General Information of the Compound
Compound ID
CP0534171
Compound Name
(4S)-5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[5-[2-[(2S)-2-(methylcarbamoyl)pyrrolidin-1-yl]-2-oxoethoxy]-1-phenylpyrazole-3-carbonyl]amino]-5-oxopentanoic acid
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Structure
Formula
C30H39N7O9
Molecular Weight
641.682
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC)n(n1)-c1ccccc1
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InChI
InChI=1S/C30H39N7O9/c1-3-45-30(44)35-16-14-34(15-17-35)29(43)21(11-12-26(39)40)32-27(41)22-18-25(37(33-22)20-8-5-4-6-9-20)46-19-24(38)36-13-7-10-23(36)28(42)31-2/h4-6,8-9,18,21,23H,3,7,10-17,19H2,1-2H3,(H,31,42)(H,32,41)(H,39,40)/t21-,23-/m0/s1
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InChIKey
UURXPCDHDPCBPQ-GMAHTHKFSA-N
Physicochemical Property
logP
0.252
Rotatable Bonds
12
Heavy Atom Count
46
Polar Areas
192.71
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
10
Complexity
46

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71449929
SID: 163457089
ChEMBL ID
CHEMBL2172265
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 536 nM
   TI
   LI
   LO
   TS