General Information of the Compound
Compound ID
CP0473493
Compound Name
(4S)5-[4-(Ethoxycarbonyl)iperazin-1-yl]-5-oxo-4-[(pyridin-2-ylcarbonyl)mino]pentanoic Acid
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Structure
Formula
C18H24N4O6
Molecular Weight
392.412
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1ccccn1
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InChI
InChI=1S/C18H24N4O6/c1-2-28-18(27)22-11-9-21(10-12-22)17(26)14(6-7-15(23)24)20-16(25)13-5-3-4-8-19-13/h3-5,8,14H,2,6-7,9-12H2,1H3,(H,20,25)(H,23,24)/t14-/m0/s1
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InChIKey
NXVQZEHIQWRDFL-AWEZNQCLSA-N
Physicochemical Property
logP
0.3455
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
129.14
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46233290
ChEMBL ID
CHEMBL596737
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 5400 nM
   TI
   LI
   LO
   TS