General Information of the Compound
Compound ID
CP0508101
Compound Name
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[6-[[(3R)-oxolan-3-yl]amino]-2-phenylpyrimidine-4-carbonyl]amino]pentanoic acid
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Structure
Formula
C27H34N6O7
Molecular Weight
554.604
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(N[C@@H]2CCOC2)nc(n1)-c1ccccc1
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InChI
InChI=1S/C27H34N6O7/c1-2-40-27(38)33-13-11-32(12-14-33)26(37)20(8-9-23(34)35)30-25(36)21-16-22(28-19-10-15-39-17-19)31-24(29-21)18-6-4-3-5-7-18/h3-7,16,19-20H,2,8-15,17H2,1H3,(H,30,36)(H,34,35)(H,28,29,31)/t19-,20+/m1/s1
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InChIKey
TUFDACIRTOGMHR-UXHICEINSA-N
Physicochemical Property
logP
1.6083
Rotatable Bonds
10
Heavy Atom Count
40
Polar Areas
163.29
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
9
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 67460268
ChEMBL ID
CHEMBL3322643
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 25 nM
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