General Information of the Compound
Compound ID
CP0509310
Compound Name
(S)-4-(4-(2-(dimethylamino)ethylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid
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Structure
Formula
C28H38N6O6
Molecular Weight
554.648
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(NCCN(C)C)cc(n1)-c1ccccc1
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InChI
InChI=1S/C28H38N6O6/c1-4-40-28(39)34-16-14-33(15-17-34)27(38)22(10-11-25(35)36)31-26(37)24-19-21(29-12-13-32(2)3)18-23(30-24)20-8-6-5-7-9-20/h5-9,18-19,22H,4,10-17H2,1-3H3,(H,29,30)(H,31,37)(H,35,36)/t22-/m0/s1
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InChIKey
JTFDKUJCXKJJCD-QFIPXVFZSA-N
Physicochemical Property
logP
1.986
Rotatable Bonds
12
Heavy Atom Count
40
Polar Areas
144.41
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
8
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45269465
ChEMBL ID
CHEMBL561810
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 270 nM
   TI
   LI
   LO
   TS