General Information of the Compound
Compound ID
CP0502645
Compound Name
(4S)5-(4-Butyrylpiperazin-1-yl)5-oxo-4-{[(6-phenylpyridin-2-yl)carbonyl]amino}pentanoic acid
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Structure
Formula
C29H38N4O5
Molecular Weight
522.646
Canonical SMILES
CCCC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c1cccc(n1)-c1ccccc1
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InChI
InChI=1S/C29H38N4O5/c1-5-10-25(34)32-17-19-33(20-18-32)28(37)24(15-16-26(35)38-29(2,3)4)31-27(36)23-14-9-13-22(30-23)21-11-7-6-8-12-21/h6-9,11-14,24H,5,10,15-20H2,1-4H3,(H,31,36)/t24-/m0/s1
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InChIKey
ULXYRNBVCMCDQO-DEOSSOPVSA-N
Physicochemical Property
logP
3.4398
Rotatable Bonds
9
Heavy Atom Count
38
Polar Areas
108.91
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46233589
ChEMBL ID
CHEMBL597158
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3100 nM
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   LI
   LO
   TS