General Information of the Compound
Compound ID
CP0519069
Compound Name
(4S)4-({[4-(4-Morpholin-4-ylpiperidin-1-yl)6-phenylpyridin-2-yl]carbonyl}amino)5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
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Structure
Formula
C36H50N6O7
Molecular Weight
678.831
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CCC(CC1)N1CCOCC1
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InChI
InChI=1S/C36H50N6O7/c1-2-3-7-22-49-36(47)42-18-16-41(17-19-42)35(46)30(10-11-33(43)44)38-34(45)32-26-29(25-31(37-32)27-8-5-4-6-9-27)39-14-12-28(13-15-39)40-20-23-48-24-21-40/h4-6,8-9,25-26,28,30H,2-3,7,10-24H2,1H3,(H,38,45)(H,43,44)/t30-/m0/s1
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InChIKey
YXVWQYGUIXGKHA-PMERELPUSA-N
Physicochemical Property
logP
3.4838
Rotatable Bonds
13
Heavy Atom Count
49
Polar Areas
144.85
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
49

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45141980
SID: 92391959
ChEMBL ID
CHEMBL603145
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 10 nM
   TI
   LI
   LO
   TS