General Information of the Compound
Compound ID
CP0513930
Compound Name
(4S)-4-[({4-[3-(Diethylamino)propyl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
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Structure
Formula
C34H49N5O6
Molecular Weight
623.795
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(CCCN(CC)CC)cc(n1)-c1ccccc1
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InChI
InChI=1S/C34H49N5O6/c1-4-7-11-23-45-34(44)39-21-19-38(20-22-39)33(43)28(16-17-31(40)41)36-32(42)30-25-26(13-12-18-37(5-2)6-3)24-29(35-30)27-14-9-8-10-15-27/h8-10,14-15,24-25,28H,4-7,11-13,16-23H2,1-3H3,(H,36,42)(H,40,41)/t28-/m0/s1
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InChIKey
DQZCBQNACFOUEL-NDEPHWFRSA-N
Physicochemical Property
logP
4.4572
Rotatable Bonds
17
Heavy Atom Count
45
Polar Areas
132.38
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45140936
SID: 92390886
ChEMBL ID
CHEMBL591226
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 22 nM
   TI
   LI
   LO
   TS