General Information of the Compound
Compound ID
CP0485240
Compound Name
(S)-4-(4-(benzylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
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Structure
Formula
C31H35N5O6
Molecular Weight
573.65
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(NCc2ccccc2)cc(n1)-c1ccccc1
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InChI
InChI=1S/C31H35N5O6/c1-2-42-31(41)36-17-15-35(16-18-36)30(40)25(13-14-28(37)38)34-29(39)27-20-24(32-21-22-9-5-3-6-10-22)19-26(33-27)23-11-7-4-8-12-23/h3-12,19-20,25H,2,13-18,21H2,1H3,(H,32,33)(H,34,39)(H,37,38)/t25-/m0/s1
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InChIKey
ZLLQGEBQRDGKHV-VWLOTQADSA-N
Physicochemical Property
logP
3.6246
Rotatable Bonds
11
Heavy Atom Count
42
Polar Areas
141.17
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45268619
ChEMBL ID
CHEMBL553572
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 26 nM
   TI
   LI
   LO
   TS