General Information of the Compound
Compound ID
CP0371902
Compound Name
(4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-5-oxo-4-({[6-phenyl-4-(pyrrolidin-3-yloxy)yridin-2-yl]carbonyl}amino)entanoic Acid
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Structure
Formula
C30H39N5O7
Molecular Weight
581.67
Canonical SMILES
CCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OC2CCNC2)cc(n1)-c1ccccc1
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InChI
InChI=1S/C30H39N5O7/c1-2-3-17-41-30(40)35-15-13-34(14-16-35)29(39)24(9-10-27(36)37)33-28(38)26-19-23(42-22-11-12-31-20-22)18-25(32-26)21-7-5-4-6-8-21/h4-8,18-19,22,24,31H,2-3,9-17,20H2,1H3,(H,33,38)(H,36,37)/t22?,24-/m0/s1
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InChIKey
VOYFORYMAZPQDL-GITCGBDTSA-N
Physicochemical Property
logP
2.5334
Rotatable Bonds
12
Heavy Atom Count
42
Polar Areas
150.4
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
8
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45139587
SID: 92389485
ChEMBL ID
CHEMBL592563
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.7 nM
   TI
   LI
   LO
   TS