General Information of the Compound
Compound ID
CP0532615
Compound Name
(S)-4-(4-((S)-3-(2-(dimethylamino)-2-oxoethoxy)pyrrolidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
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Structure
Formula
C35H48N6O8
Molecular Weight
680.803
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CC[C@@H](C1)OCC(=O)N(C)C
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InChI
InChI=1S/C35H48N6O8/c1-4-5-9-20-48-35(47)40-18-16-39(17-19-40)34(46)28(12-13-32(43)44)37-33(45)30-22-26(21-29(36-30)25-10-7-6-8-11-25)41-15-14-27(23-41)49-24-31(42)38(2)3/h6-8,10-11,21-22,27-28H,4-5,9,12-20,23-24H2,1-3H3,(H,37,45)(H,43,44)/t27-,28-/m0/s1
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InChIKey
JSFHMZINYVWWHB-NSOVKSMOSA-N
Physicochemical Property
logP
2.8663
Rotatable Bonds
15
Heavy Atom Count
49
Polar Areas
161.92
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
49

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46232934
ChEMBL ID
CHEMBL590114
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 5 nM
   TI
   LI
   LO
   TS