General Information of the Compound
Compound ID
CP0507229
Compound Name
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxo-4-[[5-[2-oxo-2-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]ethoxy]-1-phenylpyrazole-3-carbonyl]amino]pentanoic acid
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Structure
Formula
C33H43N7O9
Molecular Weight
681.747
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)N2CCCC2)n(n1)-c1ccccc1
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InChI
InChI=1S/C33H43N7O9/c1-2-48-33(47)38-19-17-37(18-20-38)31(45)24(12-13-29(42)43)34-30(44)25-21-28(40(35-25)23-9-4-3-5-10-23)49-22-27(41)39-16-8-11-26(39)32(46)36-14-6-7-15-36/h3-5,9-10,21,24,26H,2,6-8,11-20,22H2,1H3,(H,34,44)(H,42,43)/t24-,26-/m0/s1
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InChIKey
KFUNMCRSFZOQBO-AHWVRZQESA-N
Physicochemical Property
logP
1.1284
Rotatable Bonds
12
Heavy Atom Count
49
Polar Areas
183.92
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
10
Complexity
49

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44129522
SID: 84981562
ChEMBL ID
CHEMBL2172160
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 219 nM
   TI
   LI
   LO
   TS