General Information of the Compound
Compound ID
CP0497019
Compound Name
(42S)5-[4-(Ethoxycarbonyl)piperazin-1-yl]-5-oxo-4-{[(4-phenylpyridin-2-yl)carbonyl]amino}pentanoic Acid
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Structure
Formula
C24H28N4O6
Molecular Weight
468.51
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(ccn1)-c1ccccc1
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InChI
InChI=1S/C24H28N4O6/c1-2-34-24(33)28-14-12-27(13-15-28)23(32)19(8-9-21(29)30)26-22(31)20-16-18(10-11-25-20)17-6-4-3-5-7-17/h3-7,10-11,16,19H,2,8-9,12-15H2,1H3,(H,26,31)(H,29,30)/t19-/m0/s1
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InChIKey
SFJHUXJFPJVPIO-IBGZPJMESA-N
Physicochemical Property
logP
2.0125
Rotatable Bonds
8
Heavy Atom Count
34
Polar Areas
129.14
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46233321
ChEMBL ID
CHEMBL599604
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 5700 nM
   TI
   LI
   LO
   TS