General Information of the Compound
Compound ID
CP0439260
Compound Name
(S)-4-(4-(4-(2-(dimethylamino)ethyl)piperazin-1-yl)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
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Structure
Formula
C32H45N7O6
Molecular Weight
623.755
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CCN(CCN(C)C)CC1
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InChI
InChI=1S/C32H45N7O6/c1-4-45-32(44)39-20-18-38(19-21-39)31(43)26(10-11-29(40)41)34-30(42)28-23-25(22-27(33-28)24-8-6-5-7-9-24)37-16-14-36(15-17-37)13-12-35(2)3/h5-9,22-23,26H,4,10-21H2,1-3H3,(H,34,42)(H,40,41)/t26-/m0/s1
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InChIKey
FKGVMOBIDGZEDY-SANMLTNESA-N
Physicochemical Property
logP
1.6961
Rotatable Bonds
12
Heavy Atom Count
45
Polar Areas
138.86
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45270322
ChEMBL ID
CHEMBL538415
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 47 nM
   TI
   LI
   LO
   TS