General Information of the Compound
Compound ID
CP0508044
Compound Name
(4S)5-[4-(Methoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
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Structure
Formula
C23H26N4O6
Molecular Weight
454.483
Canonical SMILES
COC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cccc(n1)-c1ccccc1
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InChI
InChI=1S/C23H26N4O6/c1-33-23(32)27-14-12-26(13-15-27)22(31)19(10-11-20(28)29)25-21(30)18-9-5-8-17(24-18)16-6-3-2-4-7-16/h2-9,19H,10-15H2,1H3,(H,25,30)(H,28,29)/t19-/m0/s1
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InChIKey
XCUPGEALSJOECC-IBGZPJMESA-N
Physicochemical Property
logP
1.6224
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
129.14
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45271978
ChEMBL ID
CHEMBL549308
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2440 nM
   TI
   LI
   LO
   TS