General Information of the Compound
Compound ID
CP0383880
Compound Name
(4S)-4-({[4-(4-Hydroxybutyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
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Structure
Formula
C31H42N4O7
Molecular Weight
582.698
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(CCCCO)cc(n1)-c1ccccc1
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InChI
InChI=1S/C31H42N4O7/c1-2-3-9-20-42-31(41)35-17-15-34(16-18-35)30(40)25(13-14-28(37)38)33-29(39)27-22-23(10-7-8-19-36)21-26(32-27)24-11-5-4-6-12-24/h4-6,11-12,21-22,25,36H,2-3,7-10,13-20H2,1H3,(H,33,39)(H,37,38)/t25-/m0/s1
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InChIKey
DALIHPSDSJCUCB-VWLOTQADSA-N
Physicochemical Property
logP
3.4978
Rotatable Bonds
15
Heavy Atom Count
42
Polar Areas
149.37
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45140557
SID: 92390501
ChEMBL ID
CHEMBL590798
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.6 nM
   TI
   LI
   LO
   TS