General Information of the Compound
Compound ID
CP0522056
Compound Name
(4S)5-[4-(Butoxycarbonyl)piperazin-1-yl]-4-[({4-[4-(methylamino)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxopentanoic Acid
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Structure
Formula
C32H44N6O6
Molecular Weight
608.74
Canonical SMILES
CCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CCC(CC1)NC
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InChI
InChI=1S/C32H44N6O6/c1-3-4-20-44-32(43)38-18-16-37(17-19-38)31(42)26(10-11-29(39)40)35-30(41)28-22-25(36-14-12-24(33-2)13-15-36)21-27(34-28)23-8-6-5-7-9-23/h5-9,21-22,24,26,33H,3-4,10-20H2,1-2H3,(H,35,41)(H,39,40)/t26-/m0/s1
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InChIKey
ONQHMEYJZIJCNS-SANMLTNESA-N
Physicochemical Property
logP
2.9809
Rotatable Bonds
12
Heavy Atom Count
44
Polar Areas
144.41
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
8
Complexity
44

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45141128
SID: 92391081
ChEMBL ID
CHEMBL590418
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2.7 nM
   TI
   LI
   LO
   TS