General Information of the Compound
Compound ID
CP0452749
Compound Name
(4S)-4-[[5-[2-(diethylamino)-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-(4-ethoxycarbonylpiperazin-1-yl)-5-oxopentanoic acid
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Structure
Formula
C28H38N6O8
Molecular Weight
586.646
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OCC(=O)N(CC)CC)n(n1)-c1ccccc1
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InChI
InChI=1S/C28H38N6O8/c1-4-31(5-2)23(35)19-42-24-18-22(30-34(24)20-10-8-7-9-11-20)26(38)29-21(12-13-25(36)37)27(39)32-14-16-33(17-15-32)28(40)41-6-3/h7-11,18,21H,4-6,12-17,19H2,1-3H3,(H,29,38)(H,36,37)/t21-/m0/s1
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InChIKey
VXUSTAVEUKPFFH-NRFANRHFSA-N
Physicochemical Property
logP
1.3834
Rotatable Bonds
13
Heavy Atom Count
42
Polar Areas
163.61
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44126504
SID: 84978393
ChEMBL ID
CHEMBL2172283
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 5000 nM
   TI
   LI
   LO
   TS