General Information of the Compound
Compound ID
CP0545695
Compound Name
(S)-4-(4-(methyl(2-(methylsulfonyl)ethyl)amino)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
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Structure
Formula
C31H43N5O8S
Molecular Weight
645.779
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N(C)CCS(C)(=O)=O
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InChI
InChI=1S/C31H43N5O8S/c1-4-5-9-19-44-31(41)36-16-14-35(15-17-36)30(40)25(12-13-28(37)38)33-29(39)27-22-24(34(2)18-20-45(3,42)43)21-26(32-27)23-10-7-6-8-11-23/h6-8,10-11,21-22,25H,4-5,9,12-20H2,1-3H3,(H,33,39)(H,37,38)/t25-/m0/s1
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InChIKey
ZQAMEULSVFQGJW-VWLOTQADSA-N
Physicochemical Property
logP
2.6636
Rotatable Bonds
15
Heavy Atom Count
45
Polar Areas
166.52
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45268642
ChEMBL ID
CHEMBL556142
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 15 nM
   TI
   LI
   LO
   TS