General Information of the Compound
Compound ID
CP0400242
Compound Name
N-[4-(4-butanoyl-5-methylpyrazol-1-yl)phenyl]-1-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]-5-methylindole-3-carboxamide
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Structure
Formula
C32H38N6O4
Molecular Weight
570.694
Canonical SMILES
CCCC(=O)c1cnn(c1C)-c1ccc(NC(=O)c2cn(CC(=O)N3CCN(CCO)CC3)c3ccc(C)cc23)cc1
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InChI
InChI=1S/C32H38N6O4/c1-4-5-30(40)27-19-33-38(23(27)3)25-9-7-24(8-10-25)34-32(42)28-20-37(29-11-6-22(2)18-26(28)29)21-31(41)36-14-12-35(13-15-36)16-17-39/h6-11,18-20,39H,4-5,12-17,21H2,1-3H3,(H,34,42)
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InChIKey
KKOKADSYNDTGQS-UHFFFAOYSA-N
Physicochemical Property
logP
3.81544
Rotatable Bonds
10
Heavy Atom Count
42
Polar Areas
112.7
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118711097
ChEMBL ID
CHEMBL3325659
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 41 nM
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