General Information of the Compound
Compound ID
CP0470904
Compound Name
(4S)4-[({4-[(1-Methylpiperidin-4-yl)ethoxy]-6-phenylpyridin-2-yl}carbonyl)mino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid
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Structure
Formula
C34H47N5O7
Molecular Weight
637.778
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OCC2CCN(C)CC2)cc(n1)-c1ccccc1
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InChI
InChI=1S/C34H47N5O7/c1-3-4-8-21-45-34(44)39-19-17-38(18-20-39)33(43)28(11-12-31(40)41)36-32(42)30-23-27(46-24-25-13-15-37(2)16-14-25)22-29(35-30)26-9-6-5-7-10-26/h5-7,9-10,22-23,25,28H,3-4,8,11-21,24H2,1-2H3,(H,36,42)(H,40,41)/t28-/m0/s1
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InChIKey
VBYRVTFQWAWHHU-NDEPHWFRSA-N
Physicochemical Property
logP
3.9034
Rotatable Bonds
14
Heavy Atom Count
46
Polar Areas
141.61
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
46

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45142452
SID: 92392443
ChEMBL ID
CHEMBL592888
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 5.3 nM
   TI
   LI
   LO
   TS