General Information of the Compound
Compound ID
CP0421852
Compound Name
(4S)4-[({4-[(1-Isopropylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
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Structure
Formula
C36H51N5O7
Molecular Weight
665.832
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OCC2CCN(CC2)C(C)C)cc(n1)-c1ccccc1
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InChI
InChI=1S/C36H51N5O7/c1-4-5-9-22-47-36(46)41-20-18-40(19-21-41)35(45)30(12-13-33(42)43)38-34(44)32-24-29(23-31(37-32)28-10-7-6-8-11-28)48-25-27-14-16-39(17-15-27)26(2)3/h6-8,10-11,23-24,26-27,30H,4-5,9,12-22,25H2,1-3H3,(H,38,44)(H,42,43)/t30-/m0/s1
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InChIKey
GUBGDGVNPNXEAE-PMERELPUSA-N
Physicochemical Property
logP
4.682
Rotatable Bonds
15
Heavy Atom Count
48
Polar Areas
141.61
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
48

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45142453
SID: 92392444
ChEMBL ID
CHEMBL589282
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 5.5 nM
   TI
   LI
   LO
   TS