Show/Hide	C28H30N4O4	1
1	Ki > 5700 nM Bioactivity Info	TI LI LO TS
CP0491180 Compound Info	(4S)5-[4-(3-Methylphenyl)piperazin-1-yl]-5-oxo-4-{[(4-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C28H30N4O4	1
1	Ki > 5700 nM Bioactivity Info	TI LI LO TS
CP0497019 Compound Info	(42S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(4-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid Show/Hide	C24H28N4O6	1
1	Ki > 5700 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000006 , HEK293

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0140474 Compound Info	AR-C126532XX Show/Hide	C23H28F2N6O4S	2
1	IC50 = 5.012 nM
2	IC50 = 10 nM
CP0540055 Compound Info	N-[6-(4-butanoyl-5-methylpyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]indole-3-carboxamide Show/Hide	C28H31ClN8O3	1
1	IC50 = 17 nM
CP0261352 Compound Info	(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[4-(1-ethoxy-2-methyl-1-oxopropan-2-yl)oxy-7-methylquinoline-2-carbonyl]amino]-5-oxopentanoic acid Show/Hide	C29H38N4O9	1
1	IC50 = 29 nM
CP0534172 Compound Info	ELINOGREL Show/Hide	C20H15ClFN5O5S2	2
1	IC50 = 50 nM
2	Ki = 23 nM
CP0140475 Compound Info	ethyl 6-[3-[(5-chlorothiophen-2-yl)sulfonylcarbamoyl]azetidin-1-yl]-5-cyano-2-methylpyridine-3-carboxylate Show/Hide	C18H17ClN4O5S2	2
1	IC50 = 60 nM
2	IC50 = 100 nM
CP0381097 Compound Info	(4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid Show/Hide	C34H47N5O7	1
1	Ki = 3.5 nM
CP0477009 Compound Info	butyl 4-[2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]acetyl]piperazine-1-carboxylate Show/Hide	C32H43N7O7	1
1	Ki = 7.7 nM
CP0851936 Compound Info	sodium 1-amino-9,10-dioxo-4-(4-(phenylamino)-3-sulfonatophenylamino)-9,10-dihydroanthracene-2-sulfonate Show/Hide	C26H17N3Na2O8S2	1
1	Ki = 25 nM

Clinical Information about the Protein

Target 1 ( P2Y purinoceptor 12 (P2RY12) )

Target Type	Successful Target
Disease	4 Target-related Diseases				4
1	Thrombosis [ICD-11: DB61-GB90]
2	Acute coronary syndrome [ICD-11: BA41]
3	Cardiovascular disease [ICD-11: BA00-BE2Z]
4	Myocardial infarction [ICD-11: BA41-BA43]
Approved Drug(s)	4 Approved Drugs				4
1	Cangrelor	Drug Info	Approved	Thrombosis
2	Clopidogrel	Drug Info	Approved	Thrombosis
3	Prasugrel	Drug Info	Approved	Acute coronary syndrome
4	Brilinta	Drug Info	Approved	Thrombosis
Clinical Trial Drug(s)	3 Clinical Trial Drugs				3
1	INS-50589	Drug Info	Phase 2	Cardiovascular disease
2	ARL-67085	Drug Info	Phase 1	Thrombosis
3	Elinogrel	Drug Info	Phase 1	Myocardial infarction

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