General Information of the Compound
Compound ID
CP0481518
Compound Name
(4S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(4-pyrrolidin-1-ylpiperidin-1-yl)pyridin-2-yl]carbonyl}amino)pentanoic Acid
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Structure
Formula
C33H44N6O6
Molecular Weight
620.751
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CCC(CC1)N1CCCC1
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InChI
InChI=1S/C33H44N6O6/c1-2-45-33(44)39-20-18-38(19-21-39)32(43)27(10-11-30(40)41)35-31(42)29-23-26(22-28(34-29)24-8-4-3-5-9-24)37-16-12-25(13-17-37)36-14-6-7-15-36/h3-5,8-9,22-23,25,27H,2,6-7,10-21H2,1H3,(H,35,42)(H,40,41)/t27-/m0/s1
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InChIKey
TYSPZJVREGKCIO-MHZLTWQESA-N
Physicochemical Property
logP
3.0771
Rotatable Bonds
10
Heavy Atom Count
45
Polar Areas
135.62
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45272055
ChEMBL ID
CHEMBL540737
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 34 nM
   TI
   LI
   LO
   TS