General Information of the Compound
Compound ID
CP0536748
Compound Name
(4S)5-{4-[(Benzyloxy)carbonyl]piperazin-1-yl}-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
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Structure
Formula
C29H30N4O6
Molecular Weight
530.581
Canonical SMILES
OC(=O)CC[C@H](NC(=O)c1cccc(n1)-c1ccccc1)C(=O)N1CCN(CC1)C(=O)OCc1ccccc1
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InChI
InChI=1S/C29H30N4O6/c34-26(35)15-14-25(31-27(36)24-13-7-12-23(30-24)22-10-5-2-6-11-22)28(37)32-16-18-33(19-17-32)29(38)39-20-21-8-3-1-4-9-21/h1-13,25H,14-20H2,(H,31,36)(H,34,35)/t25-/m0/s1
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InChIKey
IBSLJRBNLBOEAO-VWLOTQADSA-N
Physicochemical Property
logP
3.1928
Rotatable Bonds
9
Heavy Atom Count
39
Polar Areas
129.14
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45140353
SID: 92390292
ChEMBL ID
CHEMBL597563
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 196 nM
   TI
   LI
   LO
   TS