General Information of the Compound
Compound ID
CP0545721
Compound Name
(S)-4-(4-butoxy-6-phenylpicolinamido)-5-(4-(isopropoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
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Structure
Formula
C29H38N4O7
Molecular Weight
554.644
Canonical SMILES
CCCCOc1cc(nc(c1)-c1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCN(CC1)C(=O)OC(C)C
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InChI
InChI=1S/C29H38N4O7/c1-4-5-17-39-22-18-24(21-9-7-6-8-10-21)30-25(19-22)27(36)31-23(11-12-26(34)35)28(37)32-13-15-33(16-14-32)29(38)40-20(2)3/h6-10,18-20,23H,4-5,11-17H2,1-3H3,(H,31,36)(H,34,35)/t23-/m0/s1
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InChIKey
IPLVEOARTMHRQJ-QHCPKHFHSA-N
Physicochemical Property
logP
3.5799
Rotatable Bonds
12
Heavy Atom Count
40
Polar Areas
138.37
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45270318
ChEMBL ID
CHEMBL550415
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 146 nM
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   LI
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