General Information of the Compound
Compound ID
CP0452747
Compound Name
ethyl 4-[(2S)-2-[[5-[2-[(2S)-2-(cyclobutylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-6-hydroxyhexanoyl]piperazine-1-carboxylate
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Structure
Formula
C34H47N7O8
Molecular Weight
681.791
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCCCO)NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(n1)-c1ccccc1
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InChI
InChI=1S/C34H47N7O8/c1-2-48-34(47)39-19-17-38(18-20-39)33(46)26(14-6-7-21-42)36-31(44)27-22-30(41(37-27)25-12-4-3-5-13-25)49-23-29(43)40-16-9-15-28(40)32(45)35-24-10-8-11-24/h3-5,12-13,22,24,26,28,42H,2,6-11,14-21,23H2,1H3,(H,35,45)(H,36,44)/t26-,28-/m0/s1
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InChIKey
ODBAAHFXGCBHDI-XCZPVHLTSA-N
Physicochemical Property
logP
1.4725
Rotatable Bonds
14
Heavy Atom Count
49
Polar Areas
175.64
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
10
Complexity
49

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 66856952
SID: 163454784
ChEMBL ID
CHEMBL2172134
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 202 nM
   TI
   LI
   LO
   TS