General Information of the Compound
Compound ID
CP0389568
Compound Name
(S)-5-(4-((2-cyclopentylethoxy)carbonyl)piperazin-1-yl)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxopentanoic acid
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Structure
Formula
C33H45N5O8S
Molecular Weight
671.817
Canonical SMILES
CN(CCS(C)(=O)=O)c1cc(nc(c1)-c1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCN(CC1)C(=O)OCCC1CCCC1
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InChI
InChI=1S/C33H45N5O8S/c1-36(19-21-47(2,44)45)26-22-28(25-10-4-3-5-11-25)34-29(23-26)31(41)35-27(12-13-30(39)40)32(42)37-15-17-38(18-16-37)33(43)46-20-14-24-8-6-7-9-24/h3-5,10-11,22-24,27H,6-9,12-21H2,1-2H3,(H,35,41)(H,39,40)/t27-/m0/s1
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InChIKey
UBYTXRHCAQSGCE-MHZLTWQESA-N
Physicochemical Property
logP
3.0537
Rotatable Bonds
14
Heavy Atom Count
47
Polar Areas
166.52
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
47

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45269484
ChEMBL ID
CHEMBL556493
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 80 nM
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   LI
   LO
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