General Information of the Compound
Compound ID
CP0477671
Compound Name
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-4-{[(4-ethoxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
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Structure
Formula
C26H32N4O7
Molecular Weight
512.563
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OCC)cc(n1)-c1ccccc1
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InChI
InChI=1S/C26H32N4O7/c1-3-36-19-16-21(18-8-6-5-7-9-18)27-22(17-19)24(33)28-20(10-11-23(31)32)25(34)29-12-14-30(15-13-29)26(35)37-4-2/h5-9,16-17,20H,3-4,10-15H2,1-2H3,(H,28,33)(H,31,32)/t20-/m0/s1
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InChIKey
UNGIRSVYGZKGFN-FQEVSTJZSA-N
Physicochemical Property
logP
2.4112
Rotatable Bonds
10
Heavy Atom Count
37
Polar Areas
138.37
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45142447
SID: 92392438
ChEMBL ID
CHEMBL598177
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 94 nM
   TI
   LI
   LO
   TS