General Information of the Compound
Compound ID
CP0507679
Compound Name
(4S)-4-[({4-[3-(Dimethylamino)-3-oxopropyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
    Show/Hide
Structure
Formula
C32H43N5O7
Molecular Weight
609.724
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(CCC(=O)N(C)C)cc(n1)-c1ccccc1
    Show/Hide
InChI
InChI=1S/C32H43N5O7/c1-4-5-9-20-44-32(43)37-18-16-36(17-19-37)31(42)25(13-15-29(39)40)34-30(41)27-22-23(12-14-28(38)35(2)3)21-26(33-27)24-10-7-6-8-11-24/h6-8,10-11,21-22,25H,4-5,9,12-20H2,1-3H3,(H,34,41)(H,39,40)/t25-/m0/s1
    Show/Hide
InChIKey
SIQJDUMTBGBKHP-VWLOTQADSA-N
Physicochemical Property
logP
3.2036
Rotatable Bonds
14
Heavy Atom Count
44
Polar Areas
149.45
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
44

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 45140938
SID: 92390888
ChEMBL ID
CHEMBL591048
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2.1 nM
   TI
   LI
   LO
   TS