General Information of the Compound
Compound ID
CP0501498
Compound Name
(4S)5-[4-(Butylsulfonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
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Structure
Formula
C29H40N4O6S
Molecular Weight
572.728
Canonical SMILES
CCCCS(=O)(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c1cccc(n1)-c1ccccc1
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InChI
InChI=1S/C29H40N4O6S/c1-5-6-21-40(37,38)33-19-17-32(18-20-33)28(36)25(15-16-26(34)39-29(2,3)4)31-27(35)24-14-10-13-23(30-24)22-11-8-7-9-12-22/h7-14,25H,5-6,15-21H2,1-4H3,(H,31,35)/t25-/m0/s1
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InChIKey
JPFHFKTWFOCMIK-VWLOTQADSA-N
Physicochemical Property
logP
3.243
Rotatable Bonds
11
Heavy Atom Count
40
Polar Areas
125.98
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46233093
ChEMBL ID
CHEMBL599991
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 3590 nM
   TI
   LI
   LO
   TS