General Information of the Compound
Compound ID
CP0383763
Compound Name
(4S)4-[({4-[(N,N-Dimethylglycyl)mino]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic acid
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Structure
Formula
C35H50N6O7
Molecular Weight
666.82
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c1cc(NC(=O)CN(C)C)cc(n1)-c1ccccc1
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InChI
InChI=1S/C35H50N6O7/c1-7-8-12-21-47-34(46)41-19-17-40(18-20-41)33(45)27(15-16-31(43)48-35(2,3)4)38-32(44)29-23-26(36-30(42)24-39(5)6)22-28(37-29)25-13-10-9-11-14-25/h9-11,13-14,22-23,27H,7-8,12,15-21,24H2,1-6H3,(H,38,44)(H,36,37,42)/t27-/m0/s1
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InChIKey
ANKCAPALFVNBKG-MHZLTWQESA-N
Physicochemical Property
logP
3.94
Rotatable Bonds
14
Heavy Atom Count
48
Polar Areas
150.48
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
48

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46233232
ChEMBL ID
CHEMBL578482
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 4.1 nM
   TI
   LI
   LO
   TS