General Information of the Compound
Compound ID
CP0520410
Compound Name
(4S)-4-({[4-(Aminocarbonyl)-6-phenylpyridin-2-yl]carbonyl}-amino)-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoicAcid
    Show/Hide
Structure
Formula
C28H35N5O7
Molecular Weight
553.616
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)C(N)=O
    Show/Hide
InChI
InChI=1S/C28H35N5O7/c1-2-3-7-16-40-28(39)33-14-12-32(13-15-33)27(38)21(10-11-24(34)35)31-26(37)23-18-20(25(29)36)17-22(30-23)19-8-5-4-6-9-19/h4-6,8-9,17-18,21H,2-3,7,10-16H2,1H3,(H2,29,36)(H,31,37)(H,34,35)/t21-/m0/s1
    Show/Hide
InChIKey
RDTKCAPVFLBVCJ-NRFANRHFSA-N
Physicochemical Property
logP
2.2817
Rotatable Bonds
12
Heavy Atom Count
40
Polar Areas
172.23
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 45139591
SID: 92389489
ChEMBL ID
CHEMBL598160
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 7.5 nM
   TI
   LI
   LO
   TS