General Information of the Compound
Compound ID
CP0401974
Compound Name
(S)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)-4-(6-phenyl-4-(4-propylpiperazin-1-yl)picolinamido)pentanoic acid
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Structure
Formula
C34H48N6O6
Molecular Weight
636.794
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CCN(CCC)CC1
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InChI
InChI=1S/C34H48N6O6/c1-3-5-9-23-46-34(45)40-21-19-39(20-22-40)33(44)28(12-13-31(41)42)36-32(43)30-25-27(38-17-15-37(14-4-2)16-18-38)24-29(35-30)26-10-7-6-8-11-26/h6-8,10-11,24-25,28H,3-5,9,12-23H2,1-2H3,(H,36,43)(H,41,42)/t28-/m0/s1
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InChIKey
DAHNSCDTKJRDMZ-NDEPHWFRSA-N
Physicochemical Property
logP
3.7148
Rotatable Bonds
14
Heavy Atom Count
46
Polar Areas
135.62
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
46

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46232903
ChEMBL ID
CHEMBL590006
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 29 nM
   TI
   LI
   LO
   TS