General Information of the Compound
Compound ID
CP0375518
Compound Name
(4S)4-{[(4-{[(2-Methoxyethoxy)carbonyl]amino}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
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Structure
Formula
C35H49N5O9
Molecular Weight
683.803
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c1cc(NC(=O)OCCOC)cc(n1)-c1ccccc1
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InChI
InChI=1S/C35H49N5O9/c1-6-7-11-20-48-34(45)40-18-16-39(17-19-40)32(43)27(14-15-30(41)49-35(2,3)4)38-31(42)29-24-26(36-33(44)47-22-21-46-5)23-28(37-29)25-12-9-8-10-13-25/h8-10,12-13,23-24,27H,6-7,11,14-22H2,1-5H3,(H,38,42)(H,36,37,44)/t27-/m0/s1
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InChIKey
YMFPCZLGSOEPJQ-MHZLTWQESA-N
Physicochemical Property
logP
4.6348
Rotatable Bonds
15
Heavy Atom Count
49
Polar Areas
165.7
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
10
Complexity
49

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46233241
ChEMBL ID
CHEMBL578094
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS