General Information of the Compound
Compound ID
CP0518792
Compound Name
(4S)5-[4-(N,N-Dimethylglycyl)piperazin-1-yl]-5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
    Show/Hide
Structure
Formula
C29H39N5O5
Molecular Weight
537.661
Canonical SMILES
CN(C)CC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c1cccc(n1)-c1ccccc1
    Show/Hide
InChI
InChI=1S/C29H39N5O5/c1-29(2,3)39-26(36)15-14-24(28(38)34-18-16-33(17-19-34)25(35)20-32(4)5)31-27(37)23-13-9-12-22(30-23)21-10-7-6-8-11-21/h6-13,24H,14-20H2,1-5H3,(H,31,37)/t24-/m0/s1
    Show/Hide
InChIKey
KIWFMQNXXWTXQM-DEOSSOPVSA-N
Physicochemical Property
logP
2.2013
Rotatable Bonds
9
Heavy Atom Count
39
Polar Areas
112.15
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 46233632
ChEMBL ID
CHEMBL597976
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 3590 nM
   TI
   LI
   LO
   TS