General Information of the Compound
Compound ID
CP0526321
Compound Name
(4S)5-{4-[(Hexyloxy)carbonyl]piperazin-1-yl}-4-{[(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxopentanoic Acid
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Structure
Formula
C28H36N4O7
Molecular Weight
540.617
Canonical SMILES
CCCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(O)cc(n1)-c1ccccc1
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InChI
InChI=1S/C28H36N4O7/c1-2-3-4-8-17-39-28(38)32-15-13-31(14-16-32)27(37)22(11-12-25(34)35)30-26(36)24-19-21(33)18-23(29-24)20-9-6-5-7-10-20/h5-7,9-10,18-19,22H,2-4,8,11-17H2,1H3,(H,29,33)(H,30,36)(H,34,35)/t22-/m0/s1
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InChIKey
HSNHMFXWJDPWHN-QFIPXVFZSA-N
Physicochemical Property
logP
3.2785
Rotatable Bonds
12
Heavy Atom Count
39
Polar Areas
149.37
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45140160
SID: 92390103
ChEMBL ID
CHEMBL599005
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 20 nM
   TI
   LI
   LO
   TS