General Information of the Compound
Compound ID
CP0507731
Compound Name
(S)-4-(4-(3-morpholinoazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
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Structure
Formula
C34H46N6O7
Molecular Weight
650.777
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CC(C1)N1CCOCC1
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InChI
InChI=1S/C34H46N6O7/c1-2-3-7-18-47-34(45)39-14-12-38(13-15-39)33(44)28(10-11-31(41)42)36-32(43)30-22-26(21-29(35-30)25-8-5-4-6-9-25)40-23-27(24-40)37-16-19-46-20-17-37/h4-6,8-9,21-22,27-28H,2-3,7,10-20,23-24H2,1H3,(H,36,43)(H,41,42)/t28-/m0/s1
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InChIKey
SAHWNZLCCJXNFR-NDEPHWFRSA-N
Physicochemical Property
logP
2.7036
Rotatable Bonds
13
Heavy Atom Count
47
Polar Areas
144.85
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
47

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46232947
ChEMBL ID
CHEMBL601487
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.3 nM
   TI
   LI
   LO
   TS