General Information of the Compound
Compound ID
CP0513921
Compound Name
(4S)-4-{[(4-{[Butyl(methyl)amino]carbonyl}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
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Structure
Formula
C33H45N5O7
Molecular Weight
623.751
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)C(=O)N(C)CCCC
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InChI
InChI=1S/C33H45N5O7/c1-4-6-11-21-45-33(44)38-19-17-37(18-20-38)32(43)26(14-15-29(39)40)35-30(41)28-23-25(31(42)36(3)16-7-5-2)22-27(34-28)24-12-9-8-10-13-24/h8-10,12-13,22-23,26H,4-7,11,14-21H2,1-3H3,(H,35,41)(H,39,40)/t26-/m0/s1
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InChIKey
UDCPRUSAEPQIGG-SANMLTNESA-N
Physicochemical Property
logP
4.0549
Rotatable Bonds
15
Heavy Atom Count
45
Polar Areas
149.45
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45139773
SID: 92389692
ChEMBL ID
CHEMBL586227
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 5.8 nM
   TI
   LI
   LO
   TS