General Information of the Compound
Compound ID
CP0517539
Compound Name
(4S)-4-(4-(1-(diethylamino)-1-oxobutan-2-yloxy)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
    Show/Hide
Structure
Formula
C32H43N5O8
Molecular Weight
625.723
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OC(CC)C(=O)N(CC)CC)cc(n1)-c1ccccc1
    Show/Hide
InChI
InChI=1S/C32H43N5O8/c1-5-27(31(42)35(6-2)7-3)45-23-20-25(22-12-10-9-11-13-22)33-26(21-23)29(40)34-24(14-15-28(38)39)30(41)36-16-18-37(19-17-36)32(43)44-8-4/h9-13,20-21,24,27H,5-8,14-19H2,1-4H3,(H,34,40)(H,38,39)/t24-,27?/m0/s1
    Show/Hide
InChIKey
UOFMHHLNQSQNBM-BXXZMZEQSA-N
Physicochemical Property
logP
3.0383
Rotatable Bonds
14
Heavy Atom Count
45
Polar Areas
158.68
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 45270295
ChEMBL ID
CHEMBL538171
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 81 nM
   TI
   LI
   LO
   TS