General Information of the Compound
Compound ID
CP0519066
Compound Name
(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-{[(6-phenyl-4-{[1-(trifluoroacetyl)iperidin-4-yl]methoxy}pyridin-2-yl)carbonyl]-amino}pentanoic Acid
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Structure
Formula
C34H42F3N5O8
Molecular Weight
705.731
Canonical SMILES
CCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OCC2CCN(CC2)C(=O)C(F)(F)F)cc(n1)-c1ccccc1
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InChI
InChI=1S/C34H42F3N5O8/c1-2-3-19-49-33(48)42-17-15-40(16-18-42)31(46)26(9-10-29(43)44)39-30(45)28-21-25(20-27(38-28)24-7-5-4-6-8-24)50-22-23-11-13-41(14-12-23)32(47)34(35,36)37/h4-8,20-21,23,26H,2-3,9-19,22H2,1H3,(H,39,45)(H,43,44)/t26-/m0/s1
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InChIKey
LVAUCBGHSJHZGJ-SANMLTNESA-N
Physicochemical Property
logP
3.9724
Rotatable Bonds
13
Heavy Atom Count
50
Polar Areas
158.68
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
50

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45142222
SID: 92392210
ChEMBL ID
CHEMBL600370
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 10 nM
   TI
   LI
   LO
   TS